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Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

302 related items for PubMed ID: 15608076

  • 1. The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5.
    Lin HL, Kent UM, Hollenberg PF.
    J Pharmacol Exp Ther; 2005 Apr; 313(1):154-64. PubMed ID: 15608076
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  • 2. Mechanism-based inactivation of cytochromes P450 2B1 and P450 2B6 by 2-phenyl-2-(1-piperidinyl)propane.
    Chun J, Kent UM, Moss RM, Sayre LM, Hollenberg PF.
    Drug Metab Dispos; 2000 Aug; 28(8):905-11. PubMed ID: 10901699
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  • 3. Metabolism of bergamottin by cytochromes P450 2B6 and 3A5.
    Kent UM, Lin HL, Noon KR, Harris DL, Hollenberg PF.
    J Pharmacol Exp Ther; 2006 Sep; 318(3):992-1005. PubMed ID: 16785317
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  • 4. Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice.
    He K, Iyer KR, Hayes RN, Sinz MW, Woolf TF, Hollenberg PF.
    Chem Res Toxicol; 1998 Apr; 11(4):252-9. PubMed ID: 9548795
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  • 5. Metabolic activation of mifepristone [RU486; 17beta-hydroxy-11beta-(4-dimethylaminophenyl)-17alpha-(1-propynyl)-estra-4,9-dien-3-one] by mammalian cytochromes P450 and the mechanism-based inactivation of human CYP2B6.
    Lin HL, Zhang H, Hollenberg PF.
    J Pharmacol Exp Ther; 2009 Apr; 329(1):26-37. PubMed ID: 19168709
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  • 9. Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites.
    Kent UM, Mills DE, Rajnarayanan RV, Alworth WL, Hollenberg PF.
    J Pharmacol Exp Ther; 2002 Feb; 300(2):549-58. PubMed ID: 11805216
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  • 11. Metabolism of N,N',N"-triethylenethiophosphoramide by CYP2B1 and CYP2B6 results in the inactivation of both isoforms by two distinct mechanisms.
    Harleton E, Webster M, Bumpus NN, Kent UM, Rae JM, Hollenberg PF.
    J Pharmacol Exp Ther; 2004 Sep; 310(3):1011-9. PubMed ID: 15121764
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  • 12. Synthesis of substituted phenyl diaziridines and characterization as mechanism-based inactivators of human cytochrome P450 2B6.
    Sridar C, Kobayashi Y, Brevig H, Kent UM, Puppali SG, Rimoldi JM, Hollenberg PF.
    Drug Metab Dispos; 2006 Nov; 34(11):1849-55. PubMed ID: 16882766
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  • 14. Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1.
    Goosen TC, Mills DE, Hollenberg PF.
    J Pharmacol Exp Ther; 2001 Jan; 296(1):198-206. PubMed ID: 11123381
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  • 16. Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486).
    He K, Woolf TF, Hollenberg PF.
    J Pharmacol Exp Ther; 1999 Feb; 288(2):791-7. PubMed ID: 9918590
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  • 17. Mechanism-based inactivation of cytochrome P450 2B6 by a novel terminal acetylene inhibitor.
    Fan PW, Gu C, Marsh SA, Stevens JC.
    Drug Metab Dispos; 2003 Jan; 31(1):28-36. PubMed ID: 12485950
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  • 18. Mechanism-based inactivation of cytochrome P450 2B6 by methadone through destruction of prosthetic heme.
    Amunugama HT, Zhang H, Hollenberg PF.
    Drug Metab Dispos; 2012 Sep; 40(9):1765-70. PubMed ID: 22685215
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  • 20. The licorice root derived isoflavan glabridin inhibits the activities of human cytochrome P450S 3A4, 2B6, and 2C9.
    Kent UM, Aviram M, Rosenblat M, Hollenberg PF.
    Drug Metab Dispos; 2002 Jun; 30(6):709-15. PubMed ID: 12019199
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