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Journal Abstract Search
214 related items for PubMed ID: 15566303
21. A comparison of physicochemical property profiles of marketed oral drugs and orally bioavailable anti-cancer protein kinase inhibitors in clinical development. Gill AL, Verdonk M, Boyle RG, Taylor R. Curr Top Med Chem; 2007; 7(14):1408-22. PubMed ID: 17692029 [Abstract] [Full Text] [Related]
23. In silico prediction of the solubility advantage for amorphous drugs - Are there property-based rules for drug discovery and early pharmaceutical development? Kuentz M, Imanidis G. Eur J Pharm Sci; 2013 Feb 14; 48(3):554-62. PubMed ID: 23262058 [Abstract] [Full Text] [Related]
25. Intramolecular hydrogen bonding in medicinal chemistry. Kuhn B, Mohr P, Stahl M. J Med Chem; 2010 Mar 25; 53(6):2601-11. PubMed ID: 20175530 [Abstract] [Full Text] [Related]
26. In silico model of drug permeability across sublingual mucosa. Goswami T, Kokate A, Jasti BR, Li X. Arch Oral Biol; 2013 May 25; 58(5):545-51. PubMed ID: 23123066 [Abstract] [Full Text] [Related]
27. Dependence of molecular properties on proteomic family for marketed oral drugs. Vieth M, Sutherland JJ. J Med Chem; 2006 Jun 15; 49(12):3451-3. PubMed ID: 16759087 [Abstract] [Full Text] [Related]
29. The graphical representation of ADME-related molecule properties for medicinal chemists. Ritchie TJ, Ertl P, Lewis R. Drug Discov Today; 2011 Jan 15; 16(1-2):65-72. PubMed ID: 21074634 [Abstract] [Full Text] [Related]
31. Relationships between the release of soluble drugs from HPMC matrices and the physicochemical properties of drugs. Fu XC, Liang WQ, Ma WX. Pharmazie; 2003 Mar 15; 58(3):221-2. PubMed ID: 12685821 [No Abstract] [Full Text] [Related]
35. Prediction of drug solubility from molecular structure using a drug-like training set. Huuskonen J, Livingstone DJ, Manallack DT. SAR QSAR Environ Res; 2008 Mar 15; 19(3-4):191-212. PubMed ID: 18484495 [Abstract] [Full Text] [Related]
37. The role of ligand efficiency metrics in drug discovery. Hopkins AL, Keserü GM, Leeson PD, Rees DC, Reynolds CH. Nat Rev Drug Discov; 2014 Feb 15; 13(2):105-21. PubMed ID: 24481311 [Abstract] [Full Text] [Related]
38. The hydrophobic effect. 2. Relative importance of the hydrophobic effect on the solubility of hydrophobes and pharmaceuticals in H-bonded solvents. Ruelle P, Kesselring UW. J Pharm Sci; 1998 Aug 15; 87(8):998-1014. PubMed ID: 9687345 [Abstract] [Full Text] [Related]