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245 related items for PubMed ID: 15601622

  • 1. The overexpression of presenilin2 and Alzheimer's-disease-linked presenilin2 variants influences TRPC6-enhanced Ca2+ entry into HEK293 cells.
    Lessard CB, Lussier MP, Cayouette S, Bourque G, Boulay G.
    Cell Signal; 2005 Apr; 17(4):437-45. PubMed ID: 15601622
    [Abstract] [Full Text] [Related]

  • 2. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
    Zatti G, Burgo A, Giacomello M, Barbiero L, Ghidoni R, Sinigaglia G, Florean C, Bagnoli S, Binetti G, Sorbi S, Pizzo P, Fasolato C.
    Cell Calcium; 2006 Jun; 39(6):539-50. PubMed ID: 16620965
    [Abstract] [Full Text] [Related]

  • 3. Receptor-operated Ca2+ entry mediated by TRPC3/TRPC6 proteins in rat prostate smooth muscle (PS1) cell line.
    Thebault S, Zholos A, Enfissi A, Slomianny C, Dewailly E, Roudbaraki M, Parys J, Prevarskaya N.
    J Cell Physiol; 2005 Jul; 204(1):320-8. PubMed ID: 15672411
    [Abstract] [Full Text] [Related]

  • 4. The canonical transient receptor potential 6 channel as a putative phosphatidylinositol 3,4,5-trisphosphate-sensitive calcium entry system.
    Tseng PH, Lin HP, Hu H, Wang C, Zhu MX, Chen CS.
    Biochemistry; 2004 Sep 21; 43(37):11701-8. PubMed ID: 15362854
    [Abstract] [Full Text] [Related]

  • 5. Alzheimer's disease-linked mutation of presenilin 2 (N141I-PS2) drastically lowers APPalpha secretion: control by the proteasome.
    Marambaud P, Alves da Costa C, Ancolio K, Checler F.
    Biochem Biophys Res Commun; 1998 Nov 09; 252(1):134-8. PubMed ID: 9813158
    [Abstract] [Full Text] [Related]

  • 6. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
    Wiley JC, Hudson M, Kanning KC, Schecterson LC, Bothwell M.
    J Neurochem; 2005 Sep 09; 94(5):1189-201. PubMed ID: 15992373
    [Abstract] [Full Text] [Related]

  • 7. Neurons overexpressing mutant presenilin-1 are more sensitive to apoptosis induced by endoplasmic reticulum-Golgi stress.
    Terro F, Czech C, Esclaire F, Elyaman W, Yardin C, Baclet MC, Touchet N, Tremp G, Pradier L, Hugon J.
    J Neurosci Res; 2002 Aug 15; 69(4):530-9. PubMed ID: 12210846
    [Abstract] [Full Text] [Related]

  • 8. Presenilin 2 familial Alzheimer's disease mutations result in partial loss of function and dramatic changes in Abeta 42/40 ratios.
    Walker ES, Martinez M, Brunkan AL, Goate A.
    J Neurochem; 2005 Jan 15; 92(2):294-301. PubMed ID: 15663477
    [Abstract] [Full Text] [Related]

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  • 10. Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.
    Bentahir M, Nyabi O, Verhamme J, Tolia A, Horré K, Wiltfang J, Esselmann H, De Strooper B.
    J Neurochem; 2006 Feb 15; 96(3):732-42. PubMed ID: 16405513
    [Abstract] [Full Text] [Related]

  • 11. Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression.
    Sato N, Urano F, Yoon Leem J, Kim SH, Li M, Donoviel D, Bernstein A, Lee AS, Ron D, Veselits ML, Sisodia SS, Thinakaran G.
    Nat Cell Biol; 2000 Dec 15; 2(12):863-70. PubMed ID: 11146649
    [Abstract] [Full Text] [Related]

  • 12. [Molecular basics of Alzheimer's disease].
    Grigorenko AP, Rogaev EI.
    Mol Biol (Mosk); 2007 Dec 15; 41(2):331-45. PubMed ID: 17514900
    [Abstract] [Full Text] [Related]

  • 13. Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells.
    Ramalho RM, Borralho PM, Castro RE, Solá S, Steer CJ, Rodrigues CM.
    J Neurochem; 2006 Sep 15; 98(5):1610-8. PubMed ID: 16923170
    [Abstract] [Full Text] [Related]

  • 14. Mechanism of inhibition of TRPC cation channels by 2-aminoethoxydiphenylborane.
    Lievremont JP, Bird GS, Putney JW.
    Mol Pharmacol; 2005 Sep 15; 68(3):758-62. PubMed ID: 15933213
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  • 16. Multiple regulation by calcium of murine homologues of transient receptor potential proteins TRPC6 and TRPC7 expressed in HEK293 cells.
    Shi J, Mori E, Mori Y, Mori M, Li J, Ito Y, Inoue R.
    J Physiol; 2004 Dec 01; 561(Pt 2):415-32. PubMed ID: 15579537
    [Abstract] [Full Text] [Related]

  • 17. Presenilins upregulate functional K+ channel currents in mammalian cells.
    Malin SA, Guo WX, Jafari G, Goate AM, Nerbonne JM.
    Neurobiol Dis; 1998 Apr 01; 4(6):398-409. PubMed ID: 9666479
    [Abstract] [Full Text] [Related]

  • 18. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
    Majercak J, Ray WJ, Espeseth A, Simon A, Shi XP, Wolffe C, Getty K, Marine S, Stec E, Ferrer M, Strulovici B, Bartz S, Gates A, Xu M, Huang Q, Ma L, Shughrue P, Burchard J, Colussi D, Pietrak B, Kahana J, Beher D, Rosahl T, Shearman M, Hazuda D, Sachs AB, Koblan KS, Seabrook GR, Stone DJ.
    Proc Natl Acad Sci U S A; 2006 Nov 21; 103(47):17967-72. PubMed ID: 17098871
    [Abstract] [Full Text] [Related]

  • 19. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
    Shirotani K, Tomioka M, Kremmer E, Haass C, Steiner H.
    Neurobiol Dis; 2007 Jul 21; 27(1):102-7. PubMed ID: 17560791
    [Abstract] [Full Text] [Related]

  • 20. Protease digestion indicates that endogenous presenilin 1 is present in at least two physical forms.
    Oh YS, Turner RJ.
    Biochem Biophys Res Commun; 2006 Jul 21; 346(1):330-4. PubMed ID: 16756946
    [Abstract] [Full Text] [Related]

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