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109 related items for PubMed ID: 15569412

  • 1. Establishment of liver specific glucokinase gene knockout mice: a new animal model for screening anti-diabetic drugs.
    Zhang YL, Tan XH, Xiao MF, Li H, Mao YQ, Yang X, Tan HR.
    Acta Pharmacol Sin; 2004 Dec; 25(12):1659-65. PubMed ID: 15569412
    [Abstract] [Full Text] [Related]

  • 2. Construction of engineered murine embryonic stem cells with conditional knockout of FGFR2 depending on Cre-loxP.
    Jianmin W, Ruihua S, Lei C, Liangjun Y, Bo C, Jing S, Yuanbing G, Ling Z, Lin C.
    Biocell; 2006 Aug; 30(2):269-78. PubMed ID: 16972551
    [Abstract] [Full Text] [Related]

  • 3. Improved metabolic disorders of insulin receptor-deficient mice by transgenic overexpression of glucokinase in the liver.
    Jackerott M, Baudry A, Bucchini D, Jami J, Joshi RL.
    Diabetologia; 2002 Sep; 45(9):1292-7. PubMed ID: 12242462
    [Abstract] [Full Text] [Related]

  • 4. A series of maturity onset diabetes of the young, type 2 (MODY2) mouse models generated by a large-scale ENU mutagenesis program.
    Inoue M, Sakuraba Y, Motegi H, Kubota N, Toki H, Matsui J, Toyoda Y, Miwa I, Terauchi Y, Kadowaki T, Shigeyama Y, Kasuga M, Adachi T, Fujimoto N, Matsumoto R, Tsuchihashi K, Kagami T, Inoue A, Kaneda H, Ishijima J, Masuya H, Suzuki T, Wakana S, Gondo Y, Minowa O, Shiroishi T, Noda T.
    Hum Mol Genet; 2004 Jun 01; 13(11):1147-57. PubMed ID: 15102714
    [Abstract] [Full Text] [Related]

  • 5. Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase.
    Postic C, Shiota M, Niswender KD, Jetton TL, Chen Y, Moates JM, Shelton KD, Lindner J, Cherrington AD, Magnuson MA.
    J Biol Chem; 1999 Jan 01; 274(1):305-15. PubMed ID: 9867845
    [Abstract] [Full Text] [Related]

  • 6. Reversal of type 1 diabetes by engineering a glucose sensor in skeletal muscle.
    Mas A, Montané J, Anguela XM, Muñoz S, Douar AM, Riu E, Otaegui P, Bosch F.
    Diabetes; 2006 Jun 01; 55(6):1546-53. PubMed ID: 16731816
    [Abstract] [Full Text] [Related]

  • 7. Recent advances in glucokinase activators for the treatment of type 2 diabetes.
    Pal M.
    Drug Discov Today; 2009 Aug 01; 14(15-16):784-92. PubMed ID: 19520181
    [Abstract] [Full Text] [Related]

  • 8. [Role of glucokinase (GK) in the maintenance of glucose homeostasis. Specific disruption of the gene by the Cre-loxP technique].
    Postic C, Magnuson MA.
    Journ Annu Diabetol Hotel Dieu; 1999 Aug 01; ():115-24. PubMed ID: 10732411
    [No Abstract] [Full Text] [Related]

  • 9. Effects of bis(alpha-furancarboxylato)oxovanadium(IV) on glucose metabolism in fat-fed/streptozotocin-diabetic rats.
    Niu Y, Liu W, Tian C, Xie M, Gao L, Chen Z, Chen X, Li L.
    Eur J Pharmacol; 2007 Oct 31; 572(2-3):213-9. PubMed ID: 17651728
    [Abstract] [Full Text] [Related]

  • 10. Knockout mice challenge our concepts of glucose homeostasis and the pathogenesis of diabetes.
    Kahn CR.
    Exp Diabesity Res; 2003 Oct 31; 4(3):169-82. PubMed ID: 15061645
    [Abstract] [Full Text] [Related]

  • 11. Knock-out mouse for Canavan disease: a model for gene transfer to the central nervous system.
    Matalon R, Rady PL, Platt KA, Skinner HB, Quast MJ, Campbell GA, Matalon K, Ceci JD, Tyring SK, Nehls M, Surendran S, Wei J, Ezell EL, Szucs S.
    J Gene Med; 2000 Oct 31; 2(3):165-75. PubMed ID: 10894262
    [Abstract] [Full Text] [Related]

  • 12. Astragalus polysaccharide reduces hepatic endoplasmic reticulum stress and restores glucose homeostasis in a diabetic KKAy mouse model.
    Mao XQ, Wu Y, Wu K, Liu M, Zhang JF, Zou F, Ou-Yang JP.
    Acta Pharmacol Sin; 2007 Dec 31; 28(12):1947-56. PubMed ID: 18031609
    [Abstract] [Full Text] [Related]

  • 13. Increased glucose production in mice overexpressing human fructose-1,6-bisphosphatase in the liver.
    Visinoni S, Fam BC, Blair A, Rantzau C, Lamont BJ, Bouwman R, Watt MJ, Proietto J, Favaloro JM, Andrikopoulos S.
    Am J Physiol Endocrinol Metab; 2008 Nov 31; 295(5):E1132-41. PubMed ID: 18780768
    [Abstract] [Full Text] [Related]

  • 14. Ontogenetic characteristics of enzyme activities and plasma metabolites in C57BL/6J:Jcl mice deficient in insulin receptor substrate 2.
    Hashimoto H, Arai T, Takeguchi A, Hioki K, Ohnishi Y, Kawai K, Ito M, Suzuki R, Yamauchi T, Ohsugi M, Saito M, Ueyama Y, Tobe K, Kadowaki T, Tamaoki N, Kosaka K.
    Comp Med; 2006 Jun 31; 56(3):176-87. PubMed ID: 16774126
    [Abstract] [Full Text] [Related]

  • 15. Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.
    Farrelly D, Brown KS, Tieman A, Ren J, Lira SA, Hagan D, Gregg R, Mookhtiar KA, Hariharan N.
    Proc Natl Acad Sci U S A; 1999 Dec 07; 96(25):14511-6. PubMed ID: 10588736
    [Abstract] [Full Text] [Related]

  • 16. Targeted disruption of the hepatic transferrin receptor 2 gene in mice leads to iron overload.
    Wallace DF, Summerville L, Subramaniam VN.
    Gastroenterology; 2007 Jan 07; 132(1):301-10. PubMed ID: 17241880
    [Abstract] [Full Text] [Related]

  • 17. Glucose toxicity is responsible for the development of impaired regulation of endogenous glucose production and hepatic glucokinase in Zucker diabetic fatty rats.
    Fujimoto Y, Torres TP, Donahue EP, Shiota M.
    Diabetes; 2006 Sep 07; 55(9):2479-90. PubMed ID: 16936196
    [Abstract] [Full Text] [Related]

  • 18. Roles of hepatic glucokinase in intertissue metabolic communication: Examination of novel liver-specific glucokinase knockout mice.
    Hayashi H, Sato Y, Li Z, Yamamura K, Yoshizawa T, Yamagata K.
    Biochem Biophys Res Commun; 2015 May 08; 460(3):727-32. PubMed ID: 25817793
    [Abstract] [Full Text] [Related]

  • 19. Glucokinase in chicken (Gallus gallus). Partial cDNA cloning, immunodetection and activity determination.
    Berradi H, Taouis M, Cassy S, Rideau N.
    Comp Biochem Physiol B Biochem Mol Biol; 2005 Jun 08; 141(2):129-39. PubMed ID: 15878833
    [Abstract] [Full Text] [Related]

  • 20. Variable expression of hepatic glucokinase in mice is due to a regulational locus that cosegregates with the glucokinase gene.
    Moates JM, Postic C, Decaux JF, Girard J, Magnuson MA.
    Genomics; 1997 Oct 01; 45(1):185-93. PubMed ID: 9339375
    [Abstract] [Full Text] [Related]

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