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Journal Abstract Search


390 related items for PubMed ID: 15482922

  • 1. Macrocyclic ketone analogues of halichondrin B.
    Zheng W, Seletsky BM, Palme MH, Lydon PJ, Singer LA, Chase CE, Lemelin CA, Shen Y, Davis H, Tremblay L, Towle MJ, Salvato KA, Wels BF, Aalfs KK, Kishi Y, Littlefield BA, Yu MJ.
    Bioorg Med Chem Lett; 2004 Nov 15; 14(22):5551-4. PubMed ID: 15482922
    [Abstract] [Full Text] [Related]

  • 2. In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B.
    Towle MJ, Salvato KA, Budrow J, Wels BF, Kuznetsov G, Aalfs KK, Welsh S, Zheng W, Seletsky BM, Palme MH, Habgood GJ, Singer LA, Dipietro LV, Wang Y, Chen JJ, Quincy DA, Davis A, Yoshimatsu K, Kishi Y, Yu MJ, Littlefield BA.
    Cancer Res; 2001 Feb 01; 61(3):1013-21. PubMed ID: 11221827
    [Abstract] [Full Text] [Related]

  • 3. Structurally simplified macrolactone analogues of halichondrin B.
    Seletsky BM, Wang Y, Hawkins LD, Palme MH, Habgood GJ, DiPietro LV, Towle MJ, Salvato KA, Wels BF, Aalfs KK, Kishi Y, Littlefield BA, Yu MJ.
    Bioorg Med Chem Lett; 2004 Nov 15; 14(22):5547-50. PubMed ID: 15482921
    [Abstract] [Full Text] [Related]

  • 4. Comparison of the activities of the truncated halichondrin B analog NSC 707389 (E7389) with those of the parent compound and a proposed binding site on tubulin.
    Dabydeen DA, Burnett JC, Bai R, Verdier-Pinard P, Hickford SJ, Pettit GR, Blunt JW, Munro MH, Gussio R, Hamel E.
    Mol Pharmacol; 2006 Dec 15; 70(6):1866-75. PubMed ID: 16940412
    [Abstract] [Full Text] [Related]

  • 5. The halichondrins and E7389.
    Jackson KL, Henderson JA, Phillips AJ.
    Chem Rev; 2009 Jul 15; 109(7):3044-79. PubMed ID: 19534494
    [No Abstract] [Full Text] [Related]

  • 6. Structure-activity relationships of halichondrin B analogues: modifications at C.30-C.38.
    Wang Y, Habgood GJ, Christ WJ, Kishi Y, Littlefield BA, Yu MJ.
    Bioorg Med Chem Lett; 2000 May 15; 10(10):1029-32. PubMed ID: 10843209
    [Abstract] [Full Text] [Related]

  • 7. Complex synthesis yields breast-cancer therapy.
    Ledford H.
    Nature; 2010 Dec 02; 468(7324):608-9. PubMed ID: 21124423
    [No Abstract] [Full Text] [Related]

  • 8. Natural product drug discovery: the successful optimization of ISP-1 and halichondrin B.
    Yeung BK.
    Curr Opin Chem Biol; 2011 Aug 02; 15(4):523-8. PubMed ID: 21684798
    [Abstract] [Full Text] [Related]

  • 9. Induction of morphological and biochemical apoptosis following prolonged mitotic blockage by halichondrin B macrocyclic ketone analog E7389.
    Kuznetsov G, Towle MJ, Cheng H, Kawamura T, TenDyke K, Liu D, Kishi Y, Yu MJ, Littlefield BA.
    Cancer Res; 2004 Aug 15; 64(16):5760-6. PubMed ID: 15313917
    [Abstract] [Full Text] [Related]

  • 10. Second generation synthesis of C27-C35 building block of E7389, a synthetic halichondrin analogue.
    Yang YR, Kim DS, Kishi Y.
    Org Lett; 2009 Oct 15; 11(20):4516-9. PubMed ID: 19754145
    [Abstract] [Full Text] [Related]

  • 11. Atom-based enumeration: new eribulin analogues with low susceptibility to P-glycoprotein-mediated drug efflux.
    Yu MJ, Zheng W, Tendyke K.
    Bioorg Med Chem Lett; 2012 Dec 15; 22(24):7363-6. PubMed ID: 23141916
    [Abstract] [Full Text] [Related]

  • 12. Eribulin, a simplified ketone analog of the tubulin inhibitor halichondrin B, for the potential treatment of cancer.
    Newman S.
    Curr Opin Investig Drugs; 2007 Dec 15; 8(12):1057-66. PubMed ID: 18058576
    [Abstract] [Full Text] [Related]

  • 13. Practical stereoselective synthesis of eribulin fragment toward building a hybrid macrocyclic toolbox.
    Jimmidi R, Guduru SK, Arya P.
    Org Lett; 2015 Feb 06; 17(3):468-71. PubMed ID: 25583003
    [Abstract] [Full Text] [Related]

  • 14. Total synthesis of cavicularin and riccardin C: addressing the synthesis of an arene that adopts a boat configuration.
    Harrowven DC, Woodcock T, Howes PD.
    Angew Chem Int Ed Engl; 2005 Jun 20; 44(25):3899-901. PubMed ID: 15900530
    [No Abstract] [Full Text] [Related]

  • 15. Radanamycin, a macrocyclic chimera of radicicol and geldanamycin.
    Wang M, Shen G, Blagg BS.
    Bioorg Med Chem Lett; 2006 May 01; 16(9):2459-62. PubMed ID: 16464590
    [Abstract] [Full Text] [Related]

  • 16. A unified strategy for the total syntheses of eribulin and a macrolactam analogue of halichondrin B.
    Nicolaou KC, Pan S, Shelke Y, Rigol S, Bao R, Das D, Ye Q.
    Proc Natl Acad Sci U S A; 2022 Aug 09; 119(32):e2208938119. PubMed ID: 35930662
    [Abstract] [Full Text] [Related]

  • 17. Immunomodulatory Effects of Halichondrin Isolated from Marine Sponges and Its Synthetic Analogs in Oncological Applications.
    Dissanayake DS, Nagahawatta DP, Lee JS, Jeon YJ.
    Mar Drugs; 2024 Sep 20; 22(9):. PubMed ID: 39330307
    [Abstract] [Full Text] [Related]

  • 18. Synthesis and biological evaluation of spongistatin/altohyrtin analogues: E-ring dehydration and C46 side-chain truncation.
    Paterson I, Aceña JL, Bach J, Chen DY, Coster MJ.
    Chem Commun (Camb); 2003 Feb 21; (4):462-3. PubMed ID: 12638950
    [Abstract] [Full Text] [Related]

  • 19. Novel C2-C3' N-peptide linked macrocyclic taxoids. Part 2: synthesis and biological activities of docetaxel analogues with a peptide side chain at C2 and their macrocyclic derivatives.
    Larroque AL, Dubois J, Thoret S, Aubert G, Chiaroni A, Guéritte F, Guénard D.
    Bioorg Med Chem; 2007 Jan 01; 15(1):563-74. PubMed ID: 17064914
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and antitumour activity of new muricatacin and goniofufurone analogues.
    Popsavin V, Srećo B, Krstić I, Popsavin M, Kojić V, Bogdanović G.
    Eur J Med Chem; 2006 Oct 01; 41(10):1217-22. PubMed ID: 16891043
    [Abstract] [Full Text] [Related]


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