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685 related items for PubMed ID: 15593193

  • 1. Regulation of the expression of 5-lipoxygenase-activating protein/5-lipoxygenase and the synthesis of leukotriene B(4) in osteoarthritic chondrocytes: role of transforming growth factor beta and eicosanoids.
    Martel-Pelletier J, Mineau F, Fahmi H, Laufer S, Reboul P, Boileau C, Lavigne M, Pelletier JP.
    Arthritis Rheum; 2004 Dec; 50(12):3925-33. PubMed ID: 15593193
    [Abstract] [Full Text] [Related]

  • 2. The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein.
    Maxis K, Delalandre A, Martel-Pelletier J, Pelletier JP, Duval N, Lajeunesse D.
    Arthritis Res Ther; 2006 Dec; 8(6):R181. PubMed ID: 17156456
    [Abstract] [Full Text] [Related]

  • 3. The regulation of human MMP-13 by licofelone, an inhibitor of cyclo-oxygenases and 5-lipoxygenase, in human osteoarthritic chondrocytes is mediated by the inhibition of the p38 MAP kinase signalling pathway.
    Boileau C, Pelletier JP, Tardif G, Fahmi H, Laufer S, Lavigne M, Martel-Pelletier J.
    Ann Rheum Dis; 2005 Jun; 64(6):891-8. PubMed ID: 15498796
    [Abstract] [Full Text] [Related]

  • 4. Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition.
    Paredes Y, Massicotte F, Pelletier JP, Martel-Pelletier J, Laufer S, Lajeunesse D.
    Arthritis Rheum; 2002 Jul; 46(7):1804-12. PubMed ID: 12124864
    [Abstract] [Full Text] [Related]

  • 5. Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.
    Marcouiller P, Pelletier JP, Guévremont M, Martel-Pelletier J, Ranger P, Laufer S, Reboul P.
    J Rheumatol; 2005 Apr; 32(4):704-12. PubMed ID: 15801029
    [Abstract] [Full Text] [Related]

  • 6. Activation of diverse eicosanoid pathways in osteoarthritic cartilage: a lipidomic and genomic analysis.
    Attur M, Dave M, Abramson SB, Amin A.
    Bull NYU Hosp Jt Dis; 2012 Apr; 70(2):99-108. PubMed ID: 22891999
    [Abstract] [Full Text] [Related]

  • 7. Differential patterns of response to doxycycline and transforming growth factor beta1 in the down-regulation of collagenases in osteoarthritic and normal human chondrocytes.
    Shlopov BV, Smith GN, Cole AA, Hasty KA.
    Arthritis Rheum; 1999 Apr; 42(4):719-27. PubMed ID: 10211886
    [Abstract] [Full Text] [Related]

  • 8. Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes.
    Chen SH, Fahmi H, Shi Q, Benderdour M.
    Arthritis Res Ther; 2010 Apr; 12(1):R21. PubMed ID: 20144213
    [Abstract] [Full Text] [Related]

  • 9. Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin.
    Fiorucci S, Distrutti E, Mencarelli A, Morelli A, Laufor SA, Cirino G, Wallace JL.
    Br J Pharmacol; 2003 Aug; 139(7):1351-9. PubMed ID: 12890715
    [Abstract] [Full Text] [Related]

  • 10. Collagenase 3 production by human osteoarthritic chondrocytes in response to growth factors and cytokines is a function of the physiologic state of the cells.
    Tardif G, Pelletier JP, Dupuis M, Geng C, Cloutier JM, Martel-Pelletier J.
    Arthritis Rheum; 1999 Jun; 42(6):1147-58. PubMed ID: 10366107
    [Abstract] [Full Text] [Related]

  • 11. The catabolic pathway mediated by Toll-like receptors in human osteoarthritic chondrocytes.
    Kim HA, Cho ML, Choi HY, Yoon CS, Jhun JY, Oh HJ, Kim HY.
    Arthritis Rheum; 2006 Jul; 54(7):2152-63. PubMed ID: 16802353
    [Abstract] [Full Text] [Related]

  • 12. Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts.
    Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J.
    Arthritis Rheum; 2004 Aug; 50(8):2521-30. PubMed ID: 15334466
    [Abstract] [Full Text] [Related]

  • 13. Mediation of interleukin-1beta-induced transforming growth factor beta1 expression by activator protein 4 transcription factor in primary cultures of bovine articular chondrocytes: possible cooperation with activator protein 1.
    Andriamanalijaona R, Felisaz N, Kim SJ, King-Jones K, Lehmann M, Pujol JP, Boumediene K.
    Arthritis Rheum; 2003 Jun; 48(6):1569-81. PubMed ID: 12794825
    [Abstract] [Full Text] [Related]

  • 14. Differential regulation of cyclo-oxygenase-2 and 5-lipoxygenase-activating protein (FLAP) expression by glucocorticoids in monocytic cells.
    Goppelt-Struebe M, Schaefer D, Habenicht AJ.
    Br J Pharmacol; 1997 Oct; 122(4):619-24. PubMed ID: 9375956
    [Abstract] [Full Text] [Related]

  • 15. Cyclooxygenase- and lipoxygenase-derived eicosanoids in bronchoalveolar lavage fluid from patients with scleroderma lung disease: an imbalance between proinflammatory and antiinflammatory lipid mediators.
    Kowal-Bielecka O, Kowal K, Distler O, Rojewska J, Bodzenta-Lukaszyk A, Michel BA, Gay RE, Gay S, Sierakowski S.
    Arthritis Rheum; 2005 Dec; 52(12):3783-91. PubMed ID: 16320329
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of CD95 apoptotic signaling by interferon-gamma in human osteoarthritic chondrocytes is associated with increased expression of FLICE inhibitory protein.
    Grassi F, Piacentini A, Cristino S, Toneguzzi S, Facchini A, Lisignoli G.
    Arthritis Rheum; 2004 Feb; 50(2):498-506. PubMed ID: 14872492
    [Abstract] [Full Text] [Related]

  • 17. Aceclofenac increases the synthesis of interleukin 1 receptor antagonist and decreases the production of nitric oxide in human articular chondrocytes.
    Maneiro E, López-Armada MJ, Fernández-Sueiro JL, Lema B, Galdo F, Blanco FJ.
    J Rheumatol; 2001 Dec; 28(12):2692-9. PubMed ID: 11764219
    [Abstract] [Full Text] [Related]

  • 18. Avocado/soybean unsaponifiables prevent the inhibitory effect of osteoarthritic subchondral osteoblasts on aggrecan and type II collagen synthesis by chondrocytes.
    Henrotin YE, Deberg MA, Crielaard JM, Piccardi N, Msika P, Sanchez C.
    J Rheumatol; 2006 Aug; 33(8):1668-78. PubMed ID: 16832844
    [Abstract] [Full Text] [Related]

  • 19. Lipoxygenase metabolism following laser induced retinal injury in rabbits.
    Naveh N, Weissman C, Marshall J.
    Curr Eye Res; 2000 Jul; 21(1):554-9. PubMed ID: 11035536
    [Abstract] [Full Text] [Related]

  • 20. Licofelone (ML-3000), a dual inhibitor of 5-lipoxygenase and cyclooxygenase, reduces the level of cartilage chondrocyte death in vivo in experimental dog osteoarthritis: inhibition of pro-apoptotic factors.
    Boileau C, Martel-Pelletier J, Jouzeau JY, Netter P, Moldovan F, Laufer S, Tries S, Pelletier JP.
    J Rheumatol; 2002 Jul; 29(7):1446-53. PubMed ID: 12136904
    [Abstract] [Full Text] [Related]

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