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144 related items for PubMed ID: 15566096

  • 1. Comparison of hepatic in vitro metabolism of the pyrrolizidine alkaloid senecionine in sheep and cattle.
    Duringer JM, Buhler DR, Craig AM.
    Am J Vet Res; 2004 Nov; 65(11):1563-72. PubMed ID: 15566096
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  • 3. Human liver microsomal reduction of pyrrolizidine alkaloid N-oxides to form the corresponding carcinogenic parent alkaloid.
    Wang YP, Yan J, Fu PP, Chou MW.
    Toxicol Lett; 2005 Mar 15; 155(3):411-20. PubMed ID: 15649625
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  • 5. The roles of CYP3A and CYP2B isoforms in hepatic bioactivation and detoxification of the pyrrolizidine alkaloid senecionine in sheep and hamsters.
    Huan JY, Miranda CL, Buhler DR, Cheeke PR.
    Toxicol Appl Pharmacol; 1998 Aug 15; 151(2):229-35. PubMed ID: 9707499
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  • 7. Species differences in the hepatic microsomal metabolism of the pyrrolizidine alkaloid senecionine.
    Winter CK, Segall HJ, Jones AD.
    Comp Biochem Physiol C Comp Pharmacol Toxicol; 1988 Aug 15; 90(2):429-33. PubMed ID: 2903002
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  • 8. Microsomal formation of a pyrrolic alcohol glutathione conjugate of the pyrrolizidine alkaloid senecionine.
    Reed RL, Miranda CL, Kedzierski B, Henderson MC, Buhler DR.
    Xenobiotica; 1992 Nov 15; 22(11):1321-7. PubMed ID: 1492424
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  • 9. Formation of DHP-derived DNA adducts from metabolic activation of the prototype heliotridine-type pyrrolizidine alkaloid, heliotrine.
    Xia Q, Yan J, Chou MW, Fu PP.
    Toxicol Lett; 2008 May 05; 178(2):77-82. PubMed ID: 18395999
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  • 10. New glutathione conjugate of pyrrolizidine alkaloids produced by human cytosolic enzyme-dependent reactions in vitro.
    Muluneh F, Häkkinen MR, El-Dairi R, Pasanen M, Juvonen RO.
    Rapid Commun Mass Spectrom; 2018 Aug 30; 32(16):1344-1352. PubMed ID: 29788543
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  • 11. Differential metabolism of the pyrrolizidine alkaloid, senecionine, in Fischer 344 and Sprague-Dawley rats.
    Chung WG, Buhler DR.
    Arch Pharm Res; 2004 May 30; 27(5):547-53. PubMed ID: 15202562
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  • 12. Flavin-containing monooxygenase: a major detoxifying enzyme for the pyrrolizidine alkaloid senecionine in guinea pig tissues.
    Miranda CL, Chung W, Reed RE, Zhao X, Henderson MC, Wang JL, Williams DE, Buhler DR.
    Biochem Biophys Res Commun; 1991 Jul 31; 178(2):546-52. PubMed ID: 1907134
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  • 13. Riddelliine N-oxide is a phytochemical and mammalian metabolite with genotoxic activity that is comparable to the parent pyrrolizidine alkaloid riddelliine.
    Chou MW, Wang YP, Yan J, Yang YC, Beger RD, Williams LD, Doerge DR, Fu PP.
    Toxicol Lett; 2003 Dec 10; 145(3):239-47. PubMed ID: 14580895
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  • 15. Bioactivation and detoxication of the pyrrolizidine alkaloid senecionine by cytochrome P-450 enzymes in rat liver.
    Williams DE, Reed RL, Kedzierski B, Dannan GA, Guengerich FP, Buhler DR.
    Drug Metab Dispos; 1989 Dec 10; 17(4):387-92. PubMed ID: 2571477
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  • 16. 7-cysteine-pyrrole conjugate: A new potential DNA reactive metabolite of pyrrolizidine alkaloids.
    He X, Xia Q, Ma L, Fu PP.
    J Environ Sci Health C Environ Carcinog Ecotoxicol Rev; 2016 Dec 10; 34(1):57-76. PubMed ID: 26761716
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  • 20. The formation of 6,7-dihydro-7-hydroxy-1-hydroxy-methyl-5H-pyrrolizine, a metabolite of pyrrolizidine alkaloids.
    Kedzierski B, Buhler DR.
    Chem Biol Interact; 1986 Feb 10; 57(2):217-22. PubMed ID: 3955792
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