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Journal Abstract Search

302 related items for PubMed ID: 15585417

  • 1. Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer patients.
    Tong AW, Nemunaitis J, Su D, Zhang Y, Cunningham C, Senzer N, Netto G, Rich D, Mhashilkar A, Parker K, Coffee K, Ramesh R, Ekmekcioglu S, Grimm EA, van Wart Hood J, Merritt J, Chada S.
    Mol Ther; 2005 Jan; 11(1):160-72. PubMed ID: 15585417
    [Abstract] [Full Text] [Related]

  • 2. Clinical and local biological effects of an intratumoral injection of mda-7 (IL24; INGN 241) in patients with advanced carcinoma: a phase I study.
    Cunningham CC, Chada S, Merritt JA, Tong A, Senzer N, Zhang Y, Mhashilkar A, Parker K, Vukelja S, Richards D, Hood J, Coffee K, Nemunaitis J.
    Mol Ther; 2005 Jan; 11(1):149-59. PubMed ID: 15585416
    [Abstract] [Full Text] [Related]

  • 3. mda-7/IL24 kills pancreatic cancer cells by inhibition of the Wnt/PI3K signaling pathways: identification of IL-20 receptor-mediated bystander activity against pancreatic cancer.
    Chada S, Bocangel D, Ramesh R, Grimm EA, Mumm JB, Mhashilkar AM, Zheng M.
    Mol Ther; 2005 May; 11(5):724-33. PubMed ID: 15851011
    [Abstract] [Full Text] [Related]

  • 4. Melanoma differentiation-associated gene-7 (mda-7)/interleukin (IL)-24 induces anticancer immunity in a syngeneic murine model.
    Miyahara R, Banerjee S, Kawano K, Efferson C, Tsuda N, Miyahara Y, Ioannides CG, Chada S, Ramesh R.
    Cancer Gene Ther; 2006 Aug; 13(8):753-61. PubMed ID: 16543916
    [Abstract] [Full Text] [Related]

  • 5. Bystander activity of Ad-mda7: human MDA-7 protein kills melanoma cells via an IL-20 receptor-dependent but STAT3-independent mechanism.
    Chada S, Mhashilkar AM, Ramesh R, Mumm JB, Sutton RB, Bocangel D, Zheng M, Grimm EA, Ekmekcioglu S.
    Mol Ther; 2004 Dec; 10(6):1085-95. PubMed ID: 15564140
    [Abstract] [Full Text] [Related]

  • 6. Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy.
    Swisher SG, Roth JA, Komaki R, Gu J, Lee JJ, Hicks M, Ro JY, Hong WK, Merritt JA, Ahrar K, Atkinson NE, Correa AM, Dolormente M, Dreiling L, El-Naggar AK, Fossella F, Francisco R, Glisson B, Grammer S, Herbst R, Huaringa A, Kemp B, Khuri FR, Kurie JM, Liao Z, McDonnell TJ, Morice R, Morello F, Munden R, Papadimitrakopoulou V, Pisters KM, Putnam JB, Sarabia AJ, Shelton T, Stevens C, Shin DM, Smythe WR, Vaporciyan AA, Walsh GL, Yin M.
    Clin Cancer Res; 2003 Jan; 9(1):93-101. PubMed ID: 12538456
    [Abstract] [Full Text] [Related]

  • 7. Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR.
    Pataer A, Vorburger SA, Chada S, Balachandran S, Barber GN, Roth JA, Hunt KK, Swisher SG.
    Mol Ther; 2005 May; 11(5):717-23. PubMed ID: 15851010
    [Abstract] [Full Text] [Related]

  • 8. Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated -7 (mda-7)/interleukin-24 (IL-24) gene.
    Saito Y, Miyahara R, Gopalan B, Litvak A, Inoue S, Shanker M, Branch CD, Mhashilkar AM, Roth JA, Chada S, Ramesh R.
    Cancer Gene Ther; 2005 Mar; 12(3):238-47. PubMed ID: 15578066
    [Abstract] [Full Text] [Related]

  • 9. Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties.
    Huang EY, Madireddi MT, Gopalkrishnan RV, Leszczyniecka M, Su Z, Lebedeva IV, Kang D, Jiang H, Lin JJ, Alexandre D, Chen Y, Vozhilla N, Mei MX, Christiansen KA, Sivo F, Goldstein NI, Mhashilkar AB, Chada S, Huberman E, Pestka S, Fisher PB.
    Oncogene; 2001 Oct 25; 20(48):7051-63. PubMed ID: 11704829
    [Abstract] [Full Text] [Related]

  • 10. mda-7 (IL-24): signaling and functional roles.
    Sarkar D, Su ZZ, Lebedeva IV, Sauane M, Gopalkrishnan RV, Dent P, Fisher PB.
    Biotechniques; 2002 Oct 25; Suppl():30-9. PubMed ID: 12395925
    [Abstract] [Full Text] [Related]

  • 11. Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial.
    Stewart AK, Lassam NJ, Quirt IC, Bailey DJ, Rotstein LE, Krajden M, Dessureault S, Gallinger S, Cappe D, Wan Y, Addison CL, Moen RC, Gauldie J, Graham FL.
    Gene Ther; 1999 Mar 25; 6(3):350-63. PubMed ID: 10435085
    [Abstract] [Full Text] [Related]

  • 12. Activation of the Fas-FasL signaling pathway by MDA-7/IL-24 kills human ovarian cancer cells.
    Gopalan B, Litvak A, Sharma S, Mhashilkar AM, Chada S, Ramesh R.
    Cancer Res; 2005 Apr 15; 65(8):3017-24. PubMed ID: 15833826
    [Abstract] [Full Text] [Related]

  • 13. MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family.
    Chada S, Sutton RB, Ekmekcioglu S, Ellerhorst J, Mumm JB, Leitner WW, Yang HY, Sahin AA, Hunt KK, Fuson KL, Poìndexter N, Roth JA, Ramesh R, Grimm EA, Mhashilkar AM.
    Int Immunopharmacol; 2004 May 15; 4(5):649-67. PubMed ID: 15120650
    [Abstract] [Full Text] [Related]

  • 14. Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo.
    Saeki T, Mhashilkar A, Swanson X, Zou-Yang XH, Sieger K, Kawabe S, Branch CD, Zumstein L, Meyn RE, Roth JA, Chada S, Ramesh R.
    Oncogene; 2002 Jul 04; 21(29):4558-66. PubMed ID: 12085234
    [Abstract] [Full Text] [Related]

  • 15. The cancer growth suppressing gene mda-7 induces apoptosis selectively in human melanoma cells.
    Lebedeva IV, Su ZZ, Chang Y, Kitada S, Reed JC, Fisher PB.
    Oncogene; 2002 Jan 24; 21(5):708-18. PubMed ID: 11850799
    [Abstract] [Full Text] [Related]

  • 16. Unique aspects of mda-7/IL-24 antitumor bystander activity: establishing a role for secretion of MDA-7/IL-24 protein by normal cells.
    Su Z, Emdad L, Sauane M, Lebedeva IV, Sarkar D, Gupta P, James CD, Randolph A, Valerie K, Walter MR, Dent P, Fisher PB.
    Oncogene; 2005 Nov 17; 24(51):7552-66. PubMed ID: 16044151
    [Abstract] [Full Text] [Related]

  • 17. Biological activity and safety of adenoviral vector-expressed wild-type p53 after intratumoral injection in melanoma and breast cancer patients with p53-overexpressing tumors.
    Dummer R, Bergh J, Karlsson Y, Horowitz JA, Mulder NH, Huinink DTB, Burg G, Hofbauer G, Osanto S.
    Cancer Gene Ther; 2000 Jul 17; 7(7):1069-76. PubMed ID: 10917210
    [Abstract] [Full Text] [Related]

  • 18. High-level, beta-catenin/TCF-dependent transgene expression in secondary colorectal cancer tissue.
    Lipinski KS, Djeha AH, Ismail T, Mountain A, Young LS, Wrighton CJ.
    Mol Ther; 2001 Oct 17; 4(4):365-71. PubMed ID: 11592840
    [Abstract] [Full Text] [Related]

  • 19. mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).
    Lebedeva IV, Emdad L, Su ZZ, Gupta P, Sauane M, Sarkar D, Staudt MR, Liu SJ, Taher MM, Xiao R, Barral P, Lee SG, Wang D, Vozhilla N, Park ES, Chatman L, Boukerche H, Ramesh R, Inoue S, Chada S, Li R, De Pass AL, Mahasreshti PJ, Dmitriev IP, Curiel DT, Yacoub A, Grant S, Dent P, Senzer N, Nemunaitis JJ, Fisher PB.
    Int J Oncol; 2007 Nov 17; 31(5):985-1007. PubMed ID: 17912425
    [Abstract] [Full Text] [Related]

  • 20. Biological activities of a recombinant adenovirus p53 (SCH 58500) administered by hepatic arterial infusion in a Phase 1 colorectal cancer trial.
    Atencio IA, Grace M, Bordens R, Fritz M, Horowitz JA, Hutchins B, Indelicato S, Jacobs S, Kolz K, Maneval D, Musco ML, Shinoda J, Venook A, Wen S, Warren R.
    Cancer Gene Ther; 2006 Feb 17; 13(2):169-81. PubMed ID: 16082381
    [Abstract] [Full Text] [Related]

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