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Journal Abstract Search

117 related items for PubMed ID: 15665137

  • 21. Structure-activity study with bioreductive benzoquinone alkylating agents: effects on DT-diaphorase-mediated DNA crosslink and strand break formation in relation to mechanisms of cytotoxicity.
    Fourie J, Guziec F, Guziec L, Monterrosa C, Fiterman DJ, Begleiter A.
    Cancer Chemother Pharmacol; 2004 Mar; 53(3):191-203. PubMed ID: 14614574
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  • 22. The abnormal cytotoxicities of 2,5-diaziridinyl-1,4-benzoquinone-3-phenyl esters.
    Di Francesco AM, Hargreaves RH, Wallace TW, Mayalarp SP, Hazrati A, Hartley JA, Butler J.
    Anticancer Drug Des; 2000 Oct; 15(5):347-59. PubMed ID: 11354311
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  • 23. Pharmacological properties of a new aziridinylbenzoquinone, RH1 (2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone), in mice.
    Loadman PM, Phillips RM, Lim LE, Bibby MC.
    Biochem Pharmacol; 2000 Apr 01; 59(7):831-7. PubMed ID: 10718341
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  • 24. Development of indolequinone mechanism-based inhibitors of NAD(P)H:quinone oxidoreductase 1 (NQO1): NQO1 inhibition and growth inhibitory activity in human pancreatic MIA PaCa-2 cancer cells.
    Reigan P, Colucci MA, Siegel D, Chilloux A, Moody CJ, Ross D.
    Biochemistry; 2007 May 22; 46(20):5941-50. PubMed ID: 17455910
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  • 25. The bioreductive agent RH1 and gamma-irradiation both cause G2/M cell cycle phase arrest and polyploidy in a p53-mutated human breast cancer cell line.
    Kim JY, Kim CH, Stratford IJ, Patterson AV, Hendry JH.
    Int J Radiat Oncol Biol Phys; 2004 Feb 01; 58(2):376-85. PubMed ID: 14751506
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  • 26. Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines.
    Beall HD, Murphy AM, Siegel D, Hargreaves RH, Butler J, Ross D.
    Mol Pharmacol; 1995 Sep 01; 48(3):499-504. PubMed ID: 7565631
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  • 27. p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin.
    Huang S, Liu LN, Hosoi H, Dilling MB, Shikata T, Houghton PJ.
    Cancer Res; 2001 Apr 15; 61(8):3373-81. PubMed ID: 11309295
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  • 32. The novel sequence-specific DNA cross-linking agent SJG-136 (NSC 694501) has potent and selective in vitro cytotoxicity in human B-cell chronic lymphocytic leukemia cells with evidence of a p53-independent mechanism of cell kill.
    Pepper CJ, Hambly RM, Fegan CD, Delavault P, Thurston DE.
    Cancer Res; 2004 Sep 15; 64(18):6750-5. PubMed ID: 15374993
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  • 33. Constitutive expression of human Bcl-2 modulates nitrogen mustard and camptothecin induced apoptosis.
    Walton MI, Whysong D, O'Connor PM, Hockenbery D, Korsmeyer SJ, Kohn KW.
    Cancer Res; 1993 Apr 15; 53(8):1853-61. PubMed ID: 8467505
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  • 34. Activity of quinone alkylating agents in quinone-resistant cells.
    Begleiter A, Leith MK.
    Cancer Res; 1990 May 15; 50(10):2872-6. PubMed ID: 1692249
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  • 36. Induction of apoptosis and cell cycle-specific change in expression of p53 in normal lymphocytes and MOLT-4 leukemic cells by nitrogen mustard.
    Bhatia U, Danishefsky K, Traganos F, Darzynkiewicz Z.
    Clin Cancer Res; 1995 Aug 15; 1(8):873-80. PubMed ID: 9816057
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  • 37. DNA strand scission and cross-linking by diaziridinylbenzoquinone (diaziquone) in human cells and relation to cell killing.
    Szmigiero L, Erickson LC, Ewig RA, Kohn KW.
    Cancer Res; 1984 Oct 15; 44(10):4447-52. PubMed ID: 6467204
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  • 39. Overexpression of NQO1 protects human SK-N-MC neuroblastoma cells against dopamine-induced cell death.
    Zafar KS, Inayat-Hussain SH, Siegel D, Bao A, Shieh B, Ross D.
    Toxicol Lett; 2006 Oct 25; 166(3):261-7. PubMed ID: 16978807
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  • 40. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D, Gibson NW, Preusch PC, Ross D.
    Cancer Res; 1990 Nov 15; 50(22):7293-300. PubMed ID: 2121335
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