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PUBMED FOR HANDHELDS

Journal Abstract Search


219 related items for PubMed ID: 15575685

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  • 7. Phe-Aib hydroxyethylene dipeptide isostere synthesis.
    Genest N, Del Valle S, Lama T, Lubell WD.
    Adv Exp Med Biol; 2009; 611():221-2. PubMed ID: 19400169
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  • 8. Synthesis of Tic-D-Phe Psi[CH2-CH2] isostere and its use in the development of melanocortin receptor agonists.
    Tian X, Chen X, Gan L, Hayes JC, Switzer AG, Solinsky MG, Ebetino FH, Wos JA, Pinney BB, Farmer JA, Crossdoersen D, Sheldon RJ.
    Bioorg Med Chem Lett; 2006 Mar 15; 16(6):1721-5. PubMed ID: 16376076
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  • 9. Preorganization of the hydroxyethylene dipeptide isostere: the preferred conformation in solution resembles the conformation bound to BACE.
    Vidal P, Timm D, Broughton H, Chen SH, Martín JA, Rivera-Sagredo A, McCarthy JR, Shapiro MJ, Espinosa JF.
    J Med Chem; 2005 Dec 01; 48(24):7623-7. PubMed ID: 16302802
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  • 10. An efficient, stereoselective synthesis of the hydroxyethylene dipeptide isostere core for the HIV protease inhibitor A-792611.
    Engstrom K, Henry R, Hollis LS, Kotecki B, Marsden I, Pu YM, Wagaw S, Wang W.
    J Org Chem; 2006 Jul 07; 71(14):5369-72. PubMed ID: 16808529
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  • 12. Design and synthesis of hydroxyethylene-based peptidomimetic inhibitors of human beta-secretase.
    Hom RK, Gailunas AF, Mamo S, Fang LY, Tung JS, Walker DE, Davis D, Thorsett ED, Jewett NE, Moon JB, John V.
    J Med Chem; 2004 Jan 01; 47(1):158-64. PubMed ID: 14695829
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  • 13. HIV-1 protease inhibitors based on hydroxyethylene dipeptide isosteres: an investigation into the role of the P1' side chain on structure-activity.
    Young SD, Payne LS, Thompson WJ, Gaffin N, Lyle TA, Britcher SF, Graham SL, Schultz TH, Deana AA, Darke PL.
    J Med Chem; 1992 May 15; 35(10):1702-9. PubMed ID: 1588552
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  • 14. Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1.
    Yang W, Lu W, Lu Y, Zhong M, Sun J, Thomas AE, Wilkinson JM, Fucini RV, Lam M, Randal M, Shi XP, Jacobs JW, McDowell RS, Gordon EM, Ballinger MD.
    J Med Chem; 2006 Feb 09; 49(3):839-42. PubMed ID: 16451048
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  • 16. Stereocontrolled synthesis of psi[CH = CH] dipeptide isosteres.
    Kempf DJ, Wang XC, Spanton SG.
    Int J Pept Protein Res; 1991 Sep 09; 38(3):237-41. PubMed ID: 1761370
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  • 20. Design, synthesis, and evaluation of Leu*Ala hydroxyethylene-based non-peptide beta-secretase (BACE) inhibitors.
    Xiao K, Li X, Li J, Ma L, Hu B, Yu H, Fu Y, Wang R, Ma Z, Qiu B, Li J, Hu D, Wang X, Shen J.
    Bioorg Med Chem; 2006 Jul 01; 14(13):4535-51. PubMed ID: 16510290
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