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Journal Abstract Search
734 related items for PubMed ID: 15625077
1. HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage. Pääjärvi G, Roudier E, Crisby M, Högberg J, Stenius U. FASEB J; 2005 Mar; 19(3):476-8. PubMed ID: 15625077 [Abstract] [Full Text] [Related]
2. Statins induce mammalian target of rapamycin (mTOR)-mediated inhibition of Akt signaling and sensitize p53-deficient cells to cytostatic drugs. Roudier E, Mistafa O, Stenius U. Mol Cancer Ther; 2006 Nov; 5(11):2706-15. PubMed ID: 17121917 [Abstract] [Full Text] [Related]
3. TCDD activates Mdm2 and attenuates the p53 response to DNA damaging agents. Pääjärvi G, Viluksela M, Pohjanvirta R, Stenius U, Högberg J. Carcinogenesis; 2005 Jan; 26(1):201-8. PubMed ID: 15459018 [Abstract] [Full Text] [Related]
4. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage. Maya R, Balass M, Kim ST, Shkedy D, Leal JF, Shifman O, Moas M, Buschmann T, Ronai Z, Shiloh Y, Kastan MB, Katzir E, Oren M. Genes Dev; 2001 May 01; 15(9):1067-77. PubMed ID: 11331603 [Abstract] [Full Text] [Related]
5. Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling. Nakao T, Shiota M, Tatemoto Y, Izumi Y, Iwao H. J Pharmacol Sci; 2007 Dec 01; 105(4):334-41. PubMed ID: 18057776 [Abstract] [Full Text] [Related]
6. Akt enhances Mdm2-mediated ubiquitination and degradation of p53. Ogawara Y, Kishishita S, Obata T, Isazawa Y, Suzuki T, Tanaka K, Masuyama N, Gotoh Y. J Biol Chem; 2002 Jun 14; 277(24):21843-50. PubMed ID: 11923280 [Abstract] [Full Text] [Related]
7. Reduced ATM kinase activity and an attenuated p53 response to DNA damage in carcinogen-induced preneoplastic hepatic lesions in the rat. Silins I, Finnberg N, Ståhl A, Högberg J, Stenius U. Carcinogenesis; 2001 Dec 14; 22(12):2023-31. PubMed ID: 11751435 [Abstract] [Full Text] [Related]
8. Phage-peptide display identifies the interferon-responsive, death-activated protein kinase family as a novel modifier of MDM2 and p21WAF1. Burch LR, Scott M, Pohler E, Meek D, Hupp T. J Mol Biol; 2004 Mar 12; 337(1):115-28. PubMed ID: 15001356 [Abstract] [Full Text] [Related]
9. Role of polyamines in p53-dependent apoptosis of intestinal epithelial cells. Bhattacharya S, Ray RM, Johnson LR. Cell Signal; 2009 Apr 12; 21(4):509-22. PubMed ID: 19136059 [Abstract] [Full Text] [Related]
10. HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Zhou BP, Liao Y, Xia W, Zou Y, Spohn B, Hung MC. Nat Cell Biol; 2001 Nov 12; 3(11):973-82. PubMed ID: 11715018 [Abstract] [Full Text] [Related]
11. Characterizing the role of MDM2 in diethylnitrosamine induced acute liver damage and development of pre-neoplastic lesions. Finnberg N, Silins I, Stenius U, Högberg J. Carcinogenesis; 2004 Jan 12; 25(1):113-22. PubMed ID: 14555611 [Abstract] [Full Text] [Related]
12. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage. Chen L, Gilkes DM, Pan Y, Lane WS, Chen J. EMBO J; 2005 Oct 05; 24(19):3411-22. PubMed ID: 16163388 [Abstract] [Full Text] [Related]
13. Functional role of Mdm2 phosphorylation by ATR in attenuation of p53 nuclear export. Shinozaki T, Nota A, Taya Y, Okamoto K. Oncogene; 2003 Dec 04; 22(55):8870-80. PubMed ID: 14654783 [Abstract] [Full Text] [Related]
14. Status of p53 phosphorylation and function in sensitive and resistant human cancer models exposed to platinum-based DNA damaging agents. Mujoo K, Watanabe M, Nakamura J, Khokhar AR, Siddik ZH. J Cancer Res Clin Oncol; 2003 Dec 04; 129(12):709-18. PubMed ID: 14513366 [Abstract] [Full Text] [Related]
15. Apoptotic injury in cultured human hepatocytes induced by HMG-CoA reductase inhibitors. Kubota T, Fujisaki K, Itoh Y, Yano T, Sendo T, Oishi R. Biochem Pharmacol; 2004 Jun 15; 67(12):2175-86. PubMed ID: 15163549 [Abstract] [Full Text] [Related]
16. Glycogen synthase kinase 3-dependent phosphorylation of Mdm2 regulates p53 abundance. Kulikov R, Boehme KA, Blattner C. Mol Cell Biol; 2005 Aug 15; 25(16):7170-80. PubMed ID: 16055726 [Abstract] [Full Text] [Related]
17. Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation. Tang J, Agrawal T, Cheng Q, Qu L, Brewer MD, Chen J, Yang X. PLoS One; 2013 Aug 15; 8(2):e55813. PubMed ID: 23405218 [Abstract] [Full Text] [Related]
18. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells. Brew CT, Aronchik I, Hsu JC, Sheen JH, Dickson RB, Bjeldanes LF, Firestone GL. Int J Cancer; 2006 Feb 15; 118(4):857-68. PubMed ID: 16152627 [Abstract] [Full Text] [Related]
19. Loss of nuclear p53 protein in preneoplastic rat hepatocytes is accompanied by Mdm2 and Bcl-2 overexpression and by defective response to DNA damage in vivo. Van Gijssel HE, Ohlson LC, Torndal UB, Mulder GJ, Eriksson LC, Porsch-Hällström I, Meerman JH. Hepatology; 2000 Oct 15; 32(4 Pt 1):701-10. PubMed ID: 11003613 [Abstract] [Full Text] [Related]
20. Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells. Yang Y, Ludwig RL, Jensen JP, Pierre SA, Medaglia MV, Davydov IV, Safiran YJ, Oberoi P, Kenten JH, Phillips AC, Weissman AM, Vousden KH. Cancer Cell; 2005 Jun 15; 7(6):547-59. PubMed ID: 15950904 [Abstract] [Full Text] [Related] Page: [Next] [New Search]