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Journal Abstract Search

244 related items for PubMed ID: 15519569

  • 21. Synthesis and structure-activity relationships of indole and benzimidazole piperazines as histamine H(4) receptor antagonists.
    Terzioglu N, van Rijn RM, Bakker RA, De Esch IJ, Leurs R.
    Bioorg Med Chem Lett; 2004 Nov 01; 14(21):5251-6. PubMed ID: 15454206
    [Abstract] [Full Text] [Related]

  • 22. Major advances in the development of histamine H4 receptor ligands.
    Smits RA, Leurs R, de Esch IJ.
    Drug Discov Today; 2009 Aug 01; 14(15-16):745-53. PubMed ID: 19477292
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  • 23. Synthesis and pharmacological identification of neutral histamine H1-receptor antagonists.
    Govoni M, Bakker RA, van de Wetering I, Smit MJ, Menge WM, Timmerman H, Elz S, Schunack W, Leurs R.
    J Med Chem; 2003 Dec 18; 46(26):5812-24. PubMed ID: 14667234
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  • 24. G protein-dependent pharmacology of histamine H3 receptor ligands: evidence for heterogeneous active state receptor conformations.
    Krueger KM, Witte DG, Ireland-Denny L, Miller TR, Baranowski JL, Buckner S, Milicic I, Esbenshade TA, Hancock AA.
    J Pharmacol Exp Ther; 2005 Jul 18; 314(1):271-81. PubMed ID: 15821027
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  • 25. INCB38579, a novel and potent histamine H₄ receptor small molecule antagonist with anti-inflammatory pain and anti-pruritic functions.
    Shin N, Covington M, Bian D, Zhuo J, Bowman K, Li Y, Soloviev M, Qian DQ, Feldman P, Leffet L, He X, He Wang K, Krug K, Bell D, Czerniak P, Hu Z, Zhao H, Zhang J, Yeleswaram S, Yao W, Newton R, Scherle P.
    Eur J Pharmacol; 2012 Jan 30; 675(1-3):47-56. PubMed ID: 22155710
    [Abstract] [Full Text] [Related]

  • 26. Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.
    Watanabe M, Kazuta Y, Hayashi H, Yamada S, Matsuda A, Shuto S.
    J Med Chem; 2006 Sep 07; 49(18):5587-96. PubMed ID: 16942032
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  • 27. The histamine H₄ receptor: targeting inflammatory disorders.
    Walter M, Kottke T, Stark H.
    Eur J Pharmacol; 2011 Oct 01; 668(1-2):1-5. PubMed ID: 21741967
    [Abstract] [Full Text] [Related]

  • 28. Phenoxybenzamine and benextramine, but not 4-diphenylacetoxy-N-[2-chloroethyl]piperidine hydrochloride, display irreversible noncompetitive antagonism at G protein-coupled receptors.
    Bodenstein J, Venter DP, Brink CB.
    J Pharmacol Exp Ther; 2005 Aug 01; 314(2):891-905. PubMed ID: 15857948
    [Abstract] [Full Text] [Related]

  • 29. A rapid, homogeneous, fluorescence polarization binding assay for peroxisome proliferator-activated receptors alpha and gamma using a fluorescein-tagged dual PPARalpha/gamma activator.
    Seethala R, Golla R, Ma Z, Zhang H, O'Malley K, Lippy J, Cheng L, Mookhtiar K, Farrelly D, Zhang L, Hariharan N, Cheng PT.
    Anal Biochem; 2007 Apr 15; 363(2):263-74. PubMed ID: 17335769
    [Abstract] [Full Text] [Related]

  • 30. Toward efficient drug screening by homogeneous assays based on the development of new fluorescent vasopressin and oxytocin receptor ligands.
    Albizu L, Teppaz G, Seyer R, Bazin H, Ansanay H, Manning M, Mouillac B, Durroux T.
    J Med Chem; 2007 Oct 04; 50(20):4976-85. PubMed ID: 17850055
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  • 31. Histamine H4 receptor antagonists: the new antihistamines?
    Fung-Leung WP, Thurmond RL, Ling P, Karlsson L.
    Curr Opin Investig Drugs; 2004 Nov 04; 5(11):1174-83. PubMed ID: 15573868
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  • 32. Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives.
    Gbahou F, Vincent L, Humbert-Claude M, Tardivel-Lacombe J, Chabret C, Arrang JM.
    Br J Pharmacol; 2006 Apr 04; 147(7):744-54. PubMed ID: 16432504
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  • 33. A scintillation proximity assay for human interleukin-5 (hIL-5) high-affinity binding in insect cells coexpressing hIL-5 receptor alpha and beta subunits.
    Zhang J, Wu P, Kuvelkar R, Schwartz JL, Egan RW, Billah MM, Wang P.
    Anal Biochem; 1999 Mar 01; 268(1):134-42. PubMed ID: 10036172
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  • 34. Identification of small molecule antagonists of the human mas-related gene-X1 receptor.
    Kunapuli P, Lee S, Zheng W, Alberts M, Kornienko O, Mull R, Kreamer A, Hwang JI, Simon MI, Strulovici B.
    Anal Biochem; 2006 Apr 01; 351(1):50-61. PubMed ID: 16510108
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  • 35. Identification of 2-arylbenzimidazoles as potent human histamine H4 receptor ligands.
    Lee-Dutra A, Arienti KL, Buzard DJ, Hack MD, Khatuya H, Desai PJ, Nguyen S, Thurmond RL, Karlsson L, Edwards JP, Breitenbucher JG.
    Bioorg Med Chem Lett; 2006 Dec 01; 16(23):6043-8. PubMed ID: 16990005
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  • 36. Preparation and biological evaluation of indole, benzimidazole, and thienopyrrole piperazine carboxamides: potent human histamine h(4) antagonists.
    Venable JD, Cai H, Chai W, Dvorak CA, Grice CA, Jablonowski JA, Shah CR, Kwok AK, Ly KS, Pio B, Wei J, Desai PJ, Jiang W, Nguyen S, Ling P, Wilson SJ, Dunford PJ, Thurmond RL, Lovenberg TW, Karlsson L, Carruthers NI, Edwards JP.
    J Med Chem; 2005 Dec 29; 48(26):8289-98. PubMed ID: 16366610
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  • 37. Histamine H4 receptor agonists.
    Igel P, Dove S, Buschauer A.
    Bioorg Med Chem Lett; 2010 Dec 15; 20(24):7191-9. PubMed ID: 21044842
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  • 38. Development of a homogeneous high-throughput live-cell G-protein-coupled receptor binding assay.
    Lee PH, Miller SC, van Staden C, Cromwell EF.
    J Biomol Screen; 2008 Sep 15; 13(8):748-54. PubMed ID: 18460694
    [Abstract] [Full Text] [Related]

  • 39. Delineation of agonist binding to the human histamine H4 receptor using mutational analysis, homology modeling, and ab initio calculations.
    Jongejan A, Lim HD, Smits RA, de Esch IJ, Haaksma E, Leurs R.
    J Chem Inf Model; 2008 Jul 15; 48(7):1455-63. PubMed ID: 18553960
    [Abstract] [Full Text] [Related]

  • 40. A simple and powerful flow cytometric method for the simultaneous determination of multiple parameters at G protein-coupled receptor subtypes.
    Schneider E, Mayer M, Ziemek R, Li L, Hutzler C, Bernhardt G, Buschauer A.
    Chembiochem; 2006 Sep 15; 7(9):1400-9. PubMed ID: 16888730
    [Abstract] [Full Text] [Related]

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