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Journal Abstract Search

369 related items for PubMed ID: 15607965

  • 1. Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity.
    O'Shea CC, Johnson L, Bagus B, Choi S, Nicholas C, Shen A, Boyle L, Pandey K, Soria C, Kunich J, Shen Y, Habets G, Ginzinger D, McCormick F.
    Cancer Cell; 2004 Dec; 6(6):611-23. PubMed ID: 15607965
    [Abstract] [Full Text] [Related]

  • 2. Heat shock phenocopies E1B-55K late functions and selectively sensitizes refractory tumor cells to ONYX-015 oncolytic viral therapy.
    O'Shea CC, Soria C, Bagus B, McCormick F.
    Cancer Cell; 2005 Jul; 8(1):61-74. PubMed ID: 16023599
    [Abstract] [Full Text] [Related]

  • 3. Analyses of single-amino-acid substitution mutants of adenovirus type 5 E1B-55K protein.
    Shen Y, Kitzes G, Nye JA, Fattaey A, Hermiston T.
    J Virol; 2001 May; 75(9):4297-307. PubMed ID: 11287579
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  • 4. p53-Independent and -dependent requirements for E1B-55K in adenovirus type 5 replication.
    Harada JN, Berk AJ.
    J Virol; 1999 Jul; 73(7):5333-44. PubMed ID: 10364280
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of p53 by adenovirus type 12 E1B-55K deregulates cell cycle control and sensitizes tumor cells to genotoxic agents.
    Li Q, Zhao LY, Zheng Z, Yang H, Santiago A, Liao D.
    J Virol; 2011 Aug; 85(16):7976-88. PubMed ID: 21680522
    [Abstract] [Full Text] [Related]

  • 6. A novel apoptotic mechanism of genetically engineered adenovirus-mediated tumour-specific p53 overexpression through E1A-dependent p21 and MDM2 suppression.
    Yamasaki Y, Tazawa H, Hashimoto Y, Kojima T, Kuroda S, Yano S, Yoshida R, Uno F, Mizuguchi H, Ohtsuru A, Urata Y, Kagawa S, Fujiwara T.
    Eur J Cancer; 2012 Sep; 48(14):2282-91. PubMed ID: 22244827
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  • 7. Modification of the p53 transgene of a replication-competent adenovirus prevents mdm2- and E1b-55kD-mediated degradation of p53.
    Sauthoff H, Pipiya T, Chen S, Heitner S, Cheng J, Huang YQ, Rom WN, Hay JG.
    Cancer Gene Ther; 2006 Jul; 13(7):686-95. PubMed ID: 16470212
    [Abstract] [Full Text] [Related]

  • 8. Downregulation of Mdm2 and Mdm4 enhances viral gene expression during adenovirus infection.
    Yang H, Zheng Z, Zhao LY, Li Q, Liao D.
    Cell Cycle; 2012 Feb 01; 11(3):582-93. PubMed ID: 22262167
    [Abstract] [Full Text] [Related]

  • 9. Infection with E1B-mutant adenovirus stabilizes p53 but blocks p53 acetylation and activity through E1A.
    Savelyeva I, Dobbelstein M.
    Oncogene; 2011 Feb 17; 30(7):865-75. PubMed ID: 20935676
    [Abstract] [Full Text] [Related]

  • 10. Replication of an E1B 55-kilodalton protein-deficient adenovirus (ONYX-015) is restored by gain-of-function rather than loss-of-function p53 mutants.
    Hann B, Balmain A.
    J Virol; 2003 Nov 17; 77(21):11588-95. PubMed ID: 14557644
    [Abstract] [Full Text] [Related]

  • 11. Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015).
    Ries SJ, Brandts CH, Chung AS, Biederer CH, Hann BC, Lipner EM, McCormick F, Korn WM.
    Nat Med; 2000 Oct 17; 6(10):1128-33. PubMed ID: 11017144
    [Abstract] [Full Text] [Related]

  • 12. Bcl-2 and adenovirus E1B 19 kDA protein prevent E1A-induced processing of CPP32 and cleavage of poly(ADP-ribose) polymerase.
    Boulakia CA, Chen G, Ng FW, Teodoro JG, Branton PE, Nicholson DW, Poirier GG, Shore GC.
    Oncogene; 1996 Feb 01; 12(3):529-35. PubMed ID: 8637709
    [Abstract] [Full Text] [Related]

  • 13. Functional complementation of the adenovirus E1B 19-kilodalton protein with Bcl-2 in the inhibition of apoptosis in infected cells.
    Chiou SK, Tseng CC, Rao L, White E.
    J Virol; 1994 Oct 01; 68(10):6553-66. PubMed ID: 8083992
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  • 16. Interactions between adenovirus proteins and the p53 pathway: the development of ONYX-015.
    McCormick F.
    Semin Cancer Biol; 2000 Dec 01; 10(6):453-9. PubMed ID: 11170867
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  • 19. Adenovirus E1B 55-kilodalton protein is a p53-SUMO1 E3 ligase that represses p53 and stimulates its nuclear export through interactions with promyelocytic leukemia nuclear bodies.
    Pennella MA, Liu Y, Woo JL, Kim CA, Berk AJ.
    J Virol; 2010 Dec 01; 84(23):12210-25. PubMed ID: 20861261
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