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Journal Abstract Search


235 related items for PubMed ID: 15504758

  • 1. Electrophysiological characterization of the SK channel blockers methyl-laudanosine and methyl-noscapine in cell lines and rat brain slices.
    Scuvée-Moreau J, Boland A, Graulich A, Van Overmeire L, D'hoedt D, Graulich-Lorge F, Thomas E, Abras A, Stocker M, Liégeois JF, Seutin V.
    Br J Pharmacol; 2004 Nov; 143(6):753-64. PubMed ID: 15504758
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  • 3. Synthesis and radioligand binding studies of C-5- and C-8-substituted 1-(3,4-dimethoxybenzyl)-2,2-dimethyl-1,2,3,4-tetrahydroisoquinoliniums as SK channel blockers related to N-methyl-laudanosine and N-methyl-noscapine.
    Graulich A, Scuvée-Moreau J, Seutin V, Liégeois JF.
    J Med Chem; 2005 Jul 28; 48(15):4972-82. PubMed ID: 16033276
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  • 4. Synthesis and biological evaluation of N-methyl-laudanosine iodide analogues as potential SK channel blockers.
    Graulich A, Mercier F, Scuvée-Moreau J, Seutin V, Liégeois JF.
    Bioorg Med Chem; 2005 Feb 15; 13(4):1201-9. PubMed ID: 15670929
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  • 7. SK3 is an important component of K(+) channels mediating the afterhyperpolarization in cultured rat SCG neurones.
    Hosseini R, Benton DC, Dunn PM, Jenkinson DH, Moss GW.
    J Physiol; 2001 Sep 01; 535(Pt 2):323-34. PubMed ID: 11533126
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  • 10. Modulation of small conductance calcium-activated potassium (SK) channels: a new challenge in medicinal chemistry.
    Liégeois JF, Mercier F, Graulich A, Graulich-Lorge F, Scuvée-Moreau J, Seutin V.
    Curr Med Chem; 2003 Apr 01; 10(8):625-47. PubMed ID: 12678783
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  • 11. Small conductance Ca2+-activated K+ channels as targets of CNS drug development.
    Blank T, Nijholt I, Kye MJ, Spiess J.
    Curr Drug Targets CNS Neurol Disord; 2004 Jun 01; 3(3):161-7. PubMed ID: 15180477
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  • 14. Bis-tetrahydroisoquinoline derivatives: AG525E1, a new step in the search for non-quaternary non-peptidic small conductance Ca(2+)-activated K(+) channel blockers.
    Graulich A, Lamy C, Alleva L, Dilly S, Chavatte P, Wouters J, Seutin V, Liégeois JF.
    Bioorg Med Chem Lett; 2008 Jun 01; 18(11):3440-5. PubMed ID: 18436444
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  • 17. Inhibitory gating modulation of small conductance Ca2+-activated K+ channels by the synthetic compound (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (NS8593) reduces afterhyperpolarizing current in hippocampal CA1 neurons.
    Strøbaek D, Hougaard C, Johansen TH, Sørensen US, Nielsen EØ, Nielsen KS, Taylor RD, Pedarzani P, Christophersen P.
    Mol Pharmacol; 2006 Nov 01; 70(5):1771-82. PubMed ID: 16926279
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