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134 related items for PubMed ID: 15517874
1. Rapamycin inhibits Akt-mediated oncogenic transformation and tumor growth. Liu X, Powlas J, Shi Y, Oleksijew AX, Shoemaker AR, De Jong R, Oltersdorf T, Giranda VL, Luo Y. Anticancer Res; 2004; 24(5A):2697-704. PubMed ID: 15517874 [Abstract] [Full Text] [Related]
2. Involvement of the Akt/mTOR pathway on EGF-induced cell transformation. Nomura M, He Z, Koyama I, Ma WY, Miyamoto K, Dong Z. Mol Carcinog; 2003 Sep; 38(1):25-32. PubMed ID: 12949840 [Abstract] [Full Text] [Related]
3. Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. Yang L, Dan HC, Sun M, Liu Q, Sun XM, Feldman RI, Hamilton AD, Polokoff M, Nicosia SV, Herlyn M, Sebti SM, Cheng JQ. Cancer Res; 2004 Jul 01; 64(13):4394-9. PubMed ID: 15231645 [Abstract] [Full Text] [Related]
4. Transforming activity of the RL-akt gene, a c-akt gene activated by long terminal repeat insertion in murine leukemia RL(male symbol)1 cells. Tanino M, Matsuo M, Uenaka A, Tsukuda K, Ouchida M, Nakayama E, Shimizu K. Mol Carcinog; 1999 Dec 01; 26(4):286-97. PubMed ID: 10569805 [Abstract] [Full Text] [Related]
5. Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck. Amornphimoltham P, Patel V, Sodhi A, Nikitakis NG, Sauk JJ, Sausville EA, Molinolo AA, Gutkind JS. Cancer Res; 2005 Nov 01; 65(21):9953-61. PubMed ID: 16267020 [Abstract] [Full Text] [Related]
6. A small molecule compound inhibits AKT pathway in ovarian cancer cell lines. Tang HJ, Jin X, Wang S, Yang D, Cao Y, Chen J, Gossett DR, Lin J. Gynecol Oncol; 2006 Feb 01; 100(2):308-17. PubMed ID: 16209885 [Abstract] [Full Text] [Related]
7. Preferential dependence of breast cancer cells versus normal cells on integrin-linked kinase for protein kinase B/Akt activation and cell survival. Troussard AA, McDonald PC, Wederell ED, Mawji NM, Filipenko NR, Gelmon KA, Kucab JE, Dunn SE, Emerman JT, Bally MB, Dedhar S. Cancer Res; 2006 Jan 01; 66(1):393-403. PubMed ID: 16397254 [Abstract] [Full Text] [Related]
8. Akt1 induces extracellular matrix invasion and matrix metalloproteinase-2 activity in mouse mammary epithelial cells. Park BK, Zeng X, Glazer RI. Cancer Res; 2001 Oct 15; 61(20):7647-53. PubMed ID: 11606407 [Abstract] [Full Text] [Related]
9. From Rapa Nui to rapamycin: targeting PI3K/Akt/mTOR for cancer therapy. Georgakis GV, Younes A. Expert Rev Anticancer Ther; 2006 Jan 15; 6(1):131-40. PubMed ID: 16375650 [Abstract] [Full Text] [Related]
10. c-Src-p38 mitogen-activated protein kinase signaling is required for Akt activation in response to ionizing radiation. Kim MJ, Byun JY, Yun CH, Park IC, Lee KH, Lee SJ. Mol Cancer Res; 2008 Dec 15; 6(12):1872-80. PubMed ID: 19074832 [Abstract] [Full Text] [Related]
14. A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin. Ma PC, Schaefer E, Christensen JG, Salgia R. Clin Cancer Res; 2005 Mar 15; 11(6):2312-9. PubMed ID: 15788682 [Abstract] [Full Text] [Related]