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490 related items for PubMed ID: 15618475

  • 1. Flt3 ligand and the Flt3 receptor regulate hematopoietic cell migration by modulating the SDF-1alpha(CXCL12)/CXCR4 axis.
    Fukuda S, Broxmeyer HE, Pelus LM.
    Blood; 2005 Apr 15; 105(8):3117-26. PubMed ID: 15618475
    [Abstract] [Full Text] [Related]

  • 2. Binding of stromal derived factor-1alpha (SDF-1alpha) to CXCR4 chemokine receptor in normal human megakaryoblasts but not in platelets induces phosphorylation of mitogen-activated protein kinase p42/44 (MAPK), ELK-1 transcription factor and serine/threonine kinase AKT.
    Majka M, Ratajczak J, Kowalska MA, Ratajczak MZ.
    Eur J Haematol; 2000 Mar 15; 64(3):164-72. PubMed ID: 10997882
    [Abstract] [Full Text] [Related]

  • 3. Internal tandem duplication of Flt3 modulates chemotaxis and survival of hematopoietic cells by SDF1alpha but negatively regulates marrow homing in vivo.
    Fukuda S, Pelus LM.
    Exp Hematol; 2006 Aug 15; 34(8):1041-51. PubMed ID: 16863910
    [Abstract] [Full Text] [Related]

  • 4. Incorporation of CXCR4 into membrane lipid rafts primes homing-related responses of hematopoietic stem/progenitor cells to an SDF-1 gradient.
    Wysoczynski M, Reca R, Ratajczak J, Kucia M, Shirvaikar N, Honczarenko M, Mills M, Wanzeck J, Janowska-Wieczorek A, Ratajczak MZ.
    Blood; 2005 Jan 01; 105(1):40-8. PubMed ID: 15328152
    [Abstract] [Full Text] [Related]

  • 5. Akt activation, but not extracellular signal-regulated kinase activation, is required for SDF-1alpha/CXCR4-mediated migration of epitheloid carcinoma cells.
    Peng SB, Peek V, Zhai Y, Paul DC, Lou Q, Xia X, Eessalu T, Kohn W, Tang S.
    Mol Cancer Res; 2005 Apr 01; 3(4):227-36. PubMed ID: 15831676
    [Abstract] [Full Text] [Related]

  • 6. The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways.
    Ganju RK, Brubaker SA, Meyer J, Dutt P, Yang Y, Qin S, Newman W, Groopman JE.
    J Biol Chem; 1998 Sep 04; 273(36):23169-75. PubMed ID: 9722546
    [Abstract] [Full Text] [Related]

  • 7. The FLT3 internal tandem duplication mutation prevents apoptosis in interleukin-3-deprived BaF3 cells due to protein kinase A and ribosomal S6 kinase 1-mediated BAD phosphorylation at serine 112.
    Yang X, Liu L, Sternberg D, Tang L, Galinsky I, DeAngelo D, Stone R.
    Cancer Res; 2005 Aug 15; 65(16):7338-47. PubMed ID: 16103085
    [Abstract] [Full Text] [Related]

  • 8. Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of the Rho-associated kinase via the Cxcl12/Cxcr4 signaling axis.
    Onishi C, Mori-Kimachi S, Hirade T, Abe M, Taketani T, Suzumiya J, Sugimoto T, Yamaguchi S, Kapur R, Fukuda S.
    J Biol Chem; 2014 Nov 07; 289(45):31053-65. PubMed ID: 25237195
    [Abstract] [Full Text] [Related]

  • 9. Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells.
    Kijima T, Maulik G, Ma PC, Tibaldi EV, Turner RE, Rollins B, Sattler M, Johnson BE, Salgia R.
    Cancer Res; 2002 Nov 01; 62(21):6304-11. PubMed ID: 12414661
    [Abstract] [Full Text] [Related]

  • 10. Impact of CXCR4 inhibition on FLT3-ITD-positive human AML blasts.
    Jacobi A, Thieme S, Lehmann R, Ugarte F, Malech HL, Koch S, Thiede C, Müller K, Bornhäuser M, Ryser M, Brenner S.
    Exp Hematol; 2010 Mar 01; 38(3):180-90. PubMed ID: 20035824
    [Abstract] [Full Text] [Related]

  • 11. Stromal cell-derived factor 1alpha stimulates human glioblastoma cell growth through the activation of both extracellular signal-regulated kinases 1/2 and Akt.
    Barbero S, Bonavia R, Bajetto A, Porcile C, Pirani P, Ravetti JL, Zona GL, Spaziante R, Florio T, Schettini G.
    Cancer Res; 2003 Apr 15; 63(8):1969-74. PubMed ID: 12702590
    [Abstract] [Full Text] [Related]

  • 12. Stromal cell-derived factor-1alpha stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: roles of phosphoinositide-3 kinase and protein kinase C.
    Wang JF, Park IW, Groopman JE.
    Blood; 2000 Apr 15; 95(8):2505-13. PubMed ID: 10753828
    [Abstract] [Full Text] [Related]

  • 13. Janus kinase 2 is involved in stromal cell-derived factor-1alpha-induced tyrosine phosphorylation of focal adhesion proteins and migration of hematopoietic progenitor cells.
    Zhang XF, Wang JF, Matczak E, Proper JA, Groopman JE.
    Blood; 2001 Jun 01; 97(11):3342-8. PubMed ID: 11369622
    [Abstract] [Full Text] [Related]

  • 14. The stromal cell-derived factor-1alpha/CXCR4 ligand-receptor axis is critical for progenitor survival and migration in the pancreas.
    Kayali AG, Van Gunst K, Campbell IL, Stotland A, Kritzik M, Liu G, Flodström-Tullberg M, Zhang YQ, Sarvetnick N.
    J Cell Biol; 2003 Nov 24; 163(4):859-69. PubMed ID: 14638861
    [Abstract] [Full Text] [Related]

  • 15. The SDF-1-CXCR4 axis stimulates VEGF secretion and activates integrins but does not affect proliferation and survival in lymphohematopoietic cells.
    Kijowski J, Baj-Krzyworzeka M, Majka M, Reca R, Marquez LA, Christofidou-Solomidou M, Janowska-Wieczorek A, Ratajczak MZ.
    Stem Cells; 2001 Nov 24; 19(5):453-66. PubMed ID: 11553854
    [Abstract] [Full Text] [Related]

  • 16. Up-regulation of CXCR4 expression in PC-3 cells by stromal-derived factor-1alpha (CXCL12) increases endothelial adhesion and transendothelial migration: role of MEK/ERK signaling pathway-dependent NF-kappaB activation.
    Kukreja P, Abdel-Mageed AB, Mondal D, Liu K, Agrawal KC.
    Cancer Res; 2005 Nov 01; 65(21):9891-8. PubMed ID: 16267013
    [Abstract] [Full Text] [Related]

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  • 18. Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45.
    Fernandis AZ, Cherla RP, Ganju RK.
    J Biol Chem; 2003 Mar 14; 278(11):9536-43. PubMed ID: 12519755
    [Abstract] [Full Text] [Related]

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  • 20. Selective cytotoxic mechanism of GTP-14564, a novel tyrosine kinase inhibitor in leukemia cells expressing a constitutively active Fms-like tyrosine kinase 3 (FLT3).
    Murata K, Kumagai H, Kawashima T, Tamitsu K, Irie M, Nakajima H, Suzu S, Shibuya M, Kamihira S, Nosaka T, Asano S, Kitamura T.
    J Biol Chem; 2003 Aug 29; 278(35):32892-8. PubMed ID: 12815052
    [Abstract] [Full Text] [Related]

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