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163 related items for PubMed ID: 15640373

  • 1. Characterization and partial purification of the rat and human enzyme systems active in the reduction of N-hydroxymelagatran and benzamidoxime.
    Andersson S, Hofmann Y, Nordling A, Li XQ, Nivelius S, Andersson TB, Ingelman-Sundberg M, Johansson I.
    Drug Metab Dispos; 2005 Apr; 33(4):570-8. PubMed ID: 15640373
    [Abstract] [Full Text] [Related]

  • 2. Hepatic, extrahepatic, microsomal, and mitochondrial activation of the N-hydroxylated prodrugs benzamidoxime, guanoxabenz, and Ro 48-3656 ([[1-[(2s)-2-[[4-[(hydroxyamino)iminomethyl]benzoyl]amino]-1-oxopropyl]-4-piperidinyl]oxy]-acetic acid).
    Clement B, Mau S, Deters S, Havemeyer A.
    Drug Metab Dispos; 2005 Nov; 33(11):1740-7. PubMed ID: 16118330
    [Abstract] [Full Text] [Related]

  • 3. Reduction of amphetamine hydroxylamine and other aliphatic hydroxylamines by benzamidoxime reductase and human liver microsomes.
    Clement B, Behrens D, Möller W, Cashman JR.
    Chem Res Toxicol; 2000 Oct; 13(10):1037-45. PubMed ID: 11080052
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  • 8. Characteristics of the microsomal N-hydroxylation of benzamidine to benzamidoxime.
    Clement B, Zimmermann M.
    Xenobiotica; 1987 Jun; 17(6):659-67. PubMed ID: 3630202
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  • 9. The fourth molybdenum containing enzyme mARC: cloning and involvement in the activation of N-hydroxylated prodrugs.
    Gruenewald S, Wahl B, Bittner F, Hungeling H, Kanzow S, Kotthaus J, Schwering U, Mendel RR, Clement B.
    J Med Chem; 2008 Dec 25; 51(24):8173-7. PubMed ID: 19053771
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  • 10. Sulfoxidation of cysteine and mercapturic acid conjugates of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A).
    Altuntas TG, Park SB, Kharasch ED.
    Chem Res Toxicol; 2004 Mar 25; 17(3):435-45. PubMed ID: 15025515
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  • 11. Oxidation pattern of the anticancer drug ellipticine by hepatic microsomes - similarity between human and rat systems.
    Stiborová M, Borek-Dohalská L, Aimová D, Kotrbová V, Kukacková K, Janouchová K, Rupertová M, Ryslavá H, Hudecek J, Frei E.
    Gen Physiol Biophys; 2006 Sep 25; 25(3):245-61. PubMed ID: 17197724
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  • 12. Isolation and characterization of the protein components of the liver microsomal O2-insensitive NADH-benzamidoxime reductase.
    Clement B, Lomb R, Möller W.
    J Biol Chem; 1997 Aug 01; 272(31):19615-20. PubMed ID: 9235969
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  • 13. Involvement of stearoyl-CoA desaturase in the reduction of amidoxime prodrugs.
    Reh R, Ozols J, Clement B.
    Xenobiotica; 2008 Sep 01; 38(9):1177-90. PubMed ID: 18609446
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  • 14. Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): comparison with human enzyme analogs.
    Li J, Liu Y, Zhang JW, Wei H, Yang L.
    Comp Med; 2006 Aug 01; 56(4):286-90. PubMed ID: 16941956
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  • 15. Substituent effect on the reductive N-dearylation of 3-(indol-1-yl)-1,2-benzisoxazoles by rat liver microsomes.
    Tschirret-Guth RA, Wood HB.
    Drug Metab Dispos; 2003 Aug 01; 31(8):999-1004. PubMed ID: 12867488
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  • 16. The N-oxidation of benzamidines in vitro.
    Clement B.
    Xenobiotica; 1983 Aug 01; 13(8):467-73. PubMed ID: 6649680
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  • 17. Preparation, purification, and spectrophotometric characterization of cytochrome P450 1A2 conjugated with polyethylene glycol monomethyl ether.
    Nakhgevany R, Bonsu O, Barber J, Mabrouk PA, Ueng YF, Bell LC, Guengerich FP.
    Biochem Biophys Res Commun; 1996 May 15; 222(2):406-9. PubMed ID: 8670218
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  • 18. Reduction of N-hydroxy-sulfonamides, including N-hydroxy-valdecoxib, by the molybdenum-containing enzyme mARC.
    Havemeyer A, Grünewald S, Wahl B, Bittner F, Mendel R, Erdélyi P, Fischer J, Clement B.
    Drug Metab Dispos; 2010 Nov 15; 38(11):1917-21. PubMed ID: 20699408
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  • 19. Characterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes.
    Li W, Liu Y, He YQ, Zhang JW, Gao Y, Ge GB, Liu HX, Huo H, Liu HT, Wang LM, Sun J, Wang Q, Yang L.
    Xenobiotica; 2008 Dec 15; 38(12):1551-65. PubMed ID: 18982531
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  • 20. Development of three parallel cytochrome P450 enzyme affinity detection systems coupled on-line to gradient high-performance liquid chromatography.
    Kool J, van Liempd SM, van Rossum H, van Elswijk DA, Irth H, Commandeur JN, Vermeulen NP.
    Drug Metab Dispos; 2007 Apr 15; 35(4):640-8. PubMed ID: 17251308
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