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139 related items for PubMed ID: 15486947

  • 1. In vivo mutational analysis of liver DNA in gpt delta transgenic rats treated with the hepatocarcinogens N-nitrosopyrrolidine, 2-amino-3-methylimidazo[4,5-f]quinoline, and di(2-ethylhexyl)phthalate.
    Kanki K, Nishikawa A, Masumura K, Umemura T, Imazawa T, Kitamura Y, Nohmi T, Hirose M.
    Mol Carcinog; 2005 Jan; 42(1):9-17. PubMed ID: 15486947
    [Abstract] [Full Text] [Related]

  • 2. Quantitative analysis of mutagenicity and carcinogenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in F344 gpt delta transgenic rats.
    Gi M, Fujioka M, Totsuka Y, Matsumoto M, Masumura K, Kakehashi A, Yamaguchi T, Fukushima S, Wanibuchi H.
    Mutagenesis; 2019 Sep 20; 34(3):279-287. PubMed ID: 31233596
    [Abstract] [Full Text] [Related]

  • 3. Mutational analysis of the liver, colon and kidney of Big Blue rats treated with 2-amino-3-methylimidazo[4,5-f]quinoline.
    Bol SA, Horlbeck J, Markovic J, de Boer JG, Turesky RJ, Constable A.
    Carcinogenesis; 2000 Jan 20; 21(1):1-6. PubMed ID: 10607726
    [Abstract] [Full Text] [Related]

  • 4. A cyclic N7,C-8 guanine adduct of N-nitrosopyrrolidine (NPYR): formation in nucleic acids and excretion in the urine of NPYR-treated rats.
    Wang M, Hecht SS.
    Chem Res Toxicol; 1997 Jul 20; 10(7):772-8. PubMed ID: 9250411
    [Abstract] [Full Text] [Related]

  • 5. Validation study of the combined repeated-dose toxicity and genotoxicity assay using gpt delta rats.
    Akagi J, Toyoda T, Cho YM, Mizuta Y, Nohmi T, Nishikawa A, Ogawa K.
    Cancer Sci; 2015 May 20; 106(5):529-41. PubMed ID: 25683344
    [Abstract] [Full Text] [Related]

  • 6. Qualitative and quantitative approaches in the dose-response assessment of genotoxic carcinogens.
    Fukushima S, Gi M, Kakehashi A, Wanibuchi H, Matsumoto M.
    Mutagenesis; 2016 May 20; 31(3):341-6. PubMed ID: 26152227
    [Abstract] [Full Text] [Related]

  • 7. Mutagenicity of 2-amino-3-methylimidazo[4,5-f]quinoline in human lymphoblastoid cells.
    Leong-Morgenthaler PM, Op Het Velt C, Jaccaud E, Turesky RJ.
    Carcinogenesis; 1998 Oct 20; 19(10):1749-54. PubMed ID: 9806154
    [Abstract] [Full Text] [Related]

  • 8. Dammar resin, a non-mutagen, induces [corrected] oxidative stress and metabolic enzymes in the liver of gpt delta transgenic mouse which is different from a mutagen, 2-amino-3-methylimidazo[4,5-f]quinoline.
    Xie XL, Wei M, Kakehashi A, Yamano S, Okabe K, Tajiri M, Wanibuchi H.
    Mutat Res; 2012 Oct 09; 748(1-2):29-35. PubMed ID: 22766412
    [Abstract] [Full Text] [Related]

  • 9. 1,3-butadiene: cancer, mutations, and adducts. Part II: Roles of two metabolites of 1,3-butadiene in mediating its in vivo genotoxicity.
    Recio L, Saranko CJ, Steen AM.
    Res Rep Health Eff Inst; 2000 Mar 09; (92):49-87; discussion 141-9. PubMed ID: 10925839
    [Abstract] [Full Text] [Related]

  • 10. Formation and differential removal of C-8 and N2-guanine adducts of the food carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline in the liver, kidney, and colorectum of the rat.
    Turesky RJ, Markovic J, Aeschlimann JM.
    Chem Res Toxicol; 1996 Mar 09; 9(2):397-402. PubMed ID: 8839041
    [Abstract] [Full Text] [Related]

  • 11. Suppression of hepatocyte apoptosis and induction of DNA synthesis by the rat and mouse hepatocarcinogen diethylhexylphlathate (DEHP) and the mouse hepatocarcinogen 1,4-dichlorobenzene (DCB).
    James NH, Soames AR, Roberts RA.
    Arch Toxicol; 1998 Dec 09; 72(12):784-90. PubMed ID: 9950075
    [Abstract] [Full Text] [Related]

  • 12. Lack of genotoxic mechanisms in early-stage furan-induced hepatocellular tumorigenesis in gpt delta rats.
    Hibi D, Yokoo Y, Suzuki Y, Ishii Y, Jin M, Kijima A, Nohmi T, Nishikawa A, Umemura T.
    J Appl Toxicol; 2017 Feb 09; 37(2):142-149. PubMed ID: 27143483
    [Abstract] [Full Text] [Related]

  • 13. Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse.
    Masumura K, Totsuka Y, Wakabayashi K, Nohmi T.
    Carcinogenesis; 2003 Dec 09; 24(12):1985-93. PubMed ID: 12970073
    [Abstract] [Full Text] [Related]

  • 14. The C8-2'-deoxyguanosine adduct of 2-amino-3-methylimidazo[1,2-d]naphthalene, a carbocyclic analogue of the potent mutagen 2-amino-3-methylimidazo[4,5-f]quinoline, is a block to replication in vitro.
    Christov PP, Chowdhury G, Garmendia CA, Wang F, Stover JS, Elmquist CE, Kozekova A, Angel KC, Turesky RJ, Stone MP, Guengerich FP, Rizzo CJ.
    Chem Res Toxicol; 2010 Jun 21; 23(6):1076-88. PubMed ID: 20377178
    [Abstract] [Full Text] [Related]

  • 15. Mutagenic specificity of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the supF shuttle vector system.
    Endo H, Schut HA, Snyderwine EG.
    Cancer Res; 1994 Jul 15; 54(14):3745-51. PubMed ID: 8033094
    [Abstract] [Full Text] [Related]

  • 16. No-observed effect levels for carcinogenicity and for in vivo mutagenicity of a genotoxic carcinogen.
    Hoshi M, Morimura K, Wanibuchi H, Wei M, Okochi E, Ushijima T, Takaoka K, Fukushima S.
    Toxicol Sci; 2004 Oct 15; 81(2):273-9. PubMed ID: 15282409
    [Abstract] [Full Text] [Related]

  • 17. The potential role of chemically induced hyperplasia in the carcinogenic activity of the hypolipidemic carcinogens.
    Butterworth BE, Loury DJ, Smith-Oliver T, Cattley RC.
    Toxicol Ind Health; 1987 Jun 15; 3(2):129-49. PubMed ID: 3303446
    [Abstract] [Full Text] [Related]

  • 18. Development of a Medium-term Animal Model Using gpt Delta Rats to Evaluate Chemical Carcinogenicity and Genotoxicity.
    Matsushita K, Kijima A, Ishii Y, Takasu S, Jin M, Kuroda K, Kawaguchi H, Miyoshi N, Nohmi T, Ogawa K, Umemura T.
    J Toxicol Pathol; 2013 Mar 15; 26(1):19-27. PubMed ID: 23723564
    [Abstract] [Full Text] [Related]

  • 19. DNA adduct formation by 2-amino-3-methylimidazo [4,5-f] quinoline (IQ) in rat colon.
    Lin CX, Monden Y, Umemoto A.
    J Med Invest; 2001 Feb 15; 48(1-2):102-8. PubMed ID: 11286010
    [Abstract] [Full Text] [Related]

  • 20. DNA adduct formation of the food-derived mutagen 2-amino-3-methylimidazo[4,5-f]quinoline in nonhuman primates undergoing carcinogen bioassay.
    Turesky RJ, Gremaud E, Markovic J, Snyderwine EG.
    Chem Res Toxicol; 1996 Mar 15; 9(2):403-8. PubMed ID: 8839042
    [Abstract] [Full Text] [Related]

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