These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

195 related items for PubMed ID: 15662045

  • 1. Subtype-specific affinity for corticosterone of rat organic cation transporters rOCT1 and rOCT2 depends on three amino acids within the substrate binding region.
    Gorboulev V, Shatskaya N, Volk C, Koepsell H.
    Mol Pharmacol; 2005 May; 67(5):1612-9. PubMed ID: 15662045
    [Abstract] [Full Text] [Related]

  • 2. Five amino acids in the innermost cavity of the substrate binding cleft of organic cation transporter 1 interact with extracellular and intracellular corticosterone.
    Volk C, Gorboulev V, Kotzsch A, Müller TD, Koepsell H.
    Mol Pharmacol; 2009 Aug; 76(2):275-89. PubMed ID: 19435783
    [Abstract] [Full Text] [Related]

  • 3. Amino acids critical for substrate affinity of rat organic cation transporter 1 line the substrate binding region in a model derived from the tertiary structure of lactose permease.
    Popp C, Gorboulev V, Müller TD, Gorbunov D, Shatskaya N, Koepsell H.
    Mol Pharmacol; 2005 May; 67(5):1600-11. PubMed ID: 15662044
    [Abstract] [Full Text] [Related]

  • 4. Identification of cysteines in rat organic cation transporters rOCT1 (C322, C451) and rOCT2 (C451) critical for transport activity and substrate affinity.
    Sturm A, Gorboulev V, Gorbunov D, Keller T, Volk C, Schmitt BM, Schlachtbauer P, Ciarimboli G, Koepsell H.
    Am J Physiol Renal Physiol; 2007 Sep; 293(3):F767-79. PubMed ID: 17567940
    [Abstract] [Full Text] [Related]

  • 5. Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.
    Ishiguro N, Saito A, Yokoyama K, Morikawa M, Igarashi T, Tamai I.
    Drug Metab Dispos; 2005 Apr; 33(4):495-9. PubMed ID: 15640376
    [Abstract] [Full Text] [Related]

  • 6. Different affinities of inhibitors to the outwardly and inwardly directed substrate binding site of organic cation transporter 2.
    Volk C, Gorboulev V, Budiman T, Nagel G, Koepsell H.
    Mol Pharmacol; 2003 Nov; 64(5):1037-47. PubMed ID: 14573752
    [Abstract] [Full Text] [Related]

  • 7. The organic cation transporters rOCT1 and hOCT2 are inhibited by cGMP.
    Schlatter E, Mönnich V, Cetinkaya I, Mehrens T, Ciarimboli G, Hirsch JR, Popp C, Koepsell H.
    J Membr Biol; 2002 Oct 01; 189(3):237-44. PubMed ID: 12395288
    [Abstract] [Full Text] [Related]

  • 8. Reduced expression of organic cation transporters rOCT1 and rOCT2 in experimental diabetes.
    Grover B, Buckley D, Buckley AR, Cacini W.
    J Pharmacol Exp Ther; 2004 Mar 01; 308(3):949-56. PubMed ID: 14718608
    [Abstract] [Full Text] [Related]

  • 9. High-affinity cation binding to organic cation transporter 1 induces movement of helix 11 and blocks transport after mutations in a modeled interaction domain between two helices.
    Gorbunov D, Gorboulev V, Shatskaya N, Mueller T, Bamberg E, Friedrich T, Koepsell H.
    Mol Pharmacol; 2008 Jan 01; 73(1):50-61. PubMed ID: 17940192
    [Abstract] [Full Text] [Related]

  • 10. The cation transporters rOCT1 and rOCT2 interact with bicarbonate but play only a minor role for amantadine uptake into rat renal proximal tubules.
    Goralski KB, Lou G, Prowse MT, Gorboulev V, Volk C, Koepsell H, Sitar DS.
    J Pharmacol Exp Ther; 2002 Dec 01; 303(3):959-68. PubMed ID: 12438515
    [Abstract] [Full Text] [Related]

  • 11. Mutation of amino acid 475 of rat organic cation transporter 2 (rOCT2) impairs organic cation transport.
    Bahn A, Hagos Y, Rudolph T, Burckhardt G.
    Biochimie; 2004 Feb 01; 86(2):133-6. PubMed ID: 15016452
    [Abstract] [Full Text] [Related]

  • 12. Purification and functional reconstitution of the rat organic cation transporter OCT1.
    Keller T, Elfeber M, Gorboulev V, Reiländer H, Koepsell H.
    Biochemistry; 2005 Sep 13; 44(36):12253-63. PubMed ID: 16142924
    [Abstract] [Full Text] [Related]

  • 13. Charge-to-substrate ratio during organic cation uptake by rat OCT2 is voltage dependent and altered by exchange of glutamate 448 with glutamine.
    Schmitt BM, Gorbunov D, Schlachtbauer P, Egenberger B, Gorboulev V, Wischmeyer E, Müller T, Koepsell H.
    Am J Physiol Renal Physiol; 2009 Apr 13; 296(4):F709-22. PubMed ID: 19211691
    [Abstract] [Full Text] [Related]

  • 14. Substrate- and cell contact-dependent inhibitor affinity of human organic cation transporter 2: studies with two classical organic cation substrates and the novel substrate cd2+.
    Thévenod F, Ciarimboli G, Leistner M, Wolff NA, Lee WK, Schatz I, Keller T, Al-Monajjed R, Gorboulev V, Koepsell H.
    Mol Pharm; 2013 Aug 05; 10(8):3045-56. PubMed ID: 23763587
    [Abstract] [Full Text] [Related]

  • 15. Nitric oxide-induced regulation of renal organic cation transport after renal ischemia-reperfusion injury.
    Schneider R, Meusel M, Betz B, Kersten M, Möller-Ehrlich K, Wanner C, Koepsell H, Sauvant C.
    Am J Physiol Renal Physiol; 2011 Nov 05; 301(5):F997-F1004. PubMed ID: 21835768
    [Abstract] [Full Text] [Related]

  • 16. Assay Conditions Influence Affinities of Rat Organic Cation Transporter 1: Analysis of Mutagenesis in the Modeled Outward-Facing Cleft by Measuring Effects of Substrates and Inhibitors on Initial Uptake.
    Gorboulev V, Rehman S, Albert CM, Roth U, Meyer MJ, Tzvetkov MV, Mueller TD, Koepsell H.
    Mol Pharmacol; 2018 Apr 05; 93(4):402-415. PubMed ID: 29339398
    [Abstract] [Full Text] [Related]

  • 17. Comparison of the kinetic characteristics of inhibitory effects exerted by biguanides and H2-blockers on human and rat organic cation transporter-mediated transport: Insight into the development of drug candidates.
    Umehara KI, Iwatsubo T, Noguchi K, Kamimura H.
    Xenobiotica; 2007 Jun 05; 37(6):618-34. PubMed ID: 17614008
    [Abstract] [Full Text] [Related]

  • 18. Organic cation transporter-mediated renal secretion of ipratropium and tiotropium in rats and humans.
    Nakanishi T, Haruta T, Shirasaka Y, Tamai I.
    Drug Metab Dispos; 2011 Jan 05; 39(1):117-22. PubMed ID: 20962061
    [Abstract] [Full Text] [Related]

  • 19. Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1.
    Arndt P, Volk C, Gorboulev V, Budiman T, Popp C, Ulzheimer-Teuber I, Akhoundova A, Koppatz S, Bamberg E, Nagel G, Koepsell H.
    Am J Physiol Renal Physiol; 2001 Sep 05; 281(3):F454-68. PubMed ID: 11502595
    [Abstract] [Full Text] [Related]

  • 20. The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerization.
    Keller T, Egenberger B, Gorboulev V, Bernhard F, Uzelac Z, Gorbunov D, Wirth C, Koppatz S, Dötsch V, Hunte C, Sitte HH, Koepsell H.
    J Biol Chem; 2011 Oct 28; 286(43):37874-86. PubMed ID: 21896487
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 10.