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255 related items for PubMed ID: 15632825

  • 1. Induction of apoptosis of lung and esophageal cancer cells treated with the combination of histone deacetylase inhibitor (trichostatin A) and protein kinase C inhibitor (calphostin C).
    Maxhimer JB, Reddy RM, Zuo J, Cole GW, Schrump DS, Nguyen DM.
    J Thorac Cardiovasc Surg; 2005 Jan; 129(1):53-63. PubMed ID: 15632825
    [Abstract] [Full Text] [Related]

  • 2. Potentiation of paclitaxel cytotoxicity in lung and esophageal cancer cells by pharmacologic inhibition of the phosphoinositide 3-kinase/protein kinase B (Akt)-mediated signaling pathway.
    Nguyen DM, Chen GA, Reddy R, Tsai W, Schrump WD, Cole G, Schrump DS.
    J Thorac Cardiovasc Surg; 2004 Feb; 127(2):365-75. PubMed ID: 14762343
    [Abstract] [Full Text] [Related]

  • 3. Induction of caspase mediated apoptosis and down-regulation of nuclear factor-κB and Akt signaling are involved in the synergistic antitumor effect of gemcitabine and the histone deacetylase inhibitor trichostatin A in human bladder cancer cells.
    Jeon HG, Yoon CY, Yu JH, Park MJ, Lee JE, Jeong SJ, Hong SK, Byun SS, Lee SE.
    J Urol; 2011 Nov; 186(5):2084-93. PubMed ID: 21944112
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of phosphatidylinositol 3-kinase/Akt and histone deacetylase activity induces apoptosis in non-small cell lung cancer in vitro and in vivo.
    Denlinger CE, Rundall BK, Jones DR.
    J Thorac Cardiovasc Surg; 2005 Nov; 130(5):1422-9. PubMed ID: 16256798
    [Abstract] [Full Text] [Related]

  • 5. Combined proteasome and histone deacetylase inhibition in non-small cell lung cancer.
    Denlinger CE, Keller MD, Mayo MW, Broad RM, Jones DR.
    J Thorac Cardiovasc Surg; 2004 Apr; 127(4):1078-86. PubMed ID: 15052205
    [Abstract] [Full Text] [Related]

  • 6. The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways.
    Hrgovic I, Doll M, Kleemann J, Wang XF, Zoeller N, Pinter A, Kippenberger S, Kaufmann R, Meissner M.
    BMC Cancer; 2016 Sep 30; 16(1):763. PubMed ID: 27716272
    [Abstract] [Full Text] [Related]

  • 7. ERK inhibition enhances TSA-induced gastric cancer cell apoptosis via NF-κB-dependent and Notch-independent mechanism.
    Yao J, Qian CJ, Ye B, Zhang X, Liang Y.
    Life Sci; 2012 Sep 04; 91(5-6):186-93. PubMed ID: 22781708
    [Abstract] [Full Text] [Related]

  • 8. Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells.
    Domingo-Domènech J, Pippa R, Tápia M, Gascón P, Bachs O, Bosch M.
    Breast Cancer Res Treat; 2008 Nov 04; 112(1):53-62. PubMed ID: 18064564
    [Abstract] [Full Text] [Related]

  • 9. Enhancement of depsipeptide-mediated apoptosis of lung or esophageal cancer cells by flavopiridol: activation of the mitochondria-dependent death-signaling pathway.
    Nguyen DM, Schrump WD, Tsai WS, Chen A, Stewart JH, Steiner F, Schrump DS.
    J Thorac Cardiovasc Surg; 2003 May 04; 125(5):1132-42. PubMed ID: 12771887
    [Abstract] [Full Text] [Related]

  • 10. Proteasome inhibition sensitizes non-small cell lung cancer to histone deacetylase inhibitor-induced apoptosis through the generation of reactive oxygen species.
    Denlinger CE, Rundall BK, Jones DR.
    J Thorac Cardiovasc Surg; 2004 Nov 04; 128(5):740-8. PubMed ID: 15514602
    [Abstract] [Full Text] [Related]

  • 11. Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01.
    Yeow WS, Ziauddin MF, Maxhimer JB, Shamimi-Noori S, Baras A, Chua A, Schrump DS, Nguyen DM.
    Br J Cancer; 2006 May 22; 94(10):1436-45. PubMed ID: 16705314
    [Abstract] [Full Text] [Related]

  • 12. Contribution of disruption of the nuclear factor-kappaB pathway to induction of apoptosis in human leukemia cells by histone deacetylase inhibitors and flavopiridol.
    Gao N, Dai Y, Rahmani M, Dent P, Grant S.
    Mol Pharmacol; 2004 Oct 22; 66(4):956-63. PubMed ID: 15235103
    [Abstract] [Full Text] [Related]

  • 13. Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells.
    Rokhlin OW, Glover RB, Guseva NV, Taghiyev AF, Kohlgraf KG, Cohen MB.
    Mol Cancer Res; 2006 Feb 22; 4(2):113-23. PubMed ID: 16513842
    [Abstract] [Full Text] [Related]

  • 14. Histone deacetylase inhibition down-regulates cyclin D1 transcription by inhibiting nuclear factor-kappaB/p65 DNA binding.
    Hu J, Colburn NH.
    Mol Cancer Res; 2005 Feb 22; 3(2):100-9. PubMed ID: 15755876
    [Abstract] [Full Text] [Related]

  • 15. Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB.
    Menendez JA, Mehmi I, Atlas E, Colomer R, Lupu R.
    Int J Oncol; 2004 Mar 22; 24(3):591-608. PubMed ID: 14767544
    [Abstract] [Full Text] [Related]

  • 16. Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and promotes apoptosis of esophageal squamous cell lines.
    Ma J, Guo X, Zhang S, Liu H, Lu J, Dong Z, Liu K, Ming L.
    Mol Med Rep; 2015 Jun 22; 11(6):4525-31. PubMed ID: 25634603
    [Abstract] [Full Text] [Related]

  • 17. The novel histone deacetylase inhibitor, N-hydroxy-7-(2-naphthylthio) hepatonomide, exhibits potent antitumor activity due to cytochrome-c-release-mediated apoptosis in renal cell carcinoma cells.
    Park KC, Heo JH, Jeon JY, Choi HJ, Jo AR, Kim SW, Kwon HJ, Hong SJ, Han KS.
    BMC Cancer; 2015 Jan 23; 15():19. PubMed ID: 25613585
    [Abstract] [Full Text] [Related]

  • 18. Effectiveness of trichostatin A as a potential candidate for anticancer therapy in non-small-cell lung cancer.
    Mukhopadhyay NK, Weisberg E, Gilchrist D, Bueno R, Sugarbaker DJ, Jaklitsch MT.
    Ann Thorac Surg; 2006 Mar 23; 81(3):1034-42. PubMed ID: 16488717
    [Abstract] [Full Text] [Related]

  • 19. HDAC inhibitor-induced activation of NF-κB prevents apoptotic response of E1A+Ras-transformed cells to proapoptotic stimuli.
    Abramova MV, Zatulovskiy EA, Svetlikova SB, Pospelov VA.
    Int J Biochem Cell Biol; 2010 Nov 23; 42(11):1847-55. PubMed ID: 20692358
    [Abstract] [Full Text] [Related]

  • 20. Histone deacetylase inhibitors induce growth arrest and apoptosis of HTLV-1-infected T-cells via blockade of signaling by nuclear factor kappaB.
    Nishioka C, Ikezoe T, Yang J, Komatsu N, Bandobashi K, Taniguchi A, Kuwayama Y, Togitani K, Koeffler HP, Taguchi H.
    Leuk Res; 2008 Feb 23; 32(2):287-96. PubMed ID: 17644177
    [Abstract] [Full Text] [Related]

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