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477 related items for PubMed ID: 15547111

  • 1. 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
    Schneider-Stock R, Diab-Assef M, Rohrbeck A, Foltzer-Jourdainne C, Boltze C, Hartig R, Schönfeld P, Roessner A, Gali-Muhtasib H.
    J Pharmacol Exp Ther; 2005 Feb; 312(2):525-36. PubMed ID: 15547111
    [Abstract] [Full Text] [Related]

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  • 3. Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine.
    Deng T, Zhang Y.
    Life Sci; 2009 Feb 27; 84(9-10):311-20. PubMed ID: 19159630
    [Abstract] [Full Text] [Related]

  • 4. 5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia.
    Schmelz K, Wagner M, Dörken B, Tamm I.
    Int J Cancer; 2005 May 01; 114(5):683-95. PubMed ID: 15609309
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  • 5. [Effects of p53 inhibitor-alpha on the proliferation and apoptosis in large intestinal epithelial cells damaged by hyperthermic chemotherapy].
    Zhang AP, Liu BH, Zhang LY, Tong WD, He YJ, Fu T, Luo DL.
    Zhonghua Yi Xue Za Zhi; 2006 Jan 10; 86(2):93-7. PubMed ID: 16620711
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  • 7. Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells.
    Pulukuri SM, Rao JS.
    Int J Oncol; 2005 Apr 10; 26(4):863-71. PubMed ID: 15753979
    [Abstract] [Full Text] [Related]

  • 8. The effects of the DNA methyltranfserases inhibitor 5-Azacitidine on ageing, oxidative stress and DNA methylation of adipose derived stem cells.
    Kornicka K, Marycz K, Marędziak M, Tomaszewski KA, Nicpoń J.
    J Cell Mol Med; 2017 Feb 10; 21(2):387-401. PubMed ID: 27998022
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  • 9. Epigenetic reactivation of RASSF1A by phenethyl isothiocyanate (PEITC) and promotion of apoptosis in LNCaP cells.
    Boyanapalli SS, Li W, Fuentes F, Guo Y, Ramirez CN, Gonzalez XP, Pung D, Kong AN.
    Pharmacol Res; 2016 Dec 10; 114():175-184. PubMed ID: 27818231
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  • 10. Cytotoxicity of 5-Aza-2'-deoxycytidine against gastric cancer involves DNA damage in an ATM-P53 dependent signaling pathway and demethylation of P16(INK4A).
    Liu J, Xie YS, Wang FL, Zhang LJ, Zhang Y, Luo HS.
    Biomed Pharmacother; 2013 Feb 10; 67(1):78-87. PubMed ID: 23201008
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  • 11. 5-Aza-2'-deoxycytidine, a DNA methylation inhibitor, induces cytotoxicity, cell cycle dynamics and alters expression of DNA methyltransferase 1 and 3A in mouse hippocampus-derived neuronal HT22 cells.
    Yang J, Tian X, Yang J, Cui J, Jiang S, Shi R, Liu Y, Liu X, Xu W, Xie W, Jia X, Bade R, Zhang T, Zhang M, Gong K, Yan S, Yang Z, Shao G.
    J Toxicol Environ Health A; 2017 Feb 10; 80(22):1222-1229. PubMed ID: 28880816
    [Abstract] [Full Text] [Related]

  • 12. p21Waf1/Cip1 plays a critical role in modulating senescence through changes of DNA methylation.
    Zheng QH, Ma LW, Zhu WG, Zhang ZY, Tong TJ.
    J Cell Biochem; 2006 Aug 01; 98(5):1230-48. PubMed ID: 16514663
    [Abstract] [Full Text] [Related]

  • 13. 5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status.
    Liu J, Zhang Y, Xie YS, Wang FL, Zhang LJ, Deng T, Luo HS.
    Oncol Rep; 2012 Aug 01; 28(2):545-52. PubMed ID: 22664909
    [Abstract] [Full Text] [Related]

  • 14. Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer.
    Chen W, Gao N, Shen Y, Cen JN.
    J Gastroenterol Hepatol; 2010 Apr 01; 25(4):823-31. PubMed ID: 20492341
    [Abstract] [Full Text] [Related]

  • 15. Simultaneous inhibition of DNA methyltransferase and histone deacetylase induces p53-independent apoptosis via down-regulation of Mcl-1 in acute myelogenous leukemia cells.
    Nishioka C, Ikezoe T, Yang J, Udaka K, Yokoyama A.
    Leuk Res; 2011 Jul 01; 35(7):932-9. PubMed ID: 21550660
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  • 16. [Apoptosis and re-expression of p16 gene in the myeloma cell line U266 induced by synergy of histone deacetylase inhibitor and demethylating agent].
    Du HL, Qi Y, Shi YJ, Bu DF, Wu SL.
    Ai Zheng; 2002 Oct 01; 21(10):1057-61. PubMed ID: 12508642
    [Abstract] [Full Text] [Related]

  • 17. [Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines].
    Chen YX, Fang JY, Lu J, Qiu DK.
    Zhonghua Yi Xue Za Zhi; 2004 Feb 17; 84(4):312-7. PubMed ID: 15059516
    [Abstract] [Full Text] [Related]

  • 18. Down-regulation of p16 and MGMT promotes the anti-proliferative and pro-apoptotic effects of 5-Aza-dC and radiation on cervical cancer cells.
    Chen GD, Qian DY, Li ZG, Fan GY, You KL, Wu YL.
    Cell Biochem Funct; 2017 Dec 17; 35(8):488-496. PubMed ID: 29143344
    [Abstract] [Full Text] [Related]

  • 19. Epigenetic mechanisms of irinotecan sensitivity in colorectal cancer cell lines.
    Crea F, Giovannetti E, Cortesi F, Mey V, Nannizzi S, Gallegos Ruiz MI, Ricciardi S, Del Tacca M, Peters GJ, Danesi R.
    Mol Cancer Ther; 2009 Jul 17; 8(7):1964-73. PubMed ID: 19531575
    [Abstract] [Full Text] [Related]

  • 20. Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15.
    Ishiguro M, Iida S, Uetake H, Morita S, Makino H, Kato K, Takagi Y, Enomoto M, Sugihara K.
    Ann Surg Oncol; 2007 May 17; 14(5):1752-62. PubMed ID: 17195906
    [Abstract] [Full Text] [Related]

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