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Journal Abstract Search
178 related items for PubMed ID: 15522265
1. Applications of cytotoxicity assays and pre-lethal mechanistic assays for assessment of human hepatotoxicity potential. Xu JJ, Diaz D, O'Brien PJ. Chem Biol Interact; 2004 Nov 01; 150(1):115-28. PubMed ID: 15522265 [Abstract] [Full Text] [Related]
2. Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes. Nadanaciva S, Aleo MD, Strock CJ, Stedman DB, Wang H, Will Y. Toxicol Appl Pharmacol; 2013 Oct 15; 272(2):272-80. PubMed ID: 23811329 [Abstract] [Full Text] [Related]
3. Screening for reactive intermediates and toxicity assessment in drug discovery. Caldwell GW, Yan Z. Curr Opin Drug Discov Devel; 2006 Jan 15; 9(1):47-60. PubMed ID: 16445117 [Abstract] [Full Text] [Related]
6. Identification of in vitro protein biomarkers of idiosyncratic liver toxicity. Gao J, Ann Garulacan L, Storm SM, Hefta SA, Opiteck GJ, Lin JH, Moulin F, Dambach DM. Toxicol In Vitro; 2004 Aug 15; 18(4):533-41. PubMed ID: 15130611 [Abstract] [Full Text] [Related]
7. Human hepatocytes: isolation, cryopreservation and applications in drug development. Li AP. Chem Biol Interact; 2007 May 20; 168(1):16-29. PubMed ID: 17270162 [Abstract] [Full Text] [Related]
8. In vitro assays and biomarkers for drug-induced phospholipidosis. Monteith DK, Morgan RE, Halstead B. Expert Opin Drug Metab Toxicol; 2006 Oct 20; 2(5):687-96. PubMed ID: 17014389 [Abstract] [Full Text] [Related]
9. Aroclor 1254 induced cytotoxicity and mitochondrial dysfunction in isolated rat hepatocytes. Aly HA, Domènech O. Toxicology; 2009 Aug 21; 262(3):175-83. PubMed ID: 19486918 [Abstract] [Full Text] [Related]
10. An integrated approach to improved toxicity prediction for the safety assessment during preclinical drug development using Hep G2 cells. Noor F, Niklas J, Müller-Vieira U, Heinzle E. Toxicol Appl Pharmacol; 2009 Jun 01; 237(2):221-31. PubMed ID: 19332084 [Abstract] [Full Text] [Related]
11. Use and application of stem cells in toxicology. Davila JC, Cezar GG, Thiede M, Strom S, Miki T, Trosko J. Toxicol Sci; 2004 Jun 01; 79(2):214-23. PubMed ID: 15014205 [Abstract] [Full Text] [Related]
12. Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials. EFSA GMO Panel Working Group on Animal Feeding Trials. Food Chem Toxicol; 2008 Mar 01; 46 Suppl 1():S2-70. PubMed ID: 18328408 [Abstract] [Full Text] [Related]
13. Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach. Ebbels TM, Keun HC, Beckonert OP, Bollard ME, Lindon JC, Holmes E, Nicholson JK. J Proteome Res; 2007 Nov 01; 6(11):4407-22. PubMed ID: 17915905 [Abstract] [Full Text] [Related]
14. In vitro methods in human drug biotransformation research: implications for cancer chemotherapy. Hariparsad N, Sane RS, Strom SC, Desai PB. Toxicol In Vitro; 2006 Mar 01; 20(2):135-53. PubMed ID: 16359840 [Abstract] [Full Text] [Related]
15. A 96-well flow cytometric screening assay for detecting in vitro phospholipidosis-induction in the drug discovery phase. Natalie M, Margino S, Erik H, Annelieke P, Geert V, Philippe V. Toxicol In Vitro; 2009 Mar 01; 23(2):217-26. PubMed ID: 19101623 [Abstract] [Full Text] [Related]
16. Selection of cytotoxicity markers for the screening of new chemical entities in a pharmaceutical context: a preliminary study using a multiplexing approach. Gerets HH, Hanon E, Cornet M, Dhalluin S, Depelchin O, Canning M, Atienzar FA. Toxicol In Vitro; 2009 Mar 01; 23(2):319-32. PubMed ID: 19110050 [Abstract] [Full Text] [Related]
17. Predictive value of in vitro safety studies. Suter W. Curr Opin Chem Biol; 2006 Aug 01; 10(4):362-6. PubMed ID: 16815733 [Abstract] [Full Text] [Related]