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Journal Abstract Search

231 related items for PubMed ID: 15561722

  • 1. Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels.
    Perraud AL, Takanishi CL, Shen B, Kang S, Smith MK, Schmitz C, Knowles HM, Ferraris D, Li W, Zhang J, Stoddard BL, Scharenberg AM.
    J Biol Chem; 2005 Feb 18; 280(7):6138-48. PubMed ID: 15561722
    [Abstract] [Full Text] [Related]

  • 2. Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2.
    Kühn FJ, Lückhoff A.
    J Biol Chem; 2004 Nov 05; 279(45):46431-7. PubMed ID: 15347676
    [Abstract] [Full Text] [Related]

  • 3. Ligand-induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg1433 and Tyr1349.
    Fliegert R, Watt JM, Schöbel A, Rozewitz MD, Moreau C, Kirchberger T, Thomas MP, Sick W, Araujo AC, Harneit A, Potter BVL, Guse AH.
    Biochem J; 2017 Jun 16; 474(13):2159-2175. PubMed ID: 28515263
    [Abstract] [Full Text] [Related]

  • 4. TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase.
    Fonfria E, Marshall IC, Benham CD, Boyfield I, Brown JD, Hill K, Hughes JP, Skaper SD, McNulty S.
    Br J Pharmacol; 2004 Sep 16; 143(1):186-92. PubMed ID: 15302683
    [Abstract] [Full Text] [Related]

  • 5. The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes.
    Buelow B, Song Y, Scharenberg AM.
    J Biol Chem; 2008 Sep 05; 283(36):24571-83. PubMed ID: 18599483
    [Abstract] [Full Text] [Related]

  • 6. TRPM2 Ca2+ permeable cation channels: from gene to biological function.
    Perraud AL, Schmitz C, Scharenberg AM.
    Cell Calcium; 2003 Sep 05; 33(5-6):519-31. PubMed ID: 12765697
    [Abstract] [Full Text] [Related]

  • 7. The Role of TRPM2 in Endothelial Function and Dysfunction.
    Zielińska W, Zabrzyński J, Gagat M, Grzanka A.
    Int J Mol Sci; 2021 Jul 16; 22(14):. PubMed ID: 34299254
    [Abstract] [Full Text] [Related]

  • 8. TRPM2 and TRPM7: channel/enzyme fusions to generate novel intracellular sensors.
    Scharenberg AM.
    Pflugers Arch; 2005 Oct 16; 451(1):220-7. PubMed ID: 16001276
    [Abstract] [Full Text] [Related]

  • 9. ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology.
    Perraud AL, Fleig A, Dunn CA, Bagley LA, Launay P, Schmitz C, Stokes AJ, Zhu Q, Bessman MJ, Penner R, Kinet JP, Scharenberg AM.
    Nature; 2001 May 31; 411(6837):595-9. PubMed ID: 11385575
    [Abstract] [Full Text] [Related]

  • 10. Cyclic ADP-ribose and hydrogen peroxide synergize with ADP-ribose in the activation of TRPM2 channels.
    Kolisek M, Beck A, Fleig A, Penner R.
    Mol Cell; 2005 Apr 01; 18(1):61-9. PubMed ID: 15808509
    [Abstract] [Full Text] [Related]

  • 11. TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose.
    Kühn FJ, Heiner I, Lückhoff A.
    Pflugers Arch; 2005 Oct 01; 451(1):212-9. PubMed ID: 15952035
    [Abstract] [Full Text] [Related]

  • 12. Hypericum perforatum Attenuates Spinal Cord Injury-Induced Oxidative Stress and Apoptosis in the Dorsal Root Ganglion of Rats: Involvement of TRPM2 and TRPV1 Channels.
    Özdemir ÜS, Nazıroğlu M, Şenol N, Ghazizadeh V.
    Mol Neurobiol; 2016 Aug 01; 53(6):3540-3551. PubMed ID: 26099309
    [Abstract] [Full Text] [Related]

  • 13. New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose.
    Naziroğlu M.
    Neurochem Res; 2007 Nov 01; 32(11):1990-2001. PubMed ID: 17562166
    [Abstract] [Full Text] [Related]

  • 14. Structures and gating mechanism of human TRPM2.
    Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H.
    Science; 2018 Dec 21; 362(6421):. PubMed ID: 30467180
    [Abstract] [Full Text] [Related]

  • 15. Pore collapse underlies irreversible inactivation of TRPM2 cation channel currents.
    Tóth B, Csanády L.
    Proc Natl Acad Sci U S A; 2012 Aug 14; 109(33):13440-5. PubMed ID: 22847436
    [Abstract] [Full Text] [Related]

  • 16. ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain.
    Kühn FJ, Kühn C, Winking M, Hoffmann DC, Lückhoff A.
    PLoS One; 2016 Aug 14; 11(6):e0158060. PubMed ID: 27333281
    [Abstract] [Full Text] [Related]

  • 17. Direct Gating of the TRPM2 Channel by cADPR via Specific Interactions with the ADPR Binding Pocket.
    Yu P, Liu Z, Yu X, Ye P, Liu H, Xue X, Yang L, Li Z, Wu Y, Fang C, Zhao YJ, Yang F, Luo JH, Jiang LH, Zhang L, Zhang L, Yang W.
    Cell Rep; 2019 Jun 18; 27(12):3684-3695.e4. PubMed ID: 31216484
    [Abstract] [Full Text] [Related]

  • 18. Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium.
    Huang Y, Winkler PA, Sun W, Lü W, Du J.
    Nature; 2018 Oct 18; 562(7725):145-149. PubMed ID: 30250252
    [Abstract] [Full Text] [Related]

  • 19. The Protective Role of Selenium on Scopolamine-Induced Memory Impairment, Oxidative Stress, and Apoptosis in Aged Rats: The Involvement of TRPM2 and TRPV1 Channels.
    Balaban H, Nazıroğlu M, Demirci K, Övey İS.
    Mol Neurobiol; 2017 May 18; 54(4):2852-2868. PubMed ID: 27021021
    [Abstract] [Full Text] [Related]

  • 20. Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8.
    Kühn FJP, Witschas K, Kühn C, Lückhoff A.
    J Biol Chem; 2010 Aug 27; 285(35):26806-26814. PubMed ID: 20587417
    [Abstract] [Full Text] [Related]

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