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Journal Abstract Search

172 related items for PubMed ID: 15653354

  • 1. N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists.
    Marchais-Oberwinkler S, Nowicki B, Pike VW, Halldin C, Sandell J, Chou YH, Gulyas B, Brennum LT, Farde L, Wikström HV.
    Bioorg Med Chem; 2005 Feb 01; 13(3):883-93. PubMed ID: 15653354
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  • 2. The pyridinyl-6 position of WAY-100635 as a site for radiofluorination--effect on 5-HT1A receptor radioligand behavior in vivo.
    McCarron JA, Pike VW, Halldin C, Sandell J, Sóvágó J, Gulyas B, Cselényi Z, Wikström HV, Marchais-Oberwinkler S, Nowicki B, Dollé F, Farde L.
    Mol Imaging Biol; 2004 Feb 01; 6(1):17-26. PubMed ID: 15018825
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  • 5. WAY-100635 antagonist-induced plasticity of 5-HT receptors: regulatory differences between a stable cell line and an in vivo native system.
    Khawaja XZ, Smith DL, Nawoschik SP, Zhang J, Dunlop J, Dilks DW, Olsen M, Schechter LE.
    J Neurochem; 2006 Jul 01; 98(1):134-45. PubMed ID: 16805803
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  • 6. Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635--explanation of high signal contrast in PET and an aid to biomathematical modelling.
    Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Farde L, Ginovart N, Luthra SK, Gunn RN, Bench CJ, Sargent PA, Grasby PM.
    Nucl Med Biol; 1998 Apr 01; 25(3):215-23. PubMed ID: 9620626
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  • 7. [carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT1A receptors in vitro and in vivo.
    Pike VW, Halldin C, McCarron JA, Lundkvist C, Hirani E, Olsson H, Hume SP, Karlsson P, Osman S, Swahn CG, Hall H, Wikström H, Mensonidas M, Poole KG, Farde L.
    Eur J Nucl Med; 1998 Apr 01; 25(4):338-46. PubMed ID: 9553162
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  • 8. The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain.
    Andrée B, Halldin C, Pike VW, Gunn RN, Olsson H, Farde L.
    J Nucl Med; 2002 Mar 01; 43(3):292-303. PubMed ID: 11884487
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  • 9. Synthesis and in vivo validation of [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione: a novel 5-HT1A receptor agonist positron emission tomography ligand.
    Kumar JS, Majo VJ, Hsiung SC, Millak MS, Liu KP, Tamir H, Prabhakaran J, Simpson NR, Van Heertum RL, Mann JJ, Parsey RV.
    J Med Chem; 2006 Jan 12; 49(1):125-34. PubMed ID: 16392798
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  • 11. Development of fluorine-18-labeled 5-HT1A antagonists.
    Lang L, Jagoda E, Schmall B, Vuong BK, Adams HR, Nelson DL, Carson RE, Eckelman WC.
    J Med Chem; 1999 May 06; 42(9):1576-86. PubMed ID: 10229627
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  • 12. Characterization of the radioactive metabolites of the 5-HT1A receptor radioligand, [O-methyl-11C]WAY-100635, in monkey and human plasma by HPLC: comparison of the behaviour of an identified radioactive metabolite with parent radioligand in monkey using PET.
    Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Ginovart N, Luthra SK, Bench CJ, Grasby PM, Wikström H, Barf T, Cliffe IA, Fletcher A, Farde L.
    Nucl Med Biol; 1996 Jul 06; 23(5):627-34. PubMed ID: 8905828
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  • 15. Two C-methyl derivatives of [11C]WAY-100635--effects of an amido alpha-methyl group on metabolism and brain 5-HT1A receptor radioligand behavior in monkey.
    McCarron JA, Marchais-Oberwinkler S, Pike VW, Tarkiainen J, Halldin C, Sóvagó J, Gulyas B, Wikström HV, Farde L.
    Mol Imaging Biol; 2005 Jul 06; 7(3):209-19. PubMed ID: 15912425
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  • 17. Synthesis and initial evaluation of [11C](R)-RWAY in monkey-a new, simply labeled antagonist radioligand for imaging brain 5-HT1A receptors with PET.
    McCarron JA, Zoghbi SS, Shetty HU, Vermeulen ES, Wikström HV, Ichise M, Yasuno F, Halldin C, Innis RB, Pike VW.
    Eur J Nucl Med Mol Imaging; 2007 Oct 06; 34(10):1670-82. PubMed ID: 17579853
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  • 18. Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT(1A) receptor.
    Perrone R, Berardi F, Colabufo NA, Lacivita E, Larizza C, Leopoldo M, Tortorella V.
    J Pharm Pharmacol; 2005 Oct 06; 57(10):1319-27. PubMed ID: 16259761
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  • 19. Differential effects of the 5-hydroxytryptamine (5-HT)1A receptor inverse agonists Rec 27/0224 and Rec 27/0074 on electrophysiological responses to 5-HT1A receptor activation in rat dorsal raphe nucleus and hippocampus in vitro.
    Corradetti R, Mlinar B, Falsini C, Pugliese AM, Cilia A, Destefani C, Testa R.
    J Pharmacol Exp Ther; 2005 Oct 06; 315(1):109-17. PubMed ID: 15951403
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  • 20. Comparison of 4 radiolabeled antagonists for serotonin 5-HT(7) receptor neuroimaging: toward the first PET radiotracer.
    Lemoine L, Andries J, Le Bars D, Billard T, Zimmer L.
    J Nucl Med; 2011 Nov 06; 52(11):1811-8. PubMed ID: 21990574
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