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635 related items for PubMed ID: 15548589

  • 1. Intracellular Abeta42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease.
    Ohyagi Y, Asahara H, Chui DH, Tsuruta Y, Sakae N, Miyoshi K, Yamada T, Kikuchi H, Taniwaki T, Murai H, Ikezoe K, Furuya H, Kawarabayashi T, Shoji M, Checler F, Iwaki T, Makifuchi T, Takeda K, Kira J, Tabira T.
    FASEB J; 2005 Feb; 19(2):255-7. PubMed ID: 15548589
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  • 6. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
    Majercak J, Ray WJ, Espeseth A, Simon A, Shi XP, Wolffe C, Getty K, Marine S, Stec E, Ferrer M, Strulovici B, Bartz S, Gates A, Xu M, Huang Q, Ma L, Shughrue P, Burchard J, Colussi D, Pietrak B, Kahana J, Beher D, Rosahl T, Shearman M, Hazuda D, Sachs AB, Koblan KS, Seabrook GR, Stone DJ.
    Proc Natl Acad Sci U S A; 2006 Nov 21; 103(47):17967-72. PubMed ID: 17098871
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  • 8. Overexpression of amyloid precursor protein is associated with degeneration, decreased viability, and increased damage caused by neurotoxins (prostaglandins A1 and E2, hydrogen peroxide, and nitric oxide) in differentiated neuroblastoma cells.
    Hanson AJ, Prasad JE, Nahreini P, Andreatta C, Kumar B, Yan XD, Prasad KN.
    J Neurosci Res; 2003 Oct 01; 74(1):148-59. PubMed ID: 13130517
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  • 9. Interaction between NH(2)-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deterioration.
    Amadoro G, Corsetti V, Atlante A, Florenzano F, Capsoni S, Bussani R, Mercanti D, Calissano P.
    Neurobiol Aging; 2012 Apr 01; 33(4):833.e1-25. PubMed ID: 21958963
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  • 10. Alzheimer's disease amyloid β-protein mutations and deletions that define neuronal binding/internalization as early stage nonfibrillar/fibrillar aggregates and late stage fibrils.
    Poduslo JF, Howell KG, Olson NC, Ramirez-Alvarado M, Kandimalla KK.
    Biochemistry; 2012 May 15; 51(19):3993-4003. PubMed ID: 22545812
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  • 11. Impaired neuronal insulin signaling precedes Aβ42 accumulation in female AβPPsw/PS1ΔE9 mice.
    Chua LM, Lim ML, Chong PR, Hu ZP, Cheung NS, Wong BS.
    J Alzheimers Dis; 2012 May 15; 29(4):783-91. PubMed ID: 22337827
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  • 12. Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells.
    Ramalho RM, Borralho PM, Castro RE, Solá S, Steer CJ, Rodrigues CM.
    J Neurochem; 2006 Sep 15; 98(5):1610-8. PubMed ID: 16923170
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  • 13. [The beta-amyloid cascade hypothesis: a sequence of events leading to neurodegeneration in Alzheimer's disease].
    Kowalska A.
    Neurol Neurochir Pol; 2004 Sep 15; 38(5):405-11. PubMed ID: 15565529
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  • 14. The calcineurin inhibitor Sarah (Nebula) exacerbates Aβ42 phenotypes in a Drosophila model of Alzheimer's disease.
    Lee S, Bang SM, Hong YK, Lee JH, Jeong H, Park SH, Liu QF, Lee IS, Cho KS.
    Dis Model Mech; 2016 Mar 15; 9(3):295-306. PubMed ID: 26659252
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  • 15. Effects of a tacrine-8-hydroxyquinoline hybrid (IQM-622) on Aβ accumulation and cell death: involvement in hippocampal neuronal loss in Alzheimer's disease.
    Antequera D, Bolos M, Spuch C, Pascual C, Ferrer I, Fernandez-Bachiller MI, Rodríguez-Franco MI, Carro E.
    Neurobiol Dis; 2012 Jun 15; 46(3):682-91. PubMed ID: 22426395
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  • 16. Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease.
    Iijima K, Liu HP, Chiang AS, Hearn SA, Konsolaki M, Zhong Y.
    Proc Natl Acad Sci U S A; 2004 Apr 27; 101(17):6623-8. PubMed ID: 15069204
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  • 17. Intracellular accumulation of toxic turn amyloid-β is associated with endoplasmic reticulum stress in Alzheimer's disease.
    Soejima N, Ohyagi Y, Nakamura N, Himeno E, Iinuma KM, Sakae N, Yamasaki R, Tabira T, Murakami K, Irie K, Kinoshita N, LaFerla FM, Kiyohara Y, Iwaki T, Kira J.
    Curr Alzheimer Res; 2013 Jan 27; 10(1):11-20. PubMed ID: 22950910
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  • 18. Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells.
    Esposito L, Gan L, Yu GQ, Essrich C, Mucke L.
    J Neurochem; 2004 Dec 27; 91(6):1260-74. PubMed ID: 15584903
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  • 19. mTOR/p70S6k signalling alteration by Abeta exposure as well as in APP-PS1 transgenic models and in patients with Alzheimer's disease.
    Lafay-Chebassier C, Paccalin M, Page G, Barc-Pain S, Perault-Pochat MC, Gil R, Pradier L, Hugon J.
    J Neurochem; 2005 Jul 27; 94(1):215-25. PubMed ID: 15953364
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  • 20. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.
    J Neurosci Res; 2002 Aug 15; 69(4):530-9. PubMed ID: 12210846
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