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Journal Abstract Search

324 related items for PubMed ID: 15456274

  • 1. Design and synthesis of novel indole beta-diketo acid derivatives as HIV-1 integrase inhibitors.
    Sechi M, Derudas M, Dallocchio R, Dessì A, Bacchi A, Sannia L, Carta F, Palomba M, Ragab O, Chan C, Shoemaker R, Sei S, Dayam R, Neamati N.
    J Med Chem; 2004 Oct 07; 47(21):5298-310. PubMed ID: 15456274
    [Abstract] [Full Text] [Related]

  • 2. Design and synthesis of novel β-diketo derivatives as HIV-1 integrase inhibitors.
    Hu L, Zhang S, He X, Luo Z, Wang X, Liu W, Qin X.
    Bioorg Med Chem; 2012 Jan 01; 20(1):177-82. PubMed ID: 22154762
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  • 3. Conformationally restrained carbazolone-containing alpha,gamma-diketo acids as inhibitors of HIV integrase.
    Li X, Vince R.
    Bioorg Med Chem; 2006 May 01; 14(9):2942-55. PubMed ID: 16386908
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  • 4. New 4-[(1-benzyl-1H-indol-3-yl)carbonyl]-3-hydroxyfuran-2(5H)-ones, beta-diketo acid analogs as HIV-1 integrase inhibitors.
    Ferro S, Barreca ML, De Luca L, Rao A, Monforte AM, Debyser Z, Witvrouw M, Chimirri A.
    Arch Pharm (Weinheim); 2007 Jun 01; 340(6):292-8. PubMed ID: 17562561
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  • 5. Synthesis and biological evaluation of purine derivatives incorporating metal chelating ligands as HIV integrase inhibitors.
    Li X, Vince R.
    Bioorg Med Chem; 2006 Aug 15; 14(16):5742-55. PubMed ID: 16753300
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, biological evaluation and molecular modeling studies of quinolonyl diketo acid derivatives: new structural insight into the HIV-1 integrase inhibition.
    Vandurm P, Guiguen A, Cauvin C, Georges B, Le Van K, Michaux C, Cardona C, Mbemba G, Mouscadet JF, Hevesi L, Van Lint C, Wouters J.
    Eur J Med Chem; 2011 May 15; 46(5):1749-56. PubMed ID: 21385662
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  • 7. Rational design and synthesis of novel dimeric diketoacid-containing inhibitors of HIV-1 integrase: implication for binding to two metal ions on the active site of integrase.
    Long YQ, Jiang XH, Dayam R, Sanchez T, Shoemaker R, Sei S, Neamati N.
    J Med Chem; 2004 May 06; 47(10):2561-73. PubMed ID: 15115398
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  • 8. Design, synthesis, and biological evaluation of novel hybrid dicaffeoyltartaric/diketo acid and tetrazole-substituted L-chicoric acid analogue inhibitors of human immunodeficiency virus type 1 integrase.
    Crosby DC, Lei X, Gibbs CG, McDougall BR, Robinson WE, Reinecke MG.
    J Med Chem; 2010 Nov 25; 53(22):8161-75. PubMed ID: 20977258
    [Abstract] [Full Text] [Related]

  • 9. Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
    Dayam R, Sanchez T, Neamati N.
    J Med Chem; 2005 Dec 15; 48(25):8009-15. PubMed ID: 16335925
    [Abstract] [Full Text] [Related]

  • 10. Pharmacophore-based design of HIV-1 integrase strand-transfer inhibitors.
    Barreca ML, Ferro S, Rao A, De Luca L, Zappalà M, Monforte AM, Debyser Z, Witvrouw M, Chimirri A.
    J Med Chem; 2005 Nov 03; 48(22):7084-8. PubMed ID: 16250669
    [Abstract] [Full Text] [Related]

  • 11. From ligand to complexes. Part 2. Remarks on human immunodeficiency virus type 1 integrase inhibition by beta-diketo acid metal complexes.
    Bacchi A, Biemmi M, Carcelli M, Carta F, Compari C, Fisicaro E, Rogolino D, Sechi M, Sippel M, Sotriffer CA, Sanchez TW, Neamati N.
    J Med Chem; 2008 Nov 27; 51(22):7253-64. PubMed ID: 18983138
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  • 13. Triketoacid inhibitors of HIV-integrase: a new chemotype useful for probing the integrase pharmacophore.
    Walker MA, Johnson T, Ma Z, Banville J, Remillard R, Kim O, Zhang Y, Staab A, Wong H, Torri A, Samanta H, Lin Z, Deminie C, Terry B, Krystal M, Meanwell N.
    Bioorg Med Chem Lett; 2006 Jun 01; 16(11):2920-4. PubMed ID: 16546383
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  • 17. Design, synthesis, and anti-integrase activity of catechol-DKA hybrids.
    Maurin C, Bailly F, Mbemba G, Mouscadet JF, Cotelle P.
    Bioorg Med Chem; 2006 May 01; 14(9):2978-84. PubMed ID: 16412645
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