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Journal Abstract Search

235 related items for PubMed ID: 15652362

  • 21. Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
    Pontiki E, Hadjipavlou-Litina D, Litinas K, Nicolotti O, Carotti A.
    Eur J Med Chem; 2011 Jan; 46(1):191-200. PubMed ID: 21106277
    [Abstract] [Full Text] [Related]

  • 22. Benzodioxole-Pyrazole Hybrids as Anti-Inflammatory and Analgesic Agents with COX-1,2/5-LOX Inhibition and Antioxidant Potential.
    Abd El Razik HA, Badr MH, Atta AH, Mouneir SM, Abu-Serie MM.
    Arch Pharm (Weinheim); 2017 May; 350(5):. PubMed ID: 28418202
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  • 23. Phenidone protects the nigral dopaminergic neurons from LPS-induced neurotoxicity.
    Li Z, Choi DY, Shin EJ, Hunter RL, Jin CH, Wie MB, Kim MS, Park SJ, Bing G, Kim HC.
    Neurosci Lett; 2008 Nov 07; 445(1):1-6. PubMed ID: 18760329
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  • 24. Synthesis and SAR/3D-QSAR studies on the COX-2 inhibitory activity of 1,5-diarylpyrazoles to validate the modified pharmacophore.
    Singh SK, Saibaba V, Rao KS, Reddy PG, Daga PR, Rajjak SA, Misra P, Rao YK.
    Eur J Med Chem; 2005 Oct 07; 40(10):977-90. PubMed ID: 15961192
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  • 25. Design, synthesis and biological evaluation of benzo[1.3.2]dithiazolium ylide 1,1-dioxide derivatives as potential dual cyclooxygenase-2/5-lipoxygenase inhibitors.
    Tan CM, Chen GS, Chen CS, Chang PT, Chern JW.
    Bioorg Med Chem; 2011 Nov 01; 19(21):6316-28. PubMed ID: 21958737
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  • 26. Pyrazole-hydrazone derivatives as anti-inflammatory agents: Design, synthesis, biological evaluation, COX-1,2/5-LOX inhibition and docking study.
    Abdelgawad MA, Labib MB, Abdel-Latif M.
    Bioorg Chem; 2017 Oct 01; 74():212-220. PubMed ID: 28865292
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  • 27. Dual inhibition of 5-lipoxygenase/cyclooxygenase by a reconstituted homeopathic remedy; possible explanation for clinical efficacy and favourable gastrointestinal tolerability.
    Jäggi R, Würgler U, Grandjean F, Weiser M.
    Inflamm Res; 2004 Apr 01; 53(4):150-7. PubMed ID: 15060721
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  • 28. COX, LOX and platelet aggregation inhibitory properties of Lauraceae neolignans.
    Coy ED, Cuca LE, Sefkow M.
    Bioorg Med Chem Lett; 2009 Dec 15; 19(24):6922-5. PubMed ID: 19880317
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  • 29. Novel N-substituted 5-aminosalicylamides as dual inhibitors of cyclooxygenase and 5-lipoxygenase enzymes: Synthesis, biological evaluation and docking study.
    El-Nagar MKS, Abdu-Allah HHM, Salem OIA, Kafafy AN, Farghaly HSM.
    Bioorg Chem; 2018 Aug 15; 78():80-93. PubMed ID: 29550533
    [Abstract] [Full Text] [Related]

  • 30. New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.
    El-Miligy MMM, Hazzaa AA, El-Messmary H, Nassra RA, El-Hawash SAM.
    Bioorg Chem; 2017 Jun 15; 72():102-115. PubMed ID: 28390993
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  • 31. Cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) selectivity of COX inhibitors.
    Sud'ina GF, Pushkareva MA, Shephard P, Klein T.
    Prostaglandins Leukot Essent Fatty Acids; 2008 Feb 15; 78(2):99-108. PubMed ID: 18280718
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  • 32. Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities.
    Jahng Y, Zhao LX, Moon YS, Basnet A, Kim EK, Chang HW, Ju HK, Jeong TC, Lee ES.
    Bioorg Med Chem Lett; 2004 May 17; 14(10):2559-62. PubMed ID: 15109651
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  • 33. Synthesis and selective cyclooxygenase-2 inhibitory activity of a series of novel, nitric oxide donor-containing pyrazoles.
    Ranatunge RR, Augustyniak M, Bandarage UK, Earl RA, Ellis JL, Garvey DS, Janero DR, Letts LG, Martino AM, Murty MG, Richardson SK, Schroeder JD, Shumway MJ, Tam SW, Trocha AM, Young DV.
    J Med Chem; 2004 Apr 22; 47(9):2180-93. PubMed ID: 15084117
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  • 34. Pharmacological evaluation and docking studies of α,β-unsaturated carbonyl based synthetic compounds as inhibitors of secretory phospholipase A₂, cyclooxygenases, lipoxygenase and proinflammatory cytokines.
    Bukhari SN, Lauro G, Jantan I, Bifulco G, Amjad MW.
    Bioorg Med Chem; 2014 Aug 01; 22(15):4151-61. PubMed ID: 24938495
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  • 35. Synthesis of 4,5-diaryl-1H-pyrazole-3-ol derivatives as potential COX-2 inhibitors.
    Patel MV, Bell R, Majest S, Henry R, Kolasa T.
    J Org Chem; 2004 Oct 15; 69(21):7058-65. PubMed ID: 15471453
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  • 36. Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core.
    Sisa M, Dvorakova M, Temml V, Jarosova V, Vanek T, Landa P.
    Eur J Med Chem; 2020 Oct 15; 204():112620. PubMed ID: 32738413
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  • 37. 2-hydroxymethyl-4-[5-(4-methoxyphenyl)-3-trifluoromethyl-1H-1-pyrazolyl]-1-benzenesulfonamide (DRF-4367): an orally active COX-2 inhibitor identified through pharmacophoric modulation.
    Singh SK, Vobbalareddy S, Kalleda SR, Rajjak SA, Casturi SR, Datla SR, Mamidi RN, Mullangi R, Bhamidipati R, Ramanujam R, Akella V, Yeleswarapu KR.
    Org Biomol Chem; 2004 Sep 07; 2(17):2442-50. PubMed ID: 15326524
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  • 38. Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents.
    Özadalı K, Özkanlı F, Jain S, Rao PP, Velázquez-Martínez CA.
    Bioorg Med Chem; 2012 May 01; 20(9):2912-22. PubMed ID: 22475926
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  • 39. Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4-formation.
    Schühly W, Hüfner A, Pferschy-Wenzig EM, Prettner E, Adams M, Bodensieck A, Kunert O, Oluwemimo A, Haslinger E, Bauer R.
    Bioorg Med Chem; 2009 Jul 01; 17(13):4459-65. PubMed ID: 19481465
    [Abstract] [Full Text] [Related]

  • 40. Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase.
    Shabaan MA, Kamal AM, Faggal SI, Elsahar AE, Mohamed KO.
    Arch Pharm (Weinheim); 2020 Apr 01; 353(4):e1900308. PubMed ID: 32031284
    [Abstract] [Full Text] [Related]

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