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196 related items for PubMed ID: 15471868

  • 1. Dimerization of the human receptors for prostacyclin and thromboxane facilitates thromboxane receptor-mediated cAMP generation.
    Wilson SJ, Roche AM, Kostetskaia E, Smyth EM.
    J Biol Chem; 2004 Dec 17; 279(51):53036-47. PubMed ID: 15471868
    [Abstract] [Full Text] [Related]

  • 2. The alpha, but not the beta, isoform of the human thromboxane A2 receptor is a target for prostacyclin-mediated desensitization.
    Walsh MT, Foley JF, Kinsella BT.
    J Biol Chem; 2000 Jul 07; 275(27):20412-23. PubMed ID: 10827090
    [Abstract] [Full Text] [Related]

  • 3. Regulation of thromboxane receptor trafficking through the prostacyclin receptor in vascular smooth muscle cells: role of receptor heterodimerization.
    Wilson SJ, Dowling JK, Zhao L, Carnish E, Smyth EM.
    Arterioscler Thromb Vasc Biol; 2007 Feb 07; 27(2):290-6. PubMed ID: 17110599
    [Abstract] [Full Text] [Related]

  • 4. Dominant negative actions of human prostacyclin receptor variant through dimerization: implications for cardiovascular disease.
    Ibrahim S, Tetruashvily M, Frey AJ, Wilson SJ, Stitham J, Hwa J, Smyth EM.
    Arterioscler Thromb Vasc Biol; 2010 Sep 07; 30(9):1802-9. PubMed ID: 20522800
    [Abstract] [Full Text] [Related]

  • 5. Regulation of the human prostanoid TPalpha and TPbeta receptor isoforms mediated through activation of the EP(1) and IP receptors.
    Walsh MT, Kinsella BT.
    Br J Pharmacol; 2000 Oct 07; 131(3):601-9. PubMed ID: 11015313
    [Abstract] [Full Text] [Related]

  • 6. Investigation of the role of the carboxyl-terminal tails of the alpha and beta isoforms of the human thromboxane A(2) receptor (TP) in mediating receptor:effector coupling.
    Walsh M, Foley JF, Kinsella BT.
    Biochim Biophys Acta; 2000 Apr 17; 1496(2-3):164-82. PubMed ID: 10771086
    [Abstract] [Full Text] [Related]

  • 7. Heterodimerization of the alpha and beta isoforms of the human thromboxane receptor enhances isoprostane signaling.
    Wilson SJ, McGinley K, Huang AJ, Smyth EM.
    Biochem Biophys Res Commun; 2007 Jan 12; 352(2):397-403. PubMed ID: 17134677
    [Abstract] [Full Text] [Related]

  • 8. Physiological significance of thromboxane A(2) receptor dimerization.
    Sasaki M, Miyosawa K, Ohkubo S, Nakahata N.
    J Pharmacol Sci; 2006 Apr 12; 100(4):263-70. PubMed ID: 16565578
    [Abstract] [Full Text] [Related]

  • 9. Phosphorylation of the thromboxane receptor alpha, the predominant isoform expressed in human platelets.
    Habib A, FitzGerald GA, Maclouf J.
    J Biol Chem; 1999 Jan 29; 274(5):2645-51. PubMed ID: 9915793
    [Abstract] [Full Text] [Related]

  • 10. Reversal of angiogenesis in vitro, induction of apoptosis, and inhibition of AKT phosphorylation in endothelial cells by thromboxane A(2).
    Gao Y, Yokota R, Tang S, Ashton AW, Ware JA.
    Circ Res; 2000 Oct 27; 87(9):739-45. PubMed ID: 11055976
    [Abstract] [Full Text] [Related]

  • 11. Biased suppression of TP homodimerization and signaling through disruption of a TM GxxxGxxxL helical interaction motif.
    Frey AJ, Ibrahim S, Gleim S, Hwa J, Smyth EM.
    J Lipid Res; 2013 Jun 27; 54(6):1678-1690. PubMed ID: 23493750
    [Abstract] [Full Text] [Related]

  • 12. Protein kinase A-mediated phosphorylation of serine 357 of the mouse prostacyclin receptor regulates its coupling to G(s)-, to G(i)-, and to G(q)-coupled effector signaling.
    Lawler OA, Miggin SM, Kinsella BT.
    J Biol Chem; 2001 Sep 07; 276(36):33596-607. PubMed ID: 11443126
    [Abstract] [Full Text] [Related]

  • 13. Thromboxane A(2) receptor mediated activation of the mitogen activated protein kinase cascades in human uterine smooth muscle cells.
    Miggin SM, Kinsella BT.
    Biochim Biophys Acta; 2001 May 28; 1539(1-2):147-62. PubMed ID: 11389977
    [Abstract] [Full Text] [Related]

  • 14. Evidence for human thromboxane receptor heterogeneity using a novel series of 9,11-cyclic carbonate derivatives of prostaglandin F2 alpha.
    Krauss AH, Woodward DF, Gibson LL, Protzman CE, Williams LS, Burk RM, Gac TS, Roof MB, Abbas F, Marshall K, Senior J.
    Br J Pharmacol; 1996 Mar 28; 117(6):1171-80. PubMed ID: 8882612
    [Abstract] [Full Text] [Related]

  • 15. TRA-418, a novel compound having both thromboxane A(2) receptor antagonistic and prostaglandin I(2) receptor agonistic activities: its antiplatelet effects in human and animal platelets.
    Yamada N, Miyamoto M, Isogaya M, Suzuki M, Ikezawa S, Ohno M, Otake A, Umemura K.
    J Thromb Haemost; 2003 Aug 28; 1(8):1813-9. PubMed ID: 12911598
    [Abstract] [Full Text] [Related]

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  • 17. Heterodimerization with the prostacyclin receptor triggers thromboxane receptor relocation to lipid rafts.
    Ibrahim S, McCartney A, Markosyan N, Smyth EM.
    Arterioscler Thromb Vasc Biol; 2013 Jan 28; 33(1):60-6. PubMed ID: 23162015
    [Abstract] [Full Text] [Related]

  • 18. Milrinone attenuates thromboxane receptor-mediated hyperresponsiveness in hypoxic pulmonary arterial myocytes.
    Santhosh KT, Elkhateeb O, Nolette N, Outbih O, Halayko AJ, Dakshinamurti S.
    Br J Pharmacol; 2011 Jul 28; 163(6):1223-36. PubMed ID: 21385177
    [Abstract] [Full Text] [Related]

  • 19. Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn.
    Majed BH, Khalil RA.
    Pharmacol Rev; 2012 Jul 28; 64(3):540-82. PubMed ID: 22679221
    [Abstract] [Full Text] [Related]

  • 20. Internalization and sequestration of the human prostacyclin receptor.
    Smyth EM, Austin SC, Reilly MP, FitzGerald GA.
    J Biol Chem; 2000 Oct 13; 275(41):32037-45. PubMed ID: 10889200
    [Abstract] [Full Text] [Related]

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