These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Mutational analysis of extracellular cysteine residues of rat secretin receptor shows that disulfide bridges are essential for receptor function. Vilardaga JP, Di Paolo E, Bialek C, De Neef P, Waelbroeck M, Bollen A, Robberecht P. Eur J Biochem; 1997 May 15; 246(1):173-80. PubMed ID: 9210480 [Abstract] [Full Text] [Related]
5. Functional importance of a structurally distinct homodimeric complex of the family B G protein-coupled secretin receptor. Gao F, Harikumar KG, Dong M, Lam PC, Sexton PM, Christopoulos A, Bordner A, Abagyan R, Miller LJ. Mol Pharmacol; 2009 Aug 15; 76(2):264-74. PubMed ID: 19429716 [Abstract] [Full Text] [Related]
6. Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor. Dong M, Lam PC, Orry A, Sexton PM, Christopoulos A, Abagyan R, Miller LJ. J Biol Chem; 2016 Mar 04; 291(10):5172-84. PubMed ID: 26740626 [Abstract] [Full Text] [Related]
7. An intramolecular disulfide bond between conserved extracellular cysteines in the gonadotropin-releasing hormone receptor is essential for binding and activation. Cook JV, Eidne KA. Endocrinology; 1997 Jul 04; 138(7):2800-6. PubMed ID: 9202220 [Abstract] [Full Text] [Related]
11. Structural basis of natural ligand binding and activation of the Class II G-protein-coupled secretin receptor. Miller LJ, Dong M, Harikumar KG, Gao F. Biochem Soc Trans; 2007 Aug 04; 35(Pt 4):709-12. PubMed ID: 17635130 [Abstract] [Full Text] [Related]
12. Spatial approximation between secretin residue five and the third extracellular loop of its receptor provides new insight into the molecular basis of natural agonist binding. Dong M, Lam PC, Pinon DI, Sexton PM, Abagyan R, Miller LJ. Mol Pharmacol; 2008 Aug 04; 74(2):413-22. PubMed ID: 18467541 [Abstract] [Full Text] [Related]
13. Analysis of parathyroid hormone (PTH)/secretin receptor chimeras differentiates the role of functional domains in the pth/ pth-related peptide (PTHrP) receptor on hormone binding and receptor activation. Vilardaga JP, Lin I, Nissenson RA. Mol Endocrinol; 2001 Jul 04; 15(7):1186-99. PubMed ID: 11435617 [Abstract] [Full Text] [Related]
14. Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints. Dong M, Pinon DI, Bordner AJ, Miller LJ. Bioorg Med Chem Lett; 2010 Oct 15; 20(20):6040-4. PubMed ID: 20813522 [Abstract] [Full Text] [Related]
15. Role of N-linked glycosylation on the function and expression of the human secretin receptor. Pang RT, Ng SS, Cheng CH, Holtmann MH, Miller LJ, Chow BK. Endocrinology; 1999 Nov 15; 140(11):5102-11. PubMed ID: 10537138 [Abstract] [Full Text] [Related]
16. Fluorescence resonance energy transfer analysis of secretin docking to its receptor: mapping distances between residues distributed throughout the ligand pharmacophore and distinct receptor residues. Harikumar KG, Lam PC, Dong M, Sexton PM, Abagyan R, Miller LJ. J Biol Chem; 2007 Nov 09; 282(45):32834-43. PubMed ID: 17827151 [Abstract] [Full Text] [Related]
19. Role of charged amino acids conserved in the vasoactive intestinal polypeptide/secretin family of receptors on the secretin receptor functionality. Di Paolo E, Vilardaga JP, Petry H, Moguilevsky N, Bollen A, Robberecht P, Waelbroeck M. Peptides; 1999 Nov 09; 20(10):1187-93. PubMed ID: 10573290 [Abstract] [Full Text] [Related]