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Journal Abstract Search

585 related items for PubMed ID: 15519905

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  • 2. A pharmacokinetic-pharmacodynamic model for the quantitative prediction of dofetilide clinical QT prolongation from human ether-a-go-go-related gene current inhibition data.
    Jonker DM, Kenna LA, Leishman D, Wallis R, Milligan PA, Jonsson EN.
    Clin Pharmacol Ther; 2005 Jun; 77(6):572-82. PubMed ID: 15961988
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  • 6. Acidification alters antiarrhythmic drug blockade of the ether-a-go-go-related Gene (HERG) Channels.
    Dong DL, Li Z, Wang HZ, Du ZM, Song WH, Yang BF.
    Basic Clin Pharmacol Toxicol; 2004 May; 94(5):209-12. PubMed ID: 15125690
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  • 7. Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel.
    Davie C, Pierre-Valentin J, Pollard C, Standen N, Mitcheson J, Alexander P, Thong B.
    J Cardiovasc Electrophysiol; 2004 Nov; 15(11):1302-9. PubMed ID: 15574182
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  • 10. Investigating dynamic protocol-dependence of hERG potassium channel inhibition at 37 degrees C: Cisapride versus dofetilide.
    Milnes JT, Witchel HJ, Leaney JL, Leishman DJ, Hancox JC.
    J Pharmacol Toxicol Methods; 2010 Nov; 61(2):178-91. PubMed ID: 20172036
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  • 11. A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.
    Rampe D, Roy ML, Dennis A, Brown AM.
    FEBS Lett; 1997 Nov 03; 417(1):28-32. PubMed ID: 9395068
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  • 12. Molecular determinants of inactivation and dofetilide block in ether a-go-go (EAG) channels and EAG-related K(+) channels.
    Ficker E, Jarolimek W, Brown AM.
    Mol Pharmacol; 2001 Dec 03; 60(6):1343-8. PubMed ID: 11723241
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  • 13. Block of HERG-carried K+ currents by the new repolarization delaying agent H 345/52.
    Amos GJ, Jacobson I, Duker G, Carlsson L.
    J Cardiovasc Electrophysiol; 2003 Jun 03; 14(6):651-8. PubMed ID: 12875428
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  • 14. Fluorescently labeled analogues of dofetilide as high-affinity fluorescence polarization ligands for the human ether-a-go-go-related gene (hERG) channel.
    Singleton DH, Boyd H, Steidl-Nichols JV, Deacon M, Groot MJ, Price D, Nettleton DO, Wallace NK, Troutman MD, Williams C, Boyd JG.
    J Med Chem; 2007 Jun 28; 50(13):2931-41. PubMed ID: 17536794
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  • 15. Pharmacological inhibition of the hERG potassium channel is modulated by extracellular but not intracellular acidosis.
    DU CY, El Harchi A, Zhang YH, Orchard CH, Hancox JC.
    J Cardiovasc Electrophysiol; 2011 Oct 28; 22(10):1163-70. PubMed ID: 21489024
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  • 16. Comparison of the effects of metoclopramide and domperidone on HERG channels.
    Claassen S, Zünkler BJ.
    Pharmacology; 2005 Apr 28; 74(1):31-6. PubMed ID: 15640612
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  • 17. Allosteric modulators of the hERG K(+) channel: radioligand binding assays reveal allosteric characteristics of dofetilide analogs.
    Yu Z, Klaasse E, Heitman LH, Ijzerman AP.
    Toxicol Appl Pharmacol; 2014 Jan 01; 274(1):78-86. PubMed ID: 24200993
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  • 19. Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide.
    Kiehn J, Lacerda AE, Wible B, Brown AM.
    Circulation; 1996 Nov 15; 94(10):2572-9. PubMed ID: 8921803
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  • 20. Evaluation of the rubidium efflux assay for preclinical identification of HERG blockade.
    Chaudhary KW, O'Neal JM, Mo ZL, Fermini B, Gallavan RH, Bahinski A.
    Assay Drug Dev Technol; 2006 Feb 15; 4(1):73-82. PubMed ID: 16506891
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