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Journal Abstract Search

279 related items for PubMed ID: 15553924

  • 1. Sulfonate ester hydroxamic acids as potent and selective inhibitors of TACE enzyme.
    Levin JI, Du MT.
    Drug Des Discov; 2003; 18(4):123-6. PubMed ID: 15553924
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  • 4. Discovery of selective hydroxamic acid inhibitors of tumor necrosis factor-alpha converting enzyme.
    Holms J, Mast K, Marcotte P, Elmore I, Li J, Pease L, Glaser K, Morgan D, Michaelides M, Davidsen S.
    Bioorg Med Chem Lett; 2001 Nov 19; 11(22):2907-10. PubMed ID: 11677124
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  • 5. Chromen-based TNF-alpha converting enzyme (TACE) inhibitors: design, synthesis, and biological evaluation.
    Chun K, Park SK, Kim HM, Choi Y, Kim MH, Park CH, Joe BY, Chun TG, Choi HM, Lee HY, Hong SH, Kim MS, Nam KY, Han G.
    Bioorg Med Chem; 2008 Jan 01; 16(1):530-5. PubMed ID: 17936631
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  • 8. The design and synthesis of aryl hydroxamic acid inhibitors of MMPs and TACE.
    Levin JI.
    Curr Top Med Chem; 2004 Jan 01; 4(12):1289-310. PubMed ID: 15320727
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  • 10. Benzodiazepine inhibitors of the MMPs and TACE. Part 2.
    Levin JI, Nelson FC, Delos Santos E, Du MT, MacEwan G, Chen JM, Ayral-Kaloustian S, Xu J, Jin G, Cummons T, Barone D.
    Bioorg Med Chem Lett; 2004 Aug 16; 14(16):4147-51. PubMed ID: 15261259
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  • 12. Synthesis and structure-activity relationships of 4-alkynyloxy phenyl sulfanyl, sulfinyl, and sulfonyl alkyl hydroxamates as tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase inhibitors.
    Venkatesan AM, Davis JM, Grosu GT, Baker J, Zask A, Levin JI, Ellingboe J, Skotnicki JS, Dijoseph JF, Sung A, Jin G, Xu W, McCarthy DJ, Barone D.
    J Med Chem; 2004 Dec 02; 47(25):6255-69. PubMed ID: 15566296
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  • 13. Structure-based design of TACE selective inhibitors: manipulations in the S1'-S3' pocket.
    Huang A, Joseph-McCarthy D, Lovering F, Sun L, Wang W, Xu W, Zhu Y, Cui J, Zhang Y, Levin JI.
    Bioorg Med Chem; 2007 Sep 15; 15(18):6170-81. PubMed ID: 17606376
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  • 14. Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors.
    Zask A, Gu Y, Albright JD, Du X, Hogan M, Levin JI, Chen JM, Killar LM, Sung A, DiJoseph JF, Sharr MA, Roth CE, Skala S, Jin G, Cowling R, Mohler KM, Barone D, Black R, March C, Skotnicki JS.
    Bioorg Med Chem Lett; 2003 Apr 17; 13(8):1487-90. PubMed ID: 12668018
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  • 16. Benzodiazepine inhibitors of the MMPs and TACE.
    Nelson FC, Delos Santos E, Levin JI, Chen JM, Skotnicki JS, DiJoseph JF, Sharr MA, Sung A, Killar LM, Cowling R, Jin G, Roth CE, Albright JD.
    Bioorg Med Chem Lett; 2002 Oct 21; 12(20):2867-70. PubMed ID: 12270165
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  • 17. Discovery of gamma-lactam hydroxamic acids as selective inhibitors of tumor necrosis factor alpha converting enzyme: design, synthesis, and structure-activity relationships.
    Duan JJ, Chen L, Wasserman ZR, Lu Z, Liu RQ, Covington MB, Qian M, Hardman KD, Magolda RL, Newton RC, Christ DD, Wexler RR, Decicco CP.
    J Med Chem; 2002 Nov 07; 45(23):4954-7. PubMed ID: 12408705
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  • 20. Acetylenic TACE inhibitors. Part 3: Thiomorpholine sulfonamide hydroxamates.
    Levin JI, Chen JM, Laakso LM, Du M, Schmid J, Xu W, Cummons T, Xu J, Jin G, Barone D, Skotnicki JS.
    Bioorg Med Chem Lett; 2006 Mar 15; 16(6):1605-9. PubMed ID: 16426848
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