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Journal Abstract Search

151 related items for PubMed ID: 15498796

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  • 2. Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids.
    Martel-Pelletier J, Mineau F, Fahmi H, Laufer S, Reboul P, Boileau C, Lavigne M, Pelletier JP.
    Arthritis Rheum; 2004 Dec; 50(12):3925-33. PubMed ID: 15593193
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  • 3. Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition.
    Paredes Y, Massicotte F, Pelletier JP, Martel-Pelletier J, Laufer S, Lajeunesse D.
    Arthritis Rheum; 2002 Jul; 46(7):1804-12. PubMed ID: 12124864
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  • 6. Licofelone (ML-3000), a dual inhibitor of 5-lipoxygenase and cyclooxygenase, reduces the level of cartilage chondrocyte death in vivo in experimental dog osteoarthritis: inhibition of pro-apoptotic factors.
    Boileau C, Martel-Pelletier J, Jouzeau JY, Netter P, Moldovan F, Laufer S, Tries S, Pelletier JP.
    J Rheumatol; 2002 Jul; 29(7):1446-53. PubMed ID: 12136904
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  • 7. Hsp90{beta} and p130(cas): novel regulatory factors of MMP-13 expression in human osteoarthritic chondrocytes.
    Fan Z, Tardif G, Hum D, Duval N, Pelletier JP, Martel-Pelletier J.
    Ann Rheum Dis; 2009 Jun; 68(6):976-82. PubMed ID: 18593760
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  • 8. Collagenase 3 production by human osteoarthritic chondrocytes in response to growth factors and cytokines is a function of the physiologic state of the cells.
    Tardif G, Pelletier JP, Dupuis M, Geng C, Cloutier JM, Martel-Pelletier J.
    Arthritis Rheum; 1999 Jun; 42(6):1147-58. PubMed ID: 10366107
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  • 9. Licofelone, a novel 5-LOX/COX-inhibitor, attenuates leukocyte rolling and adhesion on endothelium under flow.
    Ulbrich H, Soehnlein O, Xie X, Eriksson EE, Lindbom L, Albrecht W, Laufer S, Dannhardt G.
    Biochem Pharmacol; 2005 Jul 01; 70(1):30-6. PubMed ID: 15894291
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  • 10. Interleukin-1 beta induction of matrix metalloproteinase-1 transcription in chondrocytes requires ERK-dependent activation of CCAAT enhancer-binding protein-beta.
    Raymond L, Eck S, Mollmark J, Hays E, Tomek I, Kantor S, Elliott S, Vincenti M.
    J Cell Physiol; 2006 Jun 01; 207(3):683-8. PubMed ID: 16453302
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  • 13. Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade.
    Tavolari S, Bonafè M, Marini M, Ferreri C, Bartolini G, Brighenti E, Manara S, Tomasi V, Laufer S, Guarnieri T.
    Carcinogenesis; 2008 Feb 01; 29(2):371-80. PubMed ID: 18033773
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  • 14. CCAAT/enhancer binding protein beta mediates expression of matrix metalloproteinase 13 in human articular chondrocytes in inflammatory arthritis.
    Hayashida M, Okazaki K, Fukushi J, Sakamoto A, Iwamoto Y.
    Arthritis Rheum; 2009 Mar 01; 60(3):708-16. PubMed ID: 19248099
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  • 15. Anticancer effects of licofelone (ML-3000) in prostate cancer cells.
    Narayanan NK, Nargi D, Attur M, Abramson SB, Narayanan BA.
    Anticancer Res; 2007 Mar 01; 27(4B):2393-402. PubMed ID: 17695530
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  • 16. Differential patterns of response to doxycycline and transforming growth factor beta1 in the down-regulation of collagenases in osteoarthritic and normal human chondrocytes.
    Shlopov BV, Smith GN, Cole AA, Hasty KA.
    Arthritis Rheum; 1999 Apr 01; 42(4):719-27. PubMed ID: 10211886
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  • 17. Interleukin-1beta induces MMP-9 expression via p42/p44 MAPK, p38 MAPK, JNK, and nuclear factor-kappaB signaling pathways in human tracheal smooth muscle cells.
    Liang KC, Lee CW, Lin WN, Lin CC, Wu CB, Luo SF, Yang CM.
    J Cell Physiol; 2007 Jun 01; 211(3):759-70. PubMed ID: 17311279
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  • 18. The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases.
    Pelletier JP, Boileau C, Boily M, Brunet J, Mineau F, Geng C, Reboul P, Laufer S, Lajeunesse D, Martel-Pelletier J.
    Arthritis Res Ther; 2005 Jun 01; 7(5):R1091-102. PubMed ID: 16207326
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  • 19. Role of Wnt-5A in interleukin-1beta-induced matrix metalloproteinase expression in rabbit temporomandibular joint condylar chondrocytes.
    Ge X, Ma X, Meng J, Zhang C, Ma K, Zhou C.
    Arthritis Rheum; 2009 Sep 01; 60(9):2714-22. PubMed ID: 19714632
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  • 20. PGE2 inhibits chondrocyte differentiation through PKA and PKC signaling.
    Li TF, Zuscik MJ, Ionescu AM, Zhang X, Rosier RN, Schwarz EM, Drissi H, O'Keefe RJ.
    Exp Cell Res; 2004 Oct 15; 300(1):159-69. PubMed ID: 15383323
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