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Journal Abstract Search

240 related items for PubMed ID: 15522263

  • 1. Organ slices for the evaluation of human drug toxicity.
    Vickers AE, Fisher RL.
    Chem Biol Interact; 2004 Nov 01; 150(1):87-96. PubMed ID: 15522263
    [Abstract] [Full Text] [Related]

  • 2. Tissue slices for the evaluation of metabolism-based toxicity with the example of diclofenac.
    Vickers AE.
    Chem Biol Interact; 2009 Apr 15; 179(1):9-16. PubMed ID: 19000659
    [Abstract] [Full Text] [Related]

  • 3. Precision-cut organ slices to investigate target organ injury.
    Vickers AE, Fisher RL.
    Expert Opin Drug Metab Toxicol; 2005 Dec 15; 1(4):687-99. PubMed ID: 16863433
    [Abstract] [Full Text] [Related]

  • 4. Factors to consider in the use of stem cells for pharmaceutic drug development and for chemical safety assessment.
    Trosko JE, Chang CC.
    Toxicology; 2010 Mar 30; 270(1):18-34. PubMed ID: 19948204
    [Abstract] [Full Text] [Related]

  • 5. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.
    EFSA GMO Panel Working Group on Animal Feeding Trials.
    Food Chem Toxicol; 2008 Mar 30; 46 Suppl 1():S2-70. PubMed ID: 18328408
    [Abstract] [Full Text] [Related]

  • 6. Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.
    Ganter B, Tugendreich S, Pearson CI, Ayanoglu E, Baumhueter S, Bostian KA, Brady L, Browne LJ, Calvin JT, Day GJ, Breckenridge N, Dunlea S, Eynon BP, Furness LM, Ferng J, Fielden MR, Fujimoto SY, Gong L, Hu C, Idury R, Judo MS, Kolaja KL, Lee MD, McSorley C, Minor JM, Nair RV, Natsoulis G, Nguyen P, Nicholson SM, Pham H, Roter AH, Sun D, Tan S, Thode S, Tolley AM, Vladimirova A, Yang J, Zhou Z, Jarnagin K.
    J Biotechnol; 2005 Sep 29; 119(3):219-44. PubMed ID: 16005536
    [Abstract] [Full Text] [Related]

  • 7. Evaluation of drug-induced injury and human response in precision-cut tissue slices.
    Vickers AE, Fisher RL.
    Xenobiotica; 2013 Jan 29; 43(1):29-40. PubMed ID: 23094640
    [Abstract] [Full Text] [Related]

  • 8. [Development of antituberculous drugs: current status and future prospects].
    Tomioka H, Namba K.
    Kekkaku; 2006 Dec 29; 81(12):753-74. PubMed ID: 17240921
    [Abstract] [Full Text] [Related]

  • 9. Assessment of three human in vitro systems in the generation of major human excretory and circulating metabolites.
    Dalvie D, Obach RS, Kang P, Prakash C, Loi CM, Hurst S, Nedderman A, Goulet L, Smith E, Bu HZ, Smith DA.
    Chem Res Toxicol; 2009 Feb 29; 22(2):357-68. PubMed ID: 19146377
    [Abstract] [Full Text] [Related]

  • 10. Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach.
    Ebbels TM, Keun HC, Beckonert OP, Bollard ME, Lindon JC, Holmes E, Nicholson JK.
    J Proteome Res; 2007 Nov 29; 6(11):4407-22. PubMed ID: 17915905
    [Abstract] [Full Text] [Related]

  • 11. A novel ex vivo model system for evaluation of conditionally replicative adenoviruses therapeutic efficacy and toxicity.
    Kirby TO, Rivera A, Rein D, Wang M, Ulasov I, Breidenbach M, Kataram M, Contreras JL, Krumdieck C, Yamamoto M, Rots MG, Haisma HJ, Alvarez RD, Mahasreshti PJ, Curiel DT.
    Clin Cancer Res; 2004 Dec 15; 10(24):8697-703. PubMed ID: 15623655
    [Abstract] [Full Text] [Related]

  • 12. Human hepatocytes: isolation, cryopreservation and applications in drug development.
    Li AP.
    Chem Biol Interact; 2007 May 20; 168(1):16-29. PubMed ID: 17270162
    [Abstract] [Full Text] [Related]

  • 13. Toxicogenomics in drug discovery: from preclinical studies to clinical trials.
    Yang Y, Blomme EA, Waring JF.
    Chem Biol Interact; 2004 Nov 01; 150(1):71-85. PubMed ID: 15522262
    [Abstract] [Full Text] [Related]

  • 14. Hepatocytes--the choice to investigate drug metabolism and toxicity in man: in vitro variability as a reflection of in vivo.
    Gómez-Lechón MJ, Castell JV, Donato MT.
    Chem Biol Interact; 2007 May 20; 168(1):30-50. PubMed ID: 17134688
    [Abstract] [Full Text] [Related]

  • 15. Characterization of ANIT-induced toxicity using precision-cut rat and dog liver slices cultured in a dynamic organ roller system.
    Amin K, Ip C, Sato B, Le T, Green CE, Tyson CA, Behrsing HP.
    Toxicol Pathol; 2006 May 20; 34(6):776-84. PubMed ID: 17162535
    [Abstract] [Full Text] [Related]

  • 16. In silico toxicology for the pharmaceutical sciences.
    Valerio LG.
    Toxicol Appl Pharmacol; 2009 Dec 15; 241(3):356-70. PubMed ID: 19716836
    [Abstract] [Full Text] [Related]

  • 17. Functional human tissue assays.
    Hillier C, Bunton D.
    Drug Discov Today; 2007 May 15; 12(9-10):382-8. PubMed ID: 17467574
    [Abstract] [Full Text] [Related]

  • 18. Safety assessment of drug metabolites: implications of regulatory guidance and potential application of genetically engineered mouse models that express human P450s.
    Powley MW, Frederick CB, Sistare FD, DeGeorge JJ.
    Chem Res Toxicol; 2009 Feb 15; 22(2):257-62. PubMed ID: 19170595
    [Abstract] [Full Text] [Related]

  • 19. Applications of cytotoxicity assays and pre-lethal mechanistic assays for assessment of human hepatotoxicity potential.
    Xu JJ, Diaz D, O'Brien PJ.
    Chem Biol Interact; 2004 Nov 01; 150(1):115-28. PubMed ID: 15522265
    [Abstract] [Full Text] [Related]

  • 20. Accurate prediction of human drug toxicity: a major challenge in drug development.
    Li AP.
    Chem Biol Interact; 2004 Nov 01; 150(1):3-7. PubMed ID: 15522257
    [Abstract] [Full Text] [Related]

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