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1637 related items for PubMed ID: 15593186

  • 1. Selective inhibition of activin receptor-like kinase 5 signaling blocks profibrotic transforming growth factor beta responses in skin fibroblasts.
    Mori Y, Ishida W, Bhattacharyya S, Li Y, Platanias LC, Varga J.
    Arthritis Rheum; 2004 Dec; 50(12):4008-21. PubMed ID: 15593186
    [Abstract] [Full Text] [Related]

  • 2. Disruption of transforming growth factor beta signaling and profibrotic responses in normal skin fibroblasts by peroxisome proliferator-activated receptor gamma.
    Ghosh AK, Bhattacharyya S, Lakos G, Chen SJ, Mori Y, Varga J.
    Arthritis Rheum; 2004 Apr; 50(4):1305-18. PubMed ID: 15077315
    [Abstract] [Full Text] [Related]

  • 3. Fibroblast expression of the coactivator p300 governs the intensity of profibrotic response to transforming growth factor beta.
    Bhattacharyya S, Ghosh AK, Pannu J, Mori Y, Takagawa S, Chen G, Trojanowska M, Gilliam AC, Varga J.
    Arthritis Rheum; 2005 Apr; 52(4):1248-58. PubMed ID: 15818659
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  • 4. Expression and regulation of intracellular SMAD signaling in scleroderma skin fibroblasts.
    Mori Y, Chen SJ, Varga J.
    Arthritis Rheum; 2003 Jul; 48(7):1964-78. PubMed ID: 12847691
    [Abstract] [Full Text] [Related]

  • 5. SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7.
    DaCosta Byfield S, Major C, Laping NJ, Roberts AB.
    Mol Pharmacol; 2004 Mar; 65(3):744-52. PubMed ID: 14978253
    [Abstract] [Full Text] [Related]

  • 6. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
    Subramanian G, Schwarz RE, Higgins L, McEnroe G, Chakravarty S, Dugar S, Reiss M.
    Cancer Res; 2004 Aug 01; 64(15):5200-11. PubMed ID: 15289325
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  • 7. Rapamycin induces the TGFbeta1/Smad signaling cascade in renal mesangial cells upstream of mTOR.
    Osman B, Doller A, Akool el-S, Holdener M, Hintermann E, Pfeilschifter J, Eberhardt W.
    Cell Signal; 2009 Dec 01; 21(12):1806-17. PubMed ID: 19666112
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  • 8. Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma.
    Pannu J, Gardner H, Shearstone JR, Smith E, Trojanowska M.
    Arthritis Rheum; 2006 Sep 01; 54(9):3011-21. PubMed ID: 16947635
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  • 11. A novel inhibitor of Smad-dependent transcriptional activation suppresses tissue fibrosis in mouse models of systemic sclerosis.
    Hasegawa M, Matsushita Y, Horikawa M, Higashi K, Tomigahara Y, Kaneko H, Shirasaki F, Fujimoto M, Takehara K, Sato S.
    Arthritis Rheum; 2009 Nov 01; 60(11):3465-75. PubMed ID: 19877032
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  • 14. Blockade of endogenous transforming growth factor beta signaling prevents up-regulated collagen synthesis in scleroderma fibroblasts: association with increased expression of transforming growth factor beta receptors.
    Ihn H, Yamane K, Kubo M, Tamaki K.
    Arthritis Rheum; 2001 Feb 01; 44(2):474-80. PubMed ID: 11229480
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  • 15. Selective inhibitors of type I receptor kinase block cellular transforming growth factor-beta signaling.
    Ge R, Rajeev V, Subramanian G, Reiss KA, Liu D, Higgins L, Joly A, Dugar S, Chakravarty J, Henson M, McEnroe G, Schreiner G, Reiss M.
    Biochem Pharmacol; 2004 Jul 01; 68(1):41-50. PubMed ID: 15183116
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  • 16. Contribution of activin receptor-like kinase 5 (transforming growth factor beta receptor type I) signaling to the fibrotic phenotype of scleroderma fibroblasts.
    Chen Y, Shi-wen X, Eastwood M, Black CM, Denton CP, Leask A, Abraham DJ.
    Arthritis Rheum; 2006 Apr 01; 54(4):1309-16. PubMed ID: 16575856
    [Abstract] [Full Text] [Related]

  • 17. Autocrine TGFbeta signaling mediates vitamin D3 analog-induced growth inhibition in breast cells.
    Yang L, Yang J, Venkateswarlu S, Ko T, Brattain MG.
    J Cell Physiol; 2001 Sep 01; 188(3):383-93. PubMed ID: 11473365
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  • 18. Angiotensin II activates connective tissue growth factor and induces extracellular matrix changes involving Smad/activation and p38 mitogen-activated protein kinase signalling pathways in human dermal fibroblasts.
    Zhang GY, Li X, Yi CG, Pan H, He GD, Yu Q, Jiang LF, Xu WH, Li ZJ, Ding J, Lin DS, Gao WY.
    Exp Dermatol; 2009 Nov 01; 18(11):947-53. PubMed ID: 19397700
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  • 19. Contractility as a prerequisite for TGF-beta-induced myofibroblast transdifferentiation in human tenon fibroblasts.
    Meyer-ter-Vehn T, Sieprath S, Katzenberger B, Gebhardt S, Grehn F, Schlunck G.
    Invest Ophthalmol Vis Sci; 2006 Nov 01; 47(11):4895-904. PubMed ID: 17065504
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  • 20. A novel mechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition.
    Yang J, Dai C, Liu Y.
    J Am Soc Nephrol; 2005 Jan 01; 16(1):68-78. PubMed ID: 15537870
    [Abstract] [Full Text] [Related]

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