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Journal Abstract Search

404 related items for PubMed ID: 15608078

  • 21. Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.
    Mikó T, Ligneau X, Pertz HH, Ganellin CR, Arrang JM, Schwartz JC, Schunack W, Stark H.
    J Med Chem; 2003 Apr 10; 46(8):1523-30. PubMed ID: 12672253
    [Abstract] [Full Text] [Related]

  • 22. Importance of the lipophilic group in carbamates having histamine H3-receptor antagonist activity.
    Kieć-Kononowicz K, Wiecek M, Sasse A, Ligneau X, Elz S, Ganellin CR, Schwartz JC, Stark H, Schunack W.
    Pharmazie; 2000 May 10; 55(5):349-55. PubMed ID: 11828613
    [Abstract] [Full Text] [Related]

  • 23. Development of trans-2-[1H-imidazol-4-yl] cyclopropane derivatives as new high-affinity histamine H3 receptor ligands.
    Tedford CE, Phillips JG, Gregory R, Pawlowski GP, Fadnis L, Khan MA, Ali SM, Handley MK, Yates SL.
    J Pharmacol Exp Ther; 1999 May 10; 289(2):1160-8. PubMed ID: 10215700
    [Abstract] [Full Text] [Related]

  • 24. Structurally novel histamine H3 receptor antagonists GSK207040 and GSK334429 improve scopolamine-induced memory impairment and capsaicin-induced secondary allodynia in rats.
    Medhurst AD, Briggs MA, Bruton G, Calver AR, Chessell I, Crook B, Davis JB, Davis RP, Foley AG, Heslop T, Hirst WD, Medhurst SJ, Ociepka S, Ray A, Regan CM, Sargent B, Schogger J, Stean TO, Trail BK, Upton N, White T, Orlek B, Wilson DM.
    Biochem Pharmacol; 2007 Apr 15; 73(8):1182-94. PubMed ID: 17276409
    [Abstract] [Full Text] [Related]

  • 25. Search for novel leads for histamine H3-receptor antagonists: amine derivatives.
    Stark H, Ligneau X, Lipp R, Arrang JM, Schwartz JC, Schunack W.
    Pharmazie; 1997 Jun 15; 52(6):419-23. PubMed ID: 9260265
    [Abstract] [Full Text] [Related]

  • 26. Detection of multiple H3 receptor affinity states utilizing [3H]A-349821, a novel, selective, non-imidazole histamine H3 receptor inverse agonist radioligand.
    Witte DG, Yao BB, Miller TR, Carr TL, Cassar S, Sharma R, Faghih R, Surber BW, Esbenshade TA, Hancock AA, Krueger KM.
    Br J Pharmacol; 2006 Jul 15; 148(5):657-70. PubMed ID: 16715122
    [Abstract] [Full Text] [Related]

  • 27. Histamine H3-receptor-mediated [35S]GTP gamma[S] binding: evidence for constitutive activity of the recombinant and native rat and human H3 receptors.
    Rouleau A, Ligneau X, Tardivel-Lacombe J, Morisset S, Gbahou F, Schwartz JC, Arrang JM.
    Br J Pharmacol; 2002 Jan 15; 135(2):383-92. PubMed ID: 11815373
    [Abstract] [Full Text] [Related]

  • 28. Discovery of histamine H3 receptor antagonistic property of simple imidazole-free derivatives: Preliminary pharmacological investigation.
    Barocelli E, Ballabeni V, Manenti V, Flammini L, Bertoni S, Morini G, Comini M, Impicciatore M.
    Pharmacol Res; 2006 Mar 15; 53(3):226-32. PubMed ID: 16364652
    [Abstract] [Full Text] [Related]

  • 29. Pharmacological analysis of G-protein activation mediated by guinea-pig recombinant 5-HT1B receptors in C6-glial cells: similarities with the human 5-HT1B receptor.
    Pauwels PJ, Wurch T, Palmier C, Colpaert FC.
    Br J Pharmacol; 1998 Jan 15; 123(1):51-62. PubMed ID: 9484854
    [Abstract] [Full Text] [Related]

  • 30. Evaluation of the receptor selectivity of the H3 receptor antagonists, iodophenpropit and thioperamide: an interaction with the 5-HT3 receptor revealed.
    Leurs R, Tulp MT, Menge WM, Adolfs MJ, Zuiderveld OP, Timmerman H.
    Br J Pharmacol; 1995 Oct 15; 116(4):2315-21. PubMed ID: 8564266
    [Abstract] [Full Text] [Related]

  • 31. GSK189254, a novel H3 receptor antagonist that binds to histamine H3 receptors in Alzheimer's disease brain and improves cognitive performance in preclinical models.
    Medhurst AD, Atkins AR, Beresford IJ, Brackenborough K, Briggs MA, Calver AR, Cilia J, Cluderay JE, Crook B, Davis JB, Davis RK, Davis RP, Dawson LA, Foley AG, Gartlon J, Gonzalez MI, Heslop T, Hirst WD, Jennings C, Jones DN, Lacroix LP, Martyn A, Ociepka S, Ray A, Regan CM, Roberts JC, Schogger J, Southam E, Stean TO, Trail BK, Upton N, Wadsworth G, Wald JA, White T, Witherington J, Woolley ML, Worby A, Wilson DM.
    J Pharmacol Exp Ther; 2007 Jun 15; 321(3):1032-45. PubMed ID: 17327487
    [Abstract] [Full Text] [Related]

  • 32. Search for novel leads for histamine H3-receptor antagonists: oxygen-containing derivatives.
    Stark H, Hüls A, Ligneau X, Arrang JM, Schwartz JC, Schunack W.
    Pharmazie; 1997 Jul 15; 52(7):495-500. PubMed ID: 9266588
    [Abstract] [Full Text] [Related]

  • 33. Effects of clozapine on rat striatal muscarinic receptors coupled to inhibition of adenylyl cyclase activity and on the human cloned m4 receptor.
    Olianas MC, Maullu C, Onali P.
    Br J Pharmacol; 1997 Oct 15; 122(3):401-8. PubMed ID: 9351494
    [Abstract] [Full Text] [Related]

  • 34. Piperidine-containing histamine H3 receptor antagonists of the carbamate series: the influence of the additional ether functionality.
    Łazewska D, Kieć-Kononowicz K, Pertz HH, Elz S, Stark H, Schunack W.
    Pharmazie; 2002 Dec 15; 57(12):791-5. PubMed ID: 12561236
    [Abstract] [Full Text] [Related]

  • 35. The histamine H3 receptor antagonist clobenpropit enhances GABA release to protect against NMDA-induced excitotoxicity through the cAMP/protein kinase A pathway in cultured cortical neurons.
    Dai H, Fu Q, Shen Y, Hu W, Zhang Z, Timmerman H, Leurs R, Chen Z.
    Eur J Pharmacol; 2007 Jun 01; 563(1-3):117-23. PubMed ID: 17350613
    [Abstract] [Full Text] [Related]

  • 36. High antagonist potency of GT-2227 and GT-2331, new histamine H3 receptor antagonists, in two functional models.
    Tedford CE, Hoffmann M, Seyedi N, Maruyama R, Levi R, Yates SL, Ali SM, Phillips JG.
    Eur J Pharmacol; 1998 Jun 26; 351(3):307-11. PubMed ID: 9721022
    [Abstract] [Full Text] [Related]

  • 37. Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs.
    Zhang M, Ballard ME, Pan L, Roberts S, Faghih R, Cowart M, Esbenshade TA, Fox GB, Decker MW, Hancock AA, Rueter LE.
    Brain Res; 2005 May 31; 1045(1-2):142-9. PubMed ID: 15910772
    [Abstract] [Full Text] [Related]

  • 38. Histamine homologues discriminating between two functional H3 receptor assays. Evidence for H3 receptor heterogeneity?
    Leurs R, Kathmann M, Vollinga RC, Menge WM, Schlicker E, Timmerman H.
    J Pharmacol Exp Ther; 1996 Mar 31; 276(3):1009-15. PubMed ID: 8786529
    [Abstract] [Full Text] [Related]

  • 39. Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies.
    Tedford CE, Yates SL, Pawlowski GP, Nalwalk JW, Hough LB, Khan MA, Phillips JG, Durant GJ, Frederickson RC.
    J Pharmacol Exp Ther; 1995 Nov 31; 275(2):598-604. PubMed ID: 7473144
    [Abstract] [Full Text] [Related]

  • 40. Design, synthesis, and structure-activity relationships of novel non-imidazole histamine H(3) receptor antagonists.
    Linney ID, Buck IM, Harper EA, Kalindjian SB, Pether MJ, Shankley NP, Watt GF, Wright PT.
    J Med Chem; 2000 Jun 15; 43(12):2362-70. PubMed ID: 10882362
    [Abstract] [Full Text] [Related]

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