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Journal Abstract Search

235 related items for PubMed ID: 15664853

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  • 2. Discovery of 2,3,5-trisubstituted pyridine derivatives as potent Akt1 and Akt2 dual inhibitors.
    Zhao Z, Leister WH, Robinson RG, Barnett SF, Defeo-Jones D, Jones RE, Hartman GD, Huff JR, Huber HE, Duggan ME, Lindsley CW.
    Bioorg Med Chem Lett; 2005 Feb 15; 15(4):905-9. PubMed ID: 15686884
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  • 4. Development of potent, allosteric dual Akt1 and Akt2 inhibitors with improved physical properties and cell activity.
    Zhao Z, Robinson RG, Barnett SF, Defeo-Jones D, Jones RE, Hartman GD, Huber HE, Duggan ME, Lindsley CW.
    Bioorg Med Chem Lett; 2008 Jan 01; 18(1):49-53. PubMed ID: 18054229
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  • 12. The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.
    Kandel ES, Hay N.
    Exp Cell Res; 1999 Nov 25; 253(1):210-29. PubMed ID: 10579924
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  • 13. Coadministration of histone deacetylase inhibitors and perifosine synergistically induces apoptosis in human leukemia cells through Akt and ERK1/2 inactivation and the generation of ceramide and reactive oxygen species.
    Rahmani M, Reese E, Dai Y, Bauer C, Payne SG, Dent P, Spiegel S, Grant S.
    Cancer Res; 2005 Mar 15; 65(6):2422-32. PubMed ID: 15781658
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  • 14. Pseudosubstrate peptides inhibit Akt and induce cell growth inhibition.
    Luo Y, Smith RA, Guan R, Liu X, Klinghofer V, Shen J, Hutchins C, Richardson P, Holzman T, Rosenberg SH, Giranda VL.
    Biochemistry; 2004 Feb 10; 43(5):1254-63. PubMed ID: 14756561
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  • 17. Novel 2'-substituted, 3'-deoxy-phosphatidyl-myo-inositol analogues reduce drug resistance in human leukaemia cell lines with an activated phosphoinositide 3-kinase/Akt pathway.
    Tabellini G, Tazzari PL, Bortul R, Billi AM, Conte R, Manzoli L, Cocco L, Martelli AM.
    Br J Haematol; 2004 Aug 10; 126(4):574-82. PubMed ID: 15287952
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  • 20. Hepatocyte growth factor enhances protein phosphatase Cdc25A inhibitor compound 5-induced hepatoma cell growth inhibition via Akt-mediated MAPK pathway.
    Wang Z, Wang M, Carr BI.
    J Cell Physiol; 2005 Jun 10; 203(3):510-9. PubMed ID: 15534860
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