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Journal Abstract Search

215 related items for PubMed ID: 15640355

  • 1. The carboligation reaction of acetohydroxyacid synthase II: steady-state intermediate distributions in wild type and mutants by NMR.
    Tittmann K, Vyazmensky M, Hübner G, Barak Z, Chipman DM.
    Proc Natl Acad Sci U S A; 2005 Jan 18; 102(3):553-8. PubMed ID: 15640355
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  • 3. Significant catalytic roles for Glu47 and Gln 110 in all four of the C-C bond-making and -breaking steps of the reactions of acetohydroxyacid synthase II.
    Vyazmensky M, Steinmetz A, Meyer D, Golbik R, Barak Z, Tittmann K, Chipman DM.
    Biochemistry; 2011 Apr 19; 50(15):3250-60. PubMed ID: 21370850
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  • 4. Valine 375 and phenylalanine 109 confer affinity and specificity for pyruvate as donor substrate in acetohydroxy acid synthase isozyme II from Escherichia coli.
    Steinmetz A, Vyazmensky M, Meyer D, Barak ZE, Golbik R, Chipman DM, Tittmann K.
    Biochemistry; 2010 Jun 29; 49(25):5188-99. PubMed ID: 20504042
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  • 5. Role of a conserved arginine in the mechanism of acetohydroxyacid synthase: catalysis of condensation with a specific ketoacid substrate.
    Engel S, Vyazmensky M, Vinogradov M, Berkovich D, Bar-Ilan A, Qimron U, Rosiansky Y, Barak Z, Chipman DM.
    J Biol Chem; 2004 Jun 04; 279(23):24803-12. PubMed ID: 15044456
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  • 8. Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. Implications for the reactivity and partitioning of the carbanion/enamine form of (alpha-hydroxyethyl)thiamin diphosphate in a "nonredox" flavoenzyme.
    Tittmann K, Schröder K, Golbik R, McCourt J, Kaplun A, Duggleby RG, Barak Z, Chipman DM, Hübner G.
    Biochemistry; 2004 Jul 13; 43(27):8652-61. PubMed ID: 15236573
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  • 9. Intermediates and transition states in thiamin diphosphate-dependent decarboxylases. A kinetic and NMR study on wild-type indolepyruvate decarboxylase and variants using indolepyruvate, benzoylformate, and pyruvate as substrates.
    Schütz A, Golbik R, König S, Hübner G, Tittmann K.
    Biochemistry; 2005 Apr 26; 44(16):6164-79. PubMed ID: 15835904
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  • 12. A QM/MM study on the reaction pathway leading to 2-aceto-2-hydroxybutyrate in the catalytic cycle of AHAS.
    Sánchez L, Jaña GA, Delgado EJ.
    J Comput Chem; 2014 Mar 05; 35(6):488-94. PubMed ID: 24395707
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  • 13. Mutations in the regulatory subunit of yeast acetohydroxyacid synthase affect its activation by MgATP.
    Lee YT, Duggleby RG.
    Biochem J; 2006 Apr 15; 395(2):331-6. PubMed ID: 16390333
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  • 16. Structure of the regulatory subunit of acetohydroxyacid synthase isozyme III from Escherichia coli.
    Kaplun A, Vyazmensky M, Zherdev Y, Belenky I, Slutzker A, Mendel S, Barak Z, Chipman DM, Shaanan B.
    J Mol Biol; 2006 Mar 31; 357(3):951-63. PubMed ID: 16458324
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  • 17. Acetohydroxyacid synthase and its role in the biosynthetic pathway for branched-chain amino acids.
    McCourt JA, Duggleby RG.
    Amino Acids; 2006 Sep 31; 31(2):173-210. PubMed ID: 16699828
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  • 18. Identification of the catalytic subunit of acetohydroxyacid synthase in Haemophilus influenzae and its potent inhibitors.
    Choi KJ, Noh KM, Kim DE, Ha BH, Kim EE, Yoon MY.
    Arch Biochem Biophys; 2007 Oct 01; 466(1):24-30. PubMed ID: 17718999
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  • 19. Computational determination of fundamental pathway and activation barriers for acetohydroxyacid synthase-catalyzed condensation reactions of alpha-keto acids.
    Xiong Y, Liu J, Yang GF, Zhan CG.
    J Comput Chem; 2010 Jun 01; 31(8):1592-602. PubMed ID: 19554557
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  • 20. Acetohydroxyacid synthase: a proposed structure for regulatory subunits supported by evidence from mutagenesis.
    Mendel S, Elkayam T, Sella C, Vinogradov V, Vyazmensky M, Chipman DM, Barak Z.
    J Mol Biol; 2001 Mar 16; 307(1):465-77. PubMed ID: 11243831
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