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Journal Abstract Search

168 related items for PubMed ID: 15486075

  • 1. Interactions between CYP2C9 and CYP2C19 in reconstituted binary systems influence their catalytic activity: possible rationale for the inability of CYP2C19 to catalyze methoxychlor demethylation in human liver microsomes.
    Hazai E, Kupfer D.
    Drug Metab Dispos; 2005 Jan; 33(1):157-64. PubMed ID: 15486075
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  • 4. Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation.
    Stresser DM, Kupfer D.
    Drug Metab Dispos; 1998 Sep; 26(9):868-74. PubMed ID: 9733665
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  • 5. Prosubstrates of CYP3A4, the major human hepatic cytochrome P450: transformation into substrates by other P450 isoforms.
    Stresser DM, Kupfer D.
    Biochem Pharmacol; 1998 Jun 01; 55(11):1861-71. PubMed ID: 9714305
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  • 6. CYP2C19 participates in tolbutamide hydroxylation by human liver microsomes.
    Wester MR, Lasker JM, Johnson EF, Raucy JL.
    Drug Metab Dispos; 2000 Mar 01; 28(3):354-9. PubMed ID: 10681382
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  • 7. Cytochrome P450 2C9 catalyzes indomethacin O-demethylation in human liver microsomes.
    Nakajima M, Inoue T, Shimada N, Tokudome S, Yamamoto T, Kuroiwa Y.
    Drug Metab Dispos; 1998 Mar 01; 26(3):261-6. PubMed ID: 9492390
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  • 9. Cynomolgus monkey cytochrome P450 2C43: cDNA cloning, heterologous expression, purification and characterization.
    Mitsuda M, Iwasaki M, Asahi S.
    J Biochem; 2006 May 01; 139(5):865-72. PubMed ID: 16751594
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  • 10. Interaction of delavirdine with human liver microsomal cytochrome P450: inhibition of CYP2C9, CYP2C19, and CYP2D6.
    Voorman RL, Payne NA, Wienkers LC, Hauer MJ, Sanders PE.
    Drug Metab Dispos; 2001 Jan 01; 29(1):41-7. PubMed ID: 11124228
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  • 11. Evaluation of 3-O-methylfluorescein as a selective fluorometric substrate for CYP2C19 in human liver microsomes.
    Sudsakorn S, Skell J, Williams DA, O'Shea TJ, Liu H.
    Drug Metab Dispos; 2007 Jun 01; 35(6):841-7. PubMed ID: 17332142
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  • 12. The inhibitory effect of polyunsaturated fatty acids on human CYP enzymes.
    Yao HT, Chang YW, Lan SJ, Chen CT, Hsu JT, Yeh TK.
    Life Sci; 2006 Nov 25; 79(26):2432-40. PubMed ID: 16978661
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  • 13. Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes.
    Miyazawa M, Shindo M, Shimada T.
    Drug Metab Dispos; 2002 May 25; 30(5):602-7. PubMed ID: 11950794
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  • 14. Chlorpropamide 2-hydroxylation is catalysed by CYP2C9 and CYP2C19 in vitro: chlorpropamide disposition is influenced by CYP2C9, but not by CYP2C19 genetic polymorphism.
    Shon JH, Yoon YR, Kim MJ, Kim KA, Lim YC, Liu KH, Shin DH, Lee CH, Cha IJ, Shin JG.
    Br J Clin Pharmacol; 2005 May 25; 59(5):552-63. PubMed ID: 15842554
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  • 15. Effects of CYP2C19 genotype and CYP2C9 on fluoxetine N-demethylation in human liver microsomes.
    Liu ZQ, Shu Y, Huang SL, Wang LS, He N, Zhou HH.
    Acta Pharmacol Sin; 2001 Jan 25; 22(1):85-90. PubMed ID: 11730569
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  • 16. Human CYP2C19 is a major omeprazole 5-hydroxylase, as demonstrated with recombinant cytochrome P450 enzymes.
    Karam WG, Goldstein JA, Lasker JM, Ghanayem BI.
    Drug Metab Dispos; 1996 Oct 25; 24(10):1081-7. PubMed ID: 8894508
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  • 17. Metabolism of the proestrogenic pesticide methoxychlor by hepatic P450 monooxygenases in rats and humans. Dual pathways involving novel ortho ring-hydroxylation by CYP2B.
    Dehal SS, Kupfer D.
    Drug Metab Dispos; 1994 Oct 25; 22(6):937-46. PubMed ID: 7895613
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  • 18. Metabolism of the endocrine disruptor pesticide-methoxychlor by human P450s: pathways involving a novel catechol metabolite.
    Hu Y, Kupfer D.
    Drug Metab Dispos; 2002 Sep 25; 30(9):1035-42. PubMed ID: 12167570
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  • 19. Amino acid residues affecting the activities of human cytochrome P450 2C9 and 2C19.
    Niwa T, Kageyama A, Kishimoto K, Yabusaki Y, Ishibashi F, Katagiri M.
    Drug Metab Dispos; 2002 Aug 25; 30(8):931-6. PubMed ID: 12124312
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  • 20. Conversion of the HIV protease inhibitor nelfinavir to a bioactive metabolite by human liver CYP2C19.
    Hirani VN, Raucy JL, Lasker JM.
    Drug Metab Dispos; 2004 Dec 25; 32(12):1462-7. PubMed ID: 15448116
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