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Journal Abstract Search

387 related items for PubMed ID: 15456257

  • 1. Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4beta-[(4' '-benzamido)-amino]-4'-o-demethyl-epipodophyllotoxin derivatives.
    Xiao Z, Bastow KF, Vance JR, Sidwell RS, Wang HK, Chen MS, Shi Q, Lee KH.
    J Med Chem; 2004 Oct 07; 47(21):5140-8. PubMed ID: 15456257
    [Abstract] [Full Text] [Related]

  • 2. Antitumor agents. Part 227: Studies on novel 4'-O-demethyl-epipodophyllotoxins as antitumor agents targeting topoisomerase II.
    Xiao Z, Bastow KF, Vance JR, Lee KH.
    Bioorg Med Chem; 2004 Jun 15; 12(12):3339-44. PubMed ID: 15158802
    [Abstract] [Full Text] [Related]

  • 3. Antitumor agents. 194. Synthesis and biological evaluations of 4-beta-mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles.
    Zhu XK, Guan J, Tachibana Y, Bastow KF, Cho SJ, Cheng HH, Cheng YC, Gurwith M, Lee KH.
    J Med Chem; 1999 Jul 01; 42(13):2441-6. PubMed ID: 10395485
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological activity of sulfonamide derivatives of epipodophyllotoxin.
    Guianvarc'h D, Duca M, Boukarim C, Kraus-Berthier L, Léonce S, Pierré A, Pfeiffer B, Renard P, Arimondo PB, Monneret C, Dauzonne D.
    J Med Chem; 2004 Apr 22; 47(9):2365-74. PubMed ID: 15084135
    [Abstract] [Full Text] [Related]

  • 5. Antitumor agents. Part 235: Novel 4'-ester etoposide analogues as potent DNA topoisomerase II inhibitors with improved therapeutic potential.
    Xiao Z, Vance JR, Bastow KF, Brossi A, Wang HK, Lee KH.
    Bioorg Med Chem; 2004 Jun 15; 12(12):3363-9. PubMed ID: 15158805
    [Abstract] [Full Text] [Related]

  • 6. Antitumor agents. 164. Podophenazine, 2'',3''-dichloropodophenazine, benzopodophenazine, and their 4 beta-p-nitroaniline derivatives as novel DNA topoisomerase II inhibitors.
    Cho SJ, Kashiwada Y, Bastow KF, Cheng YC, Lee KH.
    J Med Chem; 1996 Mar 29; 39(7):1396-402. PubMed ID: 8691469
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis, and biological testing of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxin analogues as antitumor agents.
    Reddy PB, Paul DV, Agrawal SK, Saxena AK, Kumar HM, Qazi GN.
    Arch Pharm (Weinheim); 2008 Feb 29; 341(2):126-31. PubMed ID: 18214838
    [Abstract] [Full Text] [Related]

  • 8. Novel carbamate derivatives of 4-beta-amino-4'-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation.
    Duca M, Arimondo PB, Léonce S, Pierré A, Pfeiffer B, Monneret C, Dauzonne D.
    Org Biomol Chem; 2005 Mar 21; 3(6):1074-80. PubMed ID: 15750651
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4'-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents.
    Kamal A, Suresh P, Ramaiah MJ, Mallareddy A, Imthiajali S, Pushpavalli SN, Lavanya A, Pal-Bhadra M.
    Bioorg Med Chem; 2012 Mar 15; 20(6):2054-66. PubMed ID: 22364746
    [Abstract] [Full Text] [Related]

  • 10. Synthesis and biological evaluation of new 4beta-anilino- and 4beta-imido-substituted podophyllotoxin congeners.
    Kamal A, Gayatri NL, Reddy DR, Mohan Reddy PS, Arifuddin M, Dastidar SG, Kondapi AK, Rajkumar M.
    Bioorg Med Chem; 2005 Nov 15; 13(22):6218-25. PubMed ID: 16061385
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and biological study of a new series of 4'-demethylepipodophyllotoxin derivatives.
    Duca M, Guianvarc'h D, Meresse P, Bertounesque E, Dauzonne D, Kraus-Berthier L, Thirot S, Léonce S, Pierré A, Pfeiffer B, Renard P, Arimondo PB, Monneret C.
    J Med Chem; 2005 Jan 27; 48(2):593-603. PubMed ID: 15658872
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and cytotoxic activity of novel derivatives of 4'-demethylepipodophyllotoxin.
    Chen SW, Tian X, Tu YQ.
    Bioorg Med Chem Lett; 2004 Oct 18; 14(20):5063-6. PubMed ID: 15380199
    [Abstract] [Full Text] [Related]

  • 13. Podophyllotoxin analogs: effects on DNA topoisomerase II, tubulin polymerization, human tumor KB cells, and their VP-16-resistant variants.
    Liu SY, Hwang BD, Haruna M, Imakura Y, Lee KH, Cheng YC.
    Mol Pharmacol; 1989 Jul 18; 36(1):78-82. PubMed ID: 2546053
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis, biological evaluation and QSAR studies of novel bisepipodophyllotoxins as cytotoxic agents.
    Kamal A, Laxman E, Khanna GB, Reddy PS, Rehana T, Arifuddin M, Neelima K, Kondapi AK, Dastidar SG.
    Bioorg Med Chem; 2004 Aug 01; 12(15):4197-209. PubMed ID: 15246096
    [Abstract] [Full Text] [Related]

  • 15. Synthesis of 4β-carbamoyl epipodophyllotoxins as potential antitumour agents.
    Kamal A, Kumar BA, Suresh P, Juvekar A, Zingde S.
    Bioorg Med Chem; 2011 May 01; 19(9):2975-9. PubMed ID: 21489802
    [Abstract] [Full Text] [Related]

  • 16. Novel 4 beta-anilino-podophyllotoxin derivatives: design synthesis and biological evaluation as potent DNA-topoisomerase II poisons and anti-MDR agents.
    Hu C, Xu D, Du W, Qian S, Wang L, Lou J, He Q, Yang B, Hu Y.
    Mol Biosyst; 2010 Feb 01; 6(2):410-20. PubMed ID: 20094661
    [Abstract] [Full Text] [Related]

  • 17. Antitumor agents. 3. Design, synthesis, and biological evaluation of new pyridoisoquinolindione and dihydrothienoquinolindione derivatives with potent cytotoxic activity.
    Bolognese A, Correale G, Manfra M, Lavecchia A, Mazzoni O, Novellino E, La Colla P, Sanna G, Loddo R.
    J Med Chem; 2004 Feb 12; 47(4):849-58. PubMed ID: 14761187
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and antitumor activity of new glycosides of epipodophyllotoxin, analogues of etoposide, and NK 611.
    Daley L, Guminski Y, Demerseman P, Kruczynski A, Etiévant C, Imbert T, Hill BT, Monneret C.
    J Med Chem; 1998 Nov 05; 41(23):4475-85. PubMed ID: 9804687
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and biological evaluation of 4beta-[(4-substituted)-1,2,3-triazol-1-yl]podophyllotoxins as potential anticancer agents.
    Reddy PB, Agrawal SK, Singh S, Bhat BA, Saxena AK, Kumar HM, Qazi GN.
    Chem Biodivers; 2008 Sep 05; 5(9):1792-802. PubMed ID: 18816530
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of 4β-acrylamidopodophyllotoxin congeners as DNA damaging agents.
    Kamal A, Suresh P, Janaki Ramaiah M, Mallareddy A, Kumar BA, Raju P, Vinay Gopal J, Pushpavalli SN, Lavanya A, Sarma P, Pal-Bhadra M.
    Bioorg Med Chem; 2011 Aug 01; 19(15):4589-600. PubMed ID: 21737288
    [Abstract] [Full Text] [Related]

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