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Journal Abstract Search

264 related items for PubMed ID: 15456256

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  • 2. Synthesis of analogs of 2-methoxyestradiol with enhanced inhibitory effects on tubulin polymerization and cancer cell growth.
    Cushman M, He HM, Katzenellenbogen JA, Varma RK, Hamel E, Lin CM, Ram S, Sachdeva YP.
    J Med Chem; 1997 Jul 18; 40(15):2323-34. PubMed ID: 9240348
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  • 3. The effect of exchanging various substituents at the 2-position of 2-methoxyestradiol on cytotoxicity in human cancer cell cultures and inhibition of tubulin polymerization.
    Cushman M, Mohanakrishnan AK, Hollingshead M, Hamel E.
    J Med Chem; 2002 Oct 10; 45(21):4748-54. PubMed ID: 12361402
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  • 4. Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate.
    Jourdan F, Leese MP, Dohle W, Hamel E, Ferrandis E, Newman SP, Purohit A, Reed MJ, Potter BV.
    J Med Chem; 2010 Apr 08; 53(7):2942-51. PubMed ID: 20225862
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  • 9. Antineoplastic agents. 445. Synthesis and evaluation of structural modifications of (Z)- and (E)-combretastatin A-41.
    Pettit GR, Rhodes MR, Herald DL, Hamel E, Schmidt JM, Pettit RK.
    J Med Chem; 2005 Jun 16; 48(12):4087-99. PubMed ID: 15943482
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  • 10. Synthesis and structure-activity relationships of 16-modified analogs of 2-methoxyestradiol.
    Agoston GE, Shah JH, Lavallee TM, Zhan X, Pribluda VS, Treston AM.
    Bioorg Med Chem; 2007 Dec 15; 15(24):7524-37. PubMed ID: 17910916
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  • 11. Antitumor agents. 178. Synthesis and biological evaluation of substituted 2-aryl-1,8-naphthyridin-4(1H)-ones as antitumor agents that inhibit tubulin polymerization.
    Chen K, Kuo SC, Hsieh MC, Mauger A, Lin CM, Hamel E, Lee KH.
    J Med Chem; 1997 Sep 12; 40(19):3049-56. PubMed ID: 9301667
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  • 12. Novel benzylidene-9(10H)-anthracenones as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
    Prinz H, Ishii Y, Hirano T, Stoiber T, Camacho Gomez JA, Schmidt P, Düssmann H, Burger AM, Prehn JH, Günther EG, Unger E, Umezawa K.
    J Med Chem; 2003 Jul 17; 46(15):3382-94. PubMed ID: 12852768
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  • 14. Synthesis, cytotoxic effects and tubulin polymerization inhibition of 1,4-disubstituted 1,2,3-triazole analogs of 2-methoxyestradiol.
    Solum EJ, Vik A, Hansen TV.
    Steroids; 2014 Sep 17; 87():46-53. PubMed ID: 24923521
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  • 15. Antitumor agents. 174. 2',3',4',5,6,7-Substituted 2-phenyl-1,8-naphthyridin-4-ones: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.
    Chen K, Kuo SC, Hsieh MC, Mauger A, Lin CM, Hamel E, Lee KH.
    J Med Chem; 1997 Jul 04; 40(14):2266-75. PubMed ID: 9216846
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  • 16. SAR studies of 2-methoxyestradiol and development of its analogs as probes of anti-tumor mechanisms.
    Ho A, Kim YE, Lee H, Cyrus K, Baek SH, Kim KB.
    Bioorg Med Chem Lett; 2006 Jul 01; 16(13):3383-7. PubMed ID: 16650989
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  • 17. Novel 2-methoxyestradiol analogues with antitumor activity.
    Tinley TL, Leal RM, Randall-Hlubek DA, Cessac JW, Wilkens LR, Rao PN, Mooberry SL.
    Cancer Res; 2003 Apr 01; 63(7):1538-49. PubMed ID: 12670902
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  • 18. Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.
    Wang Z, Yang D, Mohanakrishnan AK, Fanwick PE, Nampoothiri P, Hamel E, Cushman M.
    J Med Chem; 2000 Jun 15; 43(12):2419-29. PubMed ID: 10882369
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  • 19. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP, Wu CY, Hsieh HP, Chang CY, Chen CM, Kuo CC, Chang JY.
    J Med Chem; 2007 Sep 06; 50(18):4548-52. PubMed ID: 17685504
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  • 20. Design, synthesis, and biological evaluation of thiophene analogues of chalcones.
    Romagnoli R, Baraldi PG, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Sarkar T, Hamel E.
    Bioorg Med Chem; 2008 May 15; 16(10):5367-76. PubMed ID: 18440234
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