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243 related items for PubMed ID: 1554380

  • 1. A markedly diminished pleiotropic response to phenobarbital and structurally-related xenobiotics in Zucker rats in comparison with F344/NCr or DA rats.
    Lubet RA, Nims RW, Dragnev KH, Jones CR, Diwan BA, Devor DE, Ward JM, Miller MS, Rice JM.
    Biochem Pharmacol; 1992 Mar 03; 43(5):1079-87. PubMed ID: 1554380
    [Abstract] [Full Text] [Related]

  • 2. A pleiotropic response to phenobarbital-type enzyme inducers in the F344/NCr rat. Effects of chemicals of varied structure.
    Lubet RA, Dragnev KH, Chauhan DP, Nims RW, Diwan BA, Ward JM, Jones CR, Rice JM, Miller MS.
    Biochem Pharmacol; 1992 Mar 03; 43(5):1067-78. PubMed ID: 1372805
    [Abstract] [Full Text] [Related]

  • 3. Dose-response relationships for the induction of P450 2B by 1,4-bis[2-(3,5-dichloropyridyloxy)]benzne (TCPOBOP) in rat and cultured rat hepatocytes.
    Nims RW, Sinclair PR, Sinclair JF, Dragnev KH, Jones CR, Mellini DW, Thomas PE, Lubet RA.
    Xenobiotica; 1993 Dec 03; 23(12):1411-26. PubMed ID: 7510916
    [Abstract] [Full Text] [Related]

  • 4. Pharmacodynamics of cytochrome P450 2B induction by phenobarbital, 5-ethyl-5-phenylhydantoin, and 5-ethyl-5-phenyloxazolidinedione in the male rat liver or in cultured rat hepatocytes.
    Nims RW, Sinclair PR, Sinclair JF, Thomas PE, Jones CR, Mellini DW, Syi JL, Lubet RA.
    Chem Res Toxicol; 1993 Dec 03; 6(2):188-96. PubMed ID: 8477010
    [Abstract] [Full Text] [Related]

  • 5. The induction of five rat hepatic P450 cytochromes by phenobarbital and similarly acting compounds is regulated by a sexually dimorphic, dietary-dependent endocrine factor that is highly strain specific.
    Larsen MC, Brake PB, Parmar D, Jefcoate CR.
    Arch Biochem Biophys; 1994 Nov 15; 315(1):24-34. PubMed ID: 7979401
    [Abstract] [Full Text] [Related]

  • 6. P-450 enzyme induction by 5-ethyl-5-phenylhydantoin and 5,5-diethylhydantoin, analogues of barbiturate tumor promoters phenobarbital and barbital, and promotion of liver and thyroid carcinogenesis initiated by N-nitrosodiethylamine in rats.
    Diwan BA, Rice JM, Nims RW, Lubet RA, Hu H, Ward JM.
    Cancer Res; 1988 May 01; 48(9):2492-7. PubMed ID: 3356011
    [Abstract] [Full Text] [Related]

  • 7. Induction of hepatic CYP1A in male F344/NCr rats by dietary exposure to Aroclor 1254: examination of immunochemical, RNA, catalytic, and pharmacokinetic endpoints.
    Nims RW, Beebe LE, Dragnev KH, Thomas PE, Fox SD, Issaq HJ, Jones CR, Lubet RA.
    Environ Res; 1992 Dec 01; 59(2):447-66. PubMed ID: 1281448
    [Abstract] [Full Text] [Related]

  • 8. Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital.
    Xiong H, Yoshinari K, Brouwer KL, Negishi M.
    Drug Metab Dispos; 2002 Aug 01; 30(8):918-23. PubMed ID: 12124310
    [Abstract] [Full Text] [Related]

  • 9. Phenobarbital induction of CYP2B1/2 in primary hepatocytes: endocrine regulation and evidence for a single pathway for multiple inducers.
    Ganem LG, Trottier E, Anderson A, Jefcoate CR.
    Toxicol Appl Pharmacol; 1999 Feb 15; 155(1):32-42. PubMed ID: 10036216
    [Abstract] [Full Text] [Related]

  • 10. Cytochrome P450 2B enzyme induction defect after 2,2',4,4',5,5'-hexachlorobiphenyl treatment in the fa/fa Zucker rat.
    Zannikos PN, Bandyopadhyay AM, Robertson LW, Blouin RA.
    J Pharmacol Exp Ther; 1994 Mar 15; 268(3):1565-70. PubMed ID: 8138968
    [Abstract] [Full Text] [Related]

  • 11. Hepatic cytochrome P450 2B-type induction by ethyl/phenyl-substituted congeners of phenobarbital in the rat.
    Nims RW, Syi JL, Wink DA, Nelson VC, Thomas PE, Jones CR, Diwan BA, Keefer LK, Rice JM, Lubet RA.
    Chem Res Toxicol; 1993 Mar 15; 6(2):180-7. PubMed ID: 8477009
    [Abstract] [Full Text] [Related]

  • 12. Evaluation of octamethylcyclotetrasiloxane (D4) as an inducer of rat hepatic microsomal cytochrome P450, UDP-glucuronosyltransferase, and epoxide hydrolase: a 28-day inhalation study.
    McKim JM, Wilga PC, Kolesar GB, Choudhuri S, Madan A, Dochterman LW, Breen JG, Parkinson A, Mast RW, Meeks RG.
    Toxicol Sci; 1998 Jan 15; 41(1):29-41. PubMed ID: 9520339
    [Abstract] [Full Text] [Related]

  • 13. Modulation of xenobiotic-inducible cytochrome P450 gene expression by dexamethasone in primary rat hepatocytes.
    Sidhu JS, Omiecinski CJ.
    Pharmacogenetics; 1995 Feb 15; 5(1):24-36. PubMed ID: 7773300
    [Abstract] [Full Text] [Related]

  • 14. Regulation of gene expression of various phase I and phase II drug-metabolizing enzymes by tamoxifen in rat liver.
    Hellriegel ET, Matwyshyn GA, Fei P, Dragnev KH, Nims RW, Lubet RA, Kong AN.
    Biochem Pharmacol; 1996 Nov 22; 52(10):1561-8. PubMed ID: 8937471
    [Abstract] [Full Text] [Related]

  • 15. Effects of tamoxifen administration on the expression of xenobiotic metabolizing enzymes in rat liver.
    Nuwaysir EF, Dragan YP, Jefcoate CR, Jordan VC, Pitot HC.
    Cancer Res; 1995 Apr 15; 55(8):1780-6. PubMed ID: 7712488
    [Abstract] [Full Text] [Related]

  • 16. Activation of cytochrome P450 gene expression in the rat brain by phenobarbital-like inducers.
    Schilter B, Andersen MR, Acharya C, Omiecinski CJ.
    J Pharmacol Exp Ther; 2000 Sep 15; 294(3):916-22. PubMed ID: 10945841
    [Abstract] [Full Text] [Related]

  • 17. Phenobarbital induction of cytochromes P-450. High-level long-term responsiveness of primary rat hepatocyte cultures to drug induction, and glucocorticoid dependence of the phenobarbital response.
    Waxman DJ, Morrissey JJ, Naik S, Jauregui HO.
    Biochem J; 1990 Oct 01; 271(1):113-9. PubMed ID: 2222405
    [Abstract] [Full Text] [Related]

  • 18. The chemopreventive agent diallyl sulfide. A structurally atypical phenobarbital-type inducer.
    Dragnev KH, Nims RW, Lubet RA.
    Biochem Pharmacol; 1995 Dec 22; 50(12):2099-104. PubMed ID: 8849338
    [Abstract] [Full Text] [Related]

  • 19. Induction of a pleiotropic response by phenobarbital and related compounds. Response in various inbred strains of rats, response in various species and the induction of aldehyde dehydrogenase in Copenhagen rats.
    Jones CR, Lubet RA.
    Biochem Pharmacol; 1992 Oct 20; 44(8):1651-60. PubMed ID: 1417986
    [Abstract] [Full Text] [Related]

  • 20. Subchronic dietary exposure to Aroclor 1254 in rats: accumulation of PCBs in liver, blood, and adipose tissue and its relationship to induction of various hepatic drug-metabolizing enzymes.
    Dragnev KH, Beebe LE, Jones CR, Fox SD, Thomas PE, Nims RW, Lubet RA.
    Toxicol Appl Pharmacol; 1994 Mar 20; 125(1):111-22. PubMed ID: 7510429
    [Abstract] [Full Text] [Related]

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