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510 related items for PubMed ID: 15665818

  • 1. Akt inhibition upregulates FasL, downregulates c-FLIPs and induces caspase-8-dependent cell death in Jurkat T lymphocytes.
    Uriarte SM, Joshi-Barve S, Song Z, Sahoo R, Gobejishvili L, Jala VR, Haribabu B, McClain C, Barve S.
    Cell Death Differ; 2005 Mar; 12(3):233-42. PubMed ID: 15665818
    [Abstract] [Full Text] [Related]

  • 2. Fas-associated death domain protein (FADD) and caspase-8 mediate up-regulation of c-Fos by Fas ligand and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) via a FLICE inhibitory protein (FLIP)-regulated pathway.
    Siegmund D, Mauri D, Peters N, Juo P, Thome M, Reichwein M, Blenis J, Scheurich P, Tschopp J, Wajant H.
    J Biol Chem; 2001 Aug 31; 276(35):32585-90. PubMed ID: 11384965
    [Abstract] [Full Text] [Related]

  • 3. FADD deficiency sensitises Jurkat T cells to TNF-alpha-dependent necrosis during activation-induced cell death.
    Lawrence CP, Chow SC.
    FEBS Lett; 2005 Nov 21; 579(28):6465-72. PubMed ID: 16289096
    [Abstract] [Full Text] [Related]

  • 4. Mitogen-activated protein kinase kinase antagonized fas-associated death domain protein-mediated apoptosis by induced FLICE-inhibitory protein expression.
    Yeh JH, Hsu SC, Han SH, Lai MZ.
    J Exp Med; 1998 Nov 16; 188(10):1795-802. PubMed ID: 9815257
    [Abstract] [Full Text] [Related]

  • 5. Constitutive caspase activation and impaired death-inducing signaling complex formation in CD95-resistant, long-term activated, antigen-specific T cells.
    Strauss G, Knape I, Melzner I, Debatin KM.
    J Immunol; 2003 Aug 01; 171(3):1172-82. PubMed ID: 12874203
    [Abstract] [Full Text] [Related]

  • 6. MAPK/ERK signaling in activated T cells inhibits CD95/Fas-mediated apoptosis downstream of DISC assembly.
    Holmström TH, Schmitz I, Söderström TS, Poukkula M, Johnson VL, Chow SC, Krammer PH, Eriksson JE.
    EMBO J; 2000 Oct 16; 19(20):5418-28. PubMed ID: 11032809
    [Abstract] [Full Text] [Related]

  • 7. NFkappaB activation by Fas is mediated through FADD, caspase-8, and RIP and is inhibited by FLIP.
    Kreuz S, Siegmund D, Rumpf JJ, Samel D, Leverkus M, Janssen O, Häcker G, Dittrich-Breiholz O, Kracht M, Scheurich P, Wajant H.
    J Cell Biol; 2004 Aug 02; 166(3):369-80. PubMed ID: 15289496
    [Abstract] [Full Text] [Related]

  • 8. Intracellular mechanisms mediating tocotrienol-induced apoptosis in neoplastic mammary epithelial cells.
    Sylvester PW, Shah S.
    Asia Pac J Clin Nutr; 2005 Aug 02; 14(4):366-73. PubMed ID: 16326643
    [Abstract] [Full Text] [Related]

  • 9. Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells.
    Panka DJ, Mano T, Suhara T, Walsh K, Mier JW.
    J Biol Chem; 2001 Mar 09; 276(10):6893-6. PubMed ID: 11145953
    [Abstract] [Full Text] [Related]

  • 10. Mitogen-activated protein kinase/extracellular signal-regulated kinase signaling in activated T cells abrogates TRAIL-induced apoptosis upstream of the mitochondrial amplification loop and caspase-8.
    Söderström TS, Poukkula M, Holmström TH, Heiskanen KM, Eriksson JE.
    J Immunol; 2002 Sep 15; 169(6):2851-60. PubMed ID: 12218097
    [Abstract] [Full Text] [Related]

  • 11. Phosphatidylinositol 3-kinase/Akt positively regulates Fas (CD95)-mediated apoptosis in epidermal Cl41 cells.
    Lu B, Wang L, Stehlik C, Medan D, Huang C, Hu S, Chen F, Shi X, Rojanasakul Y.
    J Immunol; 2006 Jun 01; 176(11):6785-93. PubMed ID: 16709838
    [Abstract] [Full Text] [Related]

  • 12. Short-term delay of Fas-stimulated apoptosis by GM-CSF as a result of temporary suppression of FADD recruitment in neutrophils: evidence implicating phosphatidylinositol 3-kinase and MEK1-ERK1/2 pathways downstream of classical protein kinase C.
    Kotone-Miyahara Y, Yamashita K, Lee KK, Yonehara S, Uchiyama T, Sasada M, Takahashi A.
    J Leukoc Biol; 2004 Nov 01; 76(5):1047-56. PubMed ID: 15328334
    [Abstract] [Full Text] [Related]

  • 13. Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer.
    Chen X, Thakkar H, Tyan F, Gim S, Robinson H, Lee C, Pandey SK, Nwokorie C, Onwudiwe N, Srivastava RK.
    Oncogene; 2001 Sep 20; 20(42):6073-83. PubMed ID: 11593415
    [Abstract] [Full Text] [Related]

  • 14. Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation.
    Suhara T, Kim HS, Kirshenbaum LA, Walsh K.
    Mol Cell Biol; 2002 Jan 20; 22(2):680-91. PubMed ID: 11756562
    [Abstract] [Full Text] [Related]

  • 15. Caspase-8 activation is necessary but not sufficient for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in the prostatic carcinoma cell line LNCaP.
    Rokhlin OW, Guseva NV, Tagiyev AF, Glover RA, Cohen MB.
    Prostate; 2002 Jun 01; 52(1):1-11. PubMed ID: 11992615
    [Abstract] [Full Text] [Related]

  • 16. Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways.
    Suliman A, Lam A, Datta R, Srivastava RK.
    Oncogene; 2001 Apr 19; 20(17):2122-33. PubMed ID: 11360196
    [Abstract] [Full Text] [Related]

  • 17. Downregulation of c-FLIP sensitizes DU145 prostate cancer cells to Fas-mediated apoptosis.
    Hyer ML, Sudarshan S, Kim Y, Reed JC, Dong JY, Schwartz DA, Norris JS.
    Cancer Biol Ther; 2002 Apr 19; 1(4):401-6. PubMed ID: 12432255
    [Abstract] [Full Text] [Related]

  • 18. Heat stress downregulates FLIP and sensitizes cells to Fas receptor-mediated apoptosis.
    Tran SE, Meinander A, Holmström TH, Rivero-Müller A, Heiskanen KM, Linnau EK, Courtney MJ, Mosser DD, Sistonen L, Eriksson JE.
    Cell Death Differ; 2003 Oct 19; 10(10):1137-47. PubMed ID: 14502237
    [Abstract] [Full Text] [Related]

  • 19. Tocotrienol-induced caspase-8 activation is unrelated to death receptor apoptotic signaling in neoplastic mammary epithelial cells.
    Shah S, Sylvester PW.
    Exp Biol Med (Maywood); 2004 Sep 19; 229(8):745-55. PubMed ID: 15337828
    [Abstract] [Full Text] [Related]

  • 20. p38-mediated regulation of an Fas-associated death domain protein-independent pathway leading to caspase-8 activation during TGFbeta-induced apoptosis in human Burkitt lymphoma B cells BL41.
    Schrantz N, Bourgeade MF, Mouhamad S, Leca G, Sharma S, Vazquez A.
    Mol Biol Cell; 2001 Oct 19; 12(10):3139-51. PubMed ID: 11598198
    [Abstract] [Full Text] [Related]

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