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496 related items for PubMed ID: 15596714

  • 1. Apoptotic and autophagic cell death induced by histone deacetylase inhibitors.
    Shao Y, Gao Z, Marks PA, Jiang X.
    Proc Natl Acad Sci U S A; 2004 Dec 28; 101(52):18030-5. PubMed ID: 15596714
    [Abstract] [Full Text] [Related]

  • 2. The novel histone deacetylase inhibitor, N-hydroxy-7-(2-naphthylthio) hepatonomide, exhibits potent antitumor activity due to cytochrome-c-release-mediated apoptosis in renal cell carcinoma cells.
    Park KC, Heo JH, Jeon JY, Choi HJ, Jo AR, Kim SW, Kwon HJ, Hong SJ, Han KS.
    BMC Cancer; 2015 Jan 23; 15():19. PubMed ID: 25613585
    [Abstract] [Full Text] [Related]

  • 3. Histone deacetylase activity regulates apaf-1 and caspase 3 expression in the developing mouse retina.
    Wallace DM, Donovan M, Cotter TG.
    Invest Ophthalmol Vis Sci; 2006 Jul 23; 47(7):2765-72. PubMed ID: 16799012
    [Abstract] [Full Text] [Related]

  • 4. The histone deacetylase inhibitor suberic bishydroxamate regulates the expression of multiple apoptotic mediators and induces mitochondria-dependent apoptosis of melanoma cells.
    Zhang XD, Gillespie SK, Borrow JM, Hersey P.
    Mol Cancer Ther; 2004 Apr 23; 3(4):425-35. PubMed ID: 15078986
    [Abstract] [Full Text] [Related]

  • 5. The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen species.
    Ruefli AA, Ausserlechner MJ, Bernhard D, Sutton VR, Tainton KM, Kofler R, Smyth MJ, Johnstone RW.
    Proc Natl Acad Sci U S A; 2001 Sep 11; 98(19):10833-8. PubMed ID: 11535817
    [Abstract] [Full Text] [Related]

  • 6. Interactive effects of histone deacetylase inhibitors and TRAIL on apoptosis in human leukemia cells: involvement of both death receptor and mitochondrial pathways.
    Shankar S, Singh TR, Fandy TE, Luetrakul T, Ross DD, Srivastava RK.
    Int J Mol Med; 2005 Dec 11; 16(6):1125-38. PubMed ID: 16273296
    [Abstract] [Full Text] [Related]

  • 7. Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway.
    Medina V, Edmonds B, Young GP, James R, Appleton S, Zalewski PD.
    Cancer Res; 1997 Sep 01; 57(17):3697-707. PubMed ID: 9288776
    [Abstract] [Full Text] [Related]

  • 8. Induction of apoptosis by apicidin, a histone deacetylase inhibitor, via the activation of mitochondria-dependent caspase cascades in human Bcr-Abl-positive leukemia cells.
    Cheong JW, Chong SY, Kim JY, Eom JI, Jeung HK, Maeng HY, Lee ST, Min YH.
    Clin Cancer Res; 2003 Oct 15; 9(13):5018-27. PubMed ID: 14581377
    [Abstract] [Full Text] [Related]

  • 9. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors.
    Pei XY, Dai Y, Grant S.
    Clin Cancer Res; 2004 Jun 01; 10(11):3839-52. PubMed ID: 15173093
    [Abstract] [Full Text] [Related]

  • 10. Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA).
    Henderson C, Mizzau M, Paroni G, Maestro R, Schneider C, Brancolini C.
    J Biol Chem; 2003 Apr 04; 278(14):12579-89. PubMed ID: 12556448
    [Abstract] [Full Text] [Related]

  • 11. Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.
    Burek M, Maddika S, Burek CJ, Daniel PT, Schulze-Osthoff K, Los M.
    Oncogene; 2006 Apr 06; 25(15):2213-22. PubMed ID: 16288204
    [Abstract] [Full Text] [Related]

  • 12. Induction of apoptosis by trichostatin A, a histone deacetylase inhibitor, is associated with inhibition of cyclooxygenase-2 activity in human non-small cell lung cancer cells.
    Choi YH.
    Int J Oncol; 2005 Aug 06; 27(2):473-9. PubMed ID: 16010430
    [Abstract] [Full Text] [Related]

  • 13. Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors.
    Terui T, Murakami K, Takimoto R, Takahashi M, Takada K, Murakami T, Minami S, Matsunaga T, Takayama T, Kato J, Niitsu Y.
    Cancer Res; 2003 Dec 15; 63(24):8948-54. PubMed ID: 14695212
    [Abstract] [Full Text] [Related]

  • 14. Suppression of caspase-11 expression by histone deacetylase inhibitors.
    Heo H, Yoo L, Shin KS, Kang SJ.
    Biochem Biophys Res Commun; 2009 Jan 02; 378(1):79-83. PubMed ID: 19013432
    [Abstract] [Full Text] [Related]

  • 15. Concomitant epigenetic targeting of LSD1 and HDAC synergistically induces mitochondrial apoptosis in rhabdomyosarcoma cells.
    Haydn T, Metzger E, Schuele R, Fulda S.
    Cell Death Dis; 2017 Jun 15; 8(6):e2879. PubMed ID: 28617441
    [Abstract] [Full Text] [Related]

  • 16. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
    Rahmani M, Reese E, Dai Y, Bauer C, Payne SG, Dent P, Spiegel S, Grant S.
    Cancer Res; 2005 Mar 15; 65(6):2422-32. PubMed ID: 15781658
    [Abstract] [Full Text] [Related]

  • 17. The histone deacetylase inhibitor FR901228 induces caspase-dependent apoptosis via the mitochondrial pathway in small cell lung cancer cells.
    Doi S, Soda H, Oka M, Tsurutani J, Kitazaki T, Nakamura Y, Fukuda M, Yamada Y, Kamihira S, Kohno S.
    Mol Cancer Ther; 2004 Nov 15; 3(11):1397-402. PubMed ID: 15542778
    [Abstract] [Full Text] [Related]

  • 18. Histone deacetylase inhibitors reduce VEGF production and induce growth suppression and apoptosis in human mantle cell lymphoma.
    Heider U, Kaiser M, Sterz J, Zavrski I, Jakob C, Fleissner C, Eucker J, Possinger K, Sezer O.
    Eur J Haematol; 2006 Jan 15; 76(1):42-50. PubMed ID: 16343270
    [Abstract] [Full Text] [Related]

  • 19. The histone-deacetylase inhibitor SAHA potentiates proapoptotic effects of 5-fluorouracil and irinotecan in hepatoma cells.
    Ocker M, Alajati A, Ganslmayer M, Zopf S, Lüders M, Neureiter D, Hahn EG, Schuppan D, Herold C.
    J Cancer Res Clin Oncol; 2005 Jun 15; 131(6):385-94. PubMed ID: 15754201
    [Abstract] [Full Text] [Related]

  • 20. Synergistic induction of mitochondrial damage and apoptosis in human leukemia cells by flavopiridol and the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA).
    Almenara J, Rosato R, Grant S.
    Leukemia; 2002 Jul 15; 16(7):1331-43. PubMed ID: 12094258
    [Abstract] [Full Text] [Related]

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