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Journal Abstract Search

302 related items for PubMed ID: 15456246

  • 1. Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands.
    Malamas MS, Manas ES, McDevitt RE, Gunawan I, Xu ZB, Collini MD, Miller CP, Dinh T, Henderson RA, Keith JC, Harris HA.
    J Med Chem; 2004 Oct 07; 47(21):5021-40. PubMed ID: 15456246
    [Abstract] [Full Text] [Related]

  • 2. Structure-based design of estrogen receptor-beta selective ligands.
    Manas ES, Unwalla RJ, Xu ZB, Malamas MS, Miller CP, Harris HA, Hsiao C, Akopian T, Hum WT, Malakian K, Wolfrom S, Bapat A, Bhat RA, Stahl ML, Somers WS, Alvarez JC.
    J Am Chem Soc; 2004 Nov 24; 126(46):15106-19. PubMed ID: 15548008
    [Abstract] [Full Text] [Related]

  • 3. Synthesis of an estrogen receptor beta-selective radioligand: 5-[18F]fluoro-(2R,3S)-2,3-bis(4-hydroxyphenyl)pentanenitrile and comparison of in vivo distribution with 16alpha-[18F]fluoro-17beta-estradiol.
    Yoo J, Dence CS, Sharp TL, Katzenellenbogen JA, Welch MJ.
    J Med Chem; 2005 Oct 06; 48(20):6366-78. PubMed ID: 16190762
    [Abstract] [Full Text] [Related]

  • 4. Estrogen receptor subtype-selective ligands: asymmetric synthesis and biological evaluation of cis- and trans-5,11-dialkyl- 5,6,11, 12-tetrahydrochrysenes.
    Meyers MJ, Sun J, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA.
    J Med Chem; 1999 Jul 01; 42(13):2456-68. PubMed ID: 10395487
    [Abstract] [Full Text] [Related]

  • 5. Selective estrogen receptor modulators with conformationally restricted side chains. Synthesis and structure-activity relationship of ERalpha-selective tetrahydroisoquinoline ligands.
    Renaud J, Bischoff SF, Buhl T, Floersheim P, Fournier B, Geiser M, Halleux C, Kallen J, Keller H, Ramage P.
    J Med Chem; 2005 Jan 27; 48(2):364-79. PubMed ID: 15658851
    [Abstract] [Full Text] [Related]

  • 6. Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity.
    Compton DR, Sheng S, Carlson KE, Rebacz NA, Lee IY, Katzenellenbogen BS, Katzenellenbogen JA.
    J Med Chem; 2004 Nov 18; 47(24):5872-93. PubMed ID: 15537344
    [Abstract] [Full Text] [Related]

  • 7. Benzopyrans are selective estrogen receptor beta agonists with novel activity in models of benign prostatic hyperplasia.
    Norman BH, Dodge JA, Richardson TI, Borromeo PS, Lugar CW, Jones SA, Chen K, Wang Y, Durst GL, Barr RJ, Montrose-Rafizadeh C, Osborne HE, Amos RM, Guo S, Boodhoo A, Krishnan V.
    J Med Chem; 2006 Oct 19; 49(21):6155-7. PubMed ID: 17034120
    [Abstract] [Full Text] [Related]

  • 8. Estrogen receptor ligands. II. Discovery of benzoxathiins as potent, selective estrogen receptor alpha modulators.
    Kim S, Wu JY, Birzin ET, Frisch K, Chan W, Pai LY, Yang YT, Mosley RT, Fitzgerald PM, Sharma N, Dahllund J, Thorsell AG, DiNinno F, Rohrer SP, Schaeffer JM, Hammond ML.
    J Med Chem; 2004 Apr 22; 47(9):2171-5. PubMed ID: 15084115
    [Abstract] [Full Text] [Related]

  • 9. Evaluation of ligand selectivity using reporter cell lines stably expressing estrogen receptor alpha or beta.
    Escande A, Pillon A, Servant N, Cravedi JP, Larrea F, Muhn P, Nicolas JC, Cavaillès V, Balaguer P.
    Biochem Pharmacol; 2006 May 14; 71(10):1459-69. PubMed ID: 16554039
    [Abstract] [Full Text] [Related]

  • 10. Indazole estrogens: highly selective ligands for the estrogen receptor beta.
    De Angelis M, Stossi F, Carlson KA, Katzenellenbogen BS, Katzenellenbogen JA.
    J Med Chem; 2005 Feb 24; 48(4):1132-44. PubMed ID: 15715479
    [Abstract] [Full Text] [Related]

  • 11. Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1.
    Ye L, Li YL, Mellström K, Mellin C, Bladh LG, Koehler K, Garg N, Garcia Collazo AM, Litten C, Husman B, Persson K, Ljunggren J, Grover G, Sleph PG, George R, Malm J.
    J Med Chem; 2003 Apr 24; 46(9):1580-8. PubMed ID: 12699376
    [Abstract] [Full Text] [Related]

  • 12. Selective estrogen receptor-beta (SERM-beta) compounds modulate raphe nuclei tryptophan hydroxylase-1 (TPH-1) mRNA expression and cause antidepressant-like effects in the forced swim test.
    Clark JA, Alves S, Gundlah C, Rocha B, Birzin ET, Cai SJ, Flick R, Hayes E, Ho K, Warrier S, Pai L, Yudkovitz J, Fleischer R, Colwell L, Li S, Wilkinson H, Schaeffer J, Wilkening R, Mattingly E, Hammond M, Rohrer SP.
    Neuropharmacology; 2012 Nov 24; 63(6):1051-63. PubMed ID: 22796107
    [Abstract] [Full Text] [Related]

  • 13. Identification of the structural requirements of the receptor-binding affinity of diphenolic azoles to estrogen receptors alpha and beta by three-dimensional quantitative structure-activity relationship and structure-activity relationship analysis.
    Demyttenaere-Kovatcheva A, Cronin MT, Benfenati E, Roncaglioni A, Lopiparo E.
    J Med Chem; 2005 Dec 01; 48(24):7628-36. PubMed ID: 16302803
    [Abstract] [Full Text] [Related]

  • 14. Monoaryl-substituted salicylaldoximes as ligands for estrogen receptor beta.
    Minutolo F, Bellini R, Bertini S, Carboni I, Lapucci A, Pistolesi L, Prota G, Rapposelli S, Solati F, Tuccinardi T, Martinelli A, Stossi F, Carlson KE, Katzenellenbogen BS, Katzenellenbogen JA, Macchia M.
    J Med Chem; 2008 Mar 13; 51(5):1344-51. PubMed ID: 18269232
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