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Journal Abstract Search

293 related items for PubMed ID: 15492232

  • 1.
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  • 2. Orphan nuclear receptor constitutive active/androstane receptor-mediated alterations in DNA methylation during phenobarbital promotion of liver tumorigenesis.
    Phillips JM, Yamamoto Y, Negishi M, Maronpot RR, Goodman JI.
    Toxicol Sci; 2007 Mar; 96(1):72-82. PubMed ID: 17172636
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  • 4. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression.
    Roth A, Looser R, Kaufmann M, Blättler SM, Rencurel F, Huang W, Moore DD, Meyer UA.
    Mol Pharmacol; 2008 Apr; 73(4):1282-9. PubMed ID: 18187584
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  • 6. Impaired nuclear translocation of CAR in hepatic preneoplastic lesions: association with an attenuated CYP2B induction by phenobarbital.
    Numazawa S, Shindo S, Maruyama K, Chibana F, Kawahara Y, Ashino T, Tanaka S, Yoshida T.
    FEBS Lett; 2005 Jul 04; 579(17):3560-4. PubMed ID: 15953603
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  • 7. Evaluation of mutant frequencies of chemically induced tumors and normal tissues in lambda/cII transgenic mice.
    Mirsalis JC, Shimon JA, Johnson A, Fairchild D, Kanazawa N, Nguyen T, de Boer J, Glickman B, Winegar RA.
    Environ Mol Mutagen; 2005 Jul 04; 45(1):17-35. PubMed ID: 15605353
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  • 8. Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital.
    Loeppen S, Schneider D, Gaunitz F, Gebhardt R, Kurek R, Buchmann A, Schwarz M.
    Cancer Res; 2002 Oct 15; 62(20):5685-8. PubMed ID: 12384525
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  • 9. Different pathways of constitutive androstane receptor-mediated liver hypertrophy and hepatocarcinogenesis in mice treated with piperonyl butoxide or decabromodiphenyl ether.
    Sakamoto Y, Inoue K, Takahashi M, Taketa Y, Kodama Y, Nemoto K, Degawa M, Gamou T, Ozawa S, Nishikawa A, Yoshida M.
    Toxicol Pathol; 2013 Oct 15; 41(8):1078-92. PubMed ID: 23531792
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  • 10. The increased CAR-dependent metabolism of thyroid hormones in mice with high cancer susceptibility.
    Pakharukova M, Smetanina M, Kaledin V, Obut T, Merkulova T.
    Life Sci; 2010 Sep 25; 87(13-14):439-44. PubMed ID: 20816995
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  • 11. Constitutive active/androstane receptor promotes hepatocarcinogenesis in a mouse model of non-alcoholic steatohepatitis.
    Takizawa D, Kakizaki S, Horiguchi N, Yamazaki Y, Tojima H, Mori M.
    Carcinogenesis; 2011 Apr 25; 32(4):576-83. PubMed ID: 21173431
    [Abstract] [Full Text] [Related]

  • 12. Multiple genes exhibit phenobarbital-induced constitutive active/androstane receptor-mediated DNA methylation changes during liver tumorigenesis and in liver tumors.
    Phillips JM, Goodman JI.
    Toxicol Sci; 2009 Apr 25; 108(2):273-89. PubMed ID: 19233941
    [Abstract] [Full Text] [Related]

  • 13. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
    Wagner M, Halilbasic E, Marschall HU, Zollner G, Fickert P, Langner C, Zatloukal K, Denk H, Trauner M.
    Hepatology; 2005 Aug 25; 42(2):420-30. PubMed ID: 15986414
    [Abstract] [Full Text] [Related]

  • 14. Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXR.
    Braeuning A, Gavrilov A, Brown S, Wolf CR, Henderson CJ, Schwarz M.
    Toxicol Sci; 2014 Aug 01; 140(2):259-70. PubMed ID: 24863967
    [Abstract] [Full Text] [Related]

  • 15. Di-(2-ethylhexyl)-phthalate (DEHP) activates the constitutive androstane receptor (CAR): a novel signalling pathway sensitive to phthalates.
    Eveillard A, Mselli-Lakhal L, Mogha A, Lasserre F, Polizzi A, Pascussi JM, Guillou H, Martin PG, Pineau T.
    Biochem Pharmacol; 2009 Jun 01; 77(11):1735-46. PubMed ID: 19428328
    [Abstract] [Full Text] [Related]

  • 16. Mechanism of the paradoxical, inhibitory effect of phenobarbital on hepatocarcinogenesis initiated in infant B6C3F1 mice with diethylnitrosamine.
    Lee GH, Ooasa T, Osanai M.
    Cancer Res; 1998 Apr 15; 58(8):1665-9. PubMed ID: 9563480
    [Abstract] [Full Text] [Related]

  • 17. Cytoplasmic accumulation of the nuclear receptor CAR by a tetratricopeptide repeat protein in HepG2 cells.
    Kobayashi K, Sueyoshi T, Inoue K, Moore R, Negishi M.
    Mol Pharmacol; 2003 Nov 15; 64(5):1069-75. PubMed ID: 14573755
    [Abstract] [Full Text] [Related]

  • 18. Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1.
    Braeuning A, Sanna R, Huelsken J, Schwarz M.
    Drug Metab Dispos; 2009 May 15; 37(5):1138-45. PubMed ID: 19237511
    [Abstract] [Full Text] [Related]

  • 19. Dose-response modeling of early molecular and cellular key events in the CAR-mediated hepatocarcinogenesis pathway.
    Geter DR, Bhat VS, Gollapudi BB, Sura R, Hester SD.
    Toxicol Sci; 2014 Apr 15; 138(2):425-45. PubMed ID: 24449422
    [Abstract] [Full Text] [Related]

  • 20. Gender dictates the nuclear receptor-mediated regulation of CYP3A44.
    Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW.
    Drug Metab Dispos; 2007 Jan 15; 35(1):36-42. PubMed ID: 17020958
    [Abstract] [Full Text] [Related]

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