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328 related items for PubMed ID: 15665520

  • 1. VEGF production by primary human renal proximal tubular cells: requirement of HIF-1, PI3-kinase and MAPKK-1 signaling.
    Hellwig-Bürgel T, Stiehl DP, Katschinski DM, Marxsen J, Kreft B, Jelkmann W.
    Cell Physiol Biochem; 2005; 15(1-4):99-108. PubMed ID: 15665520
    [Abstract] [Full Text] [Related]

  • 2. Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway.
    Blancher C, Moore JW, Robertson N, Harris AL.
    Cancer Res; 2001 Oct 01; 61(19):7349-55. PubMed ID: 11585776
    [Abstract] [Full Text] [Related]

  • 3. Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.
    Mabjeesh NJ, Willard MT, Frederickson CE, Zhong H, Simons JW.
    Clin Cancer Res; 2003 Jul 01; 9(7):2416-25. PubMed ID: 12855613
    [Abstract] [Full Text] [Related]

  • 4. In vitro study of HIF-1 activation and VEGF release by bFGF in the T47D breast cancer cell line under normoxic conditions: involvement of PI-3K/Akt and MEK1/ERK pathways.
    Shi YH, Wang YX, Bingle L, Gong LH, Heng WJ, Li Y, Fang WG.
    J Pathol; 2005 Mar 01; 205(4):530-6. PubMed ID: 15714461
    [Abstract] [Full Text] [Related]

  • 5. Hypoxia and interleukin-1beta stimulate vascular endothelial growth factor production in human proximal tubular cells.
    El Awad B, Kreft B, Wolber EM, Hellwig-Bürgel T, Metzen E, Fandrey J, Jelkmann W.
    Kidney Int; 2000 Jul 01; 58(1):43-50. PubMed ID: 10886548
    [Abstract] [Full Text] [Related]

  • 6. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
    Treins C, Giorgetti-Peraldi S, Murdaca J, Semenza GL, Van Obberghen E.
    J Biol Chem; 2002 Aug 02; 277(31):27975-81. PubMed ID: 12032158
    [Abstract] [Full Text] [Related]

  • 7. Morphine inhibits VEGF expression in myocardial ischemia.
    Roy S, Balasubramanian S, Wang J, Chandrashekhar Y, Charboneau R, Barke R.
    Surgery; 2003 Aug 02; 134(2):336-44. PubMed ID: 12947338
    [Abstract] [Full Text] [Related]

  • 8. Arsenite induces HIF-1alpha and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells.
    Gao N, Shen L, Zhang Z, Leonard SS, He H, Zhang XG, Shi X, Jiang BH.
    Mol Cell Biochem; 2004 Jan 02; 255(1-2):33-45. PubMed ID: 14971644
    [Abstract] [Full Text] [Related]

  • 9. 4-Hydroxy estradiol but not 2-hydroxy estradiol induces expression of hypoxia-inducible factor 1alpha and vascular endothelial growth factor A through phosphatidylinositol 3-kinase/Akt/FRAP pathway in OVCAR-3 and A2780-CP70 human ovarian carcinoma cells.
    Gao N, Nester RA, Sarkar MA.
    Toxicol Appl Pharmacol; 2004 Apr 01; 196(1):124-35. PubMed ID: 15050414
    [Abstract] [Full Text] [Related]

  • 10. HER2 (neu) signaling increases the rate of hypoxia-inducible factor 1alpha (HIF-1alpha) synthesis: novel mechanism for HIF-1-mediated vascular endothelial growth factor expression.
    Laughner E, Taghavi P, Chiles K, Mahon PC, Semenza GL.
    Mol Cell Biol; 2001 Jun 01; 21(12):3995-4004. PubMed ID: 11359907
    [Abstract] [Full Text] [Related]

  • 11. Regulation of hypoxia-inducible factor-1alpha protein level during hypoxic conditions by the phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3beta pathway in HepG2 cells.
    Mottet D, Dumont V, Deccache Y, Demazy C, Ninane N, Raes M, Michiels C.
    J Biol Chem; 2003 Aug 15; 278(33):31277-85. PubMed ID: 12764143
    [Abstract] [Full Text] [Related]

  • 12. Phosphatidylinositol 3-kinase signaling controls levels of hypoxia-inducible factor 1.
    Jiang BH, Jiang G, Zheng JZ, Lu Z, Hunter T, Vogt PK.
    Cell Growth Differ; 2001 Jul 15; 12(7):363-9. PubMed ID: 11457733
    [Abstract] [Full Text] [Related]

  • 13. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics.
    Zhong H, Chiles K, Feldser D, Laughner E, Hanrahan C, Georgescu MM, Simons JW, Semenza GL.
    Cancer Res; 2000 Mar 15; 60(6):1541-5. PubMed ID: 10749120
    [Abstract] [Full Text] [Related]

  • 14. Celecoxib Down-Regulates the Hypoxia-Induced Expression of HIF-1α and VEGF Through the PI3K/AKT Pathway in Retinal Pigment Epithelial Cells.
    Sun YZ, Cai N, Liu NN.
    Cell Physiol Biochem; 2017 Mar 15; 44(4):1640-1650. PubMed ID: 29216640
    [Abstract] [Full Text] [Related]

  • 15. Induction of hypoxia-inducible-factor 1 by nitric oxide is mediated via the PI 3K pathway.
    Sandau KB, Faus HG, Brüne B.
    Biochem Biophys Res Commun; 2000 Nov 11; 278(1):263-7. PubMed ID: 11071882
    [Abstract] [Full Text] [Related]

  • 16. [Hypoxia induced HIF-1 accumulation and VEGF expression in gastric epithelial mucosa cell: involvement of ERK1/2 and PI3K/Akt].
    Liu L, Ning X, Han S, Zhang H, Sun L, Shi Y, Sun S, Guo C, Yin F, Qiao T, Wu K, Fan D.
    Mol Biol (Mosk); 2008 Nov 11; 42(3):459-69. PubMed ID: 18702304
    [Abstract] [Full Text] [Related]

  • 17. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
    Zhou J, Schmid T, Frank R, Brüne B.
    J Biol Chem; 2004 Apr 02; 279(14):13506-13. PubMed ID: 14726529
    [Abstract] [Full Text] [Related]

  • 18. Evidence for a role of p38 kinase in hypoxia-inducible factor 1-independent induction of vascular endothelial growth factor expression by sodium arsenite.
    Duyndam MC, Hulscher ST, van der Wall E, Pinedo HM, Boven E.
    J Biol Chem; 2003 Feb 28; 278(9):6885-95. PubMed ID: 12482858
    [Abstract] [Full Text] [Related]

  • 19. Mitogen-activated protein kinase kinase inhibitor PD98059 blocks the trans-activation but not the stabilization or DNA binding ability of hypoxia-inducible factor-1alpha.
    Hur E, Chang KY, Lee E, Lee SK, Park H.
    Mol Pharmacol; 2001 May 28; 59(5):1216-24. PubMed ID: 11306706
    [Abstract] [Full Text] [Related]

  • 20. Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.
    Alvarez-Tejado M, Alfranca A, Aragonés J, Vara A, Landázuri MO, del Peso L.
    J Biol Chem; 2002 Apr 19; 277(16):13508-17. PubMed ID: 11815624
    [Abstract] [Full Text] [Related]

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