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480 related items for PubMed ID: 15668244

  • 1. Phosphodiesterase-5 inhibitor sildenafil preconditions adult cardiac myocytes against necrosis and apoptosis. Essential role of nitric oxide signaling.
    Das A, Xi L, Kukreja RC.
    J Biol Chem; 2005 Apr 01; 280(13):12944-55. PubMed ID: 15668244
    [Abstract] [Full Text] [Related]

  • 2. Phosphodiesterase-5 inhibition with sildenafil attenuates cardiomyocyte apoptosis and left ventricular dysfunction in a chronic model of doxorubicin cardiotoxicity.
    Fisher PW, Salloum F, Das A, Hyder H, Kukreja RC.
    Circulation; 2005 Apr 05; 111(13):1601-10. PubMed ID: 15811867
    [Abstract] [Full Text] [Related]

  • 3. ERK phosphorylation mediates sildenafil-induced myocardial protection against ischemia-reperfusion injury in mice.
    Das A, Salloum FN, Xi L, Rao YJ, Kukreja RC.
    Am J Physiol Heart Circ Physiol; 2009 May 05; 296(5):H1236-43. PubMed ID: 19286961
    [Abstract] [Full Text] [Related]

  • 4. Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice.
    Salloum FN, Abbate A, Das A, Houser JE, Mudrick CA, Qureshi IZ, Hoke NN, Roy SK, Brown WR, Prabhakar S, Kukreja RC.
    Am J Physiol Heart Circ Physiol; 2008 Mar 05; 294(3):H1398-406. PubMed ID: 18223185
    [Abstract] [Full Text] [Related]

  • 5. Sildenafil-induced peripheral analgesia and activation of the nitric oxide-cyclic GMP pathway.
    Jain NK, Patil CS, Singh A, Kulkarni SK.
    Brain Res; 2001 Aug 03; 909(1-2):170-8. PubMed ID: 11478933
    [Abstract] [Full Text] [Related]

  • 6. Cyclic GMP-dependent protein kinase Ialpha attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte.
    Das A, Smolenski A, Lohmann SM, Kukreja RC.
    J Biol Chem; 2006 Dec 15; 281(50):38644-52. PubMed ID: 17038326
    [Abstract] [Full Text] [Related]

  • 7. L-arginine and phosphodiesterase (PDE) inhibitors counteract fibrosis in the Peyronie's fibrotic plaque and related fibroblast cultures.
    Valente EG, Vernet D, Ferrini MG, Qian A, Rajfer J, Gonzalez-Cadavid NF.
    Nitric Oxide; 2003 Dec 15; 9(4):229-44. PubMed ID: 14996430
    [Abstract] [Full Text] [Related]

  • 8. Pretreatment of sildenafil attenuates ischemia-reperfusion renal injury in rats.
    Choi DE, Jeong JY, Lim BJ, Chung S, Chang YK, Lee SJ, Na KR, Kim SY, Shin YT, Lee KW.
    Am J Physiol Renal Physiol; 2009 Aug 15; 297(2):F362-70. PubMed ID: 19474186
    [Abstract] [Full Text] [Related]

  • 9. The effects of phosphodiesterase-5 inhibitor sildenafil against post-resuscitation myocardial and intestinal microcirculatory dysfunction by attenuating apoptosis and regulating microRNAs expression: essential role of nitric oxide syntheses signaling.
    Zhang Q, Wang G, Yuan W, Wu J, Wang M, Li C.
    J Transl Med; 2015 Jun 04; 13():177. PubMed ID: 26040988
    [Abstract] [Full Text] [Related]

  • 10. Sildenafil citrate attenuates a complex maze impairment induced by intracerebroventricular infusion of the NOS inhibitor Nomega-nitro-L-arginine methyl ester.
    Devan BD, Pistell PJ, Daffin LW, Nelson CM, Duffy KB, Bowker JL, Bharati IS, Sierra-Mercado D, Spangler EL, Ingram DK.
    Eur J Pharmacol; 2007 Jun 01; 563(1-3):134-40. PubMed ID: 17362916
    [Abstract] [Full Text] [Related]

  • 11. cGMP catabolism by phosphodiesterase 5A regulates cardiac adrenergic stimulation by NOS3-dependent mechanism.
    Takimoto E, Champion HC, Belardi D, Moslehi J, Mongillo M, Mergia E, Montrose DC, Isoda T, Aufiero K, Zaccolo M, Dostmann WR, Smith CJ, Kass DA.
    Circ Res; 2005 Jan 07; 96(1):100-9. PubMed ID: 15576651
    [Abstract] [Full Text] [Related]

  • 12. Sustained soluble guanylate cyclase stimulation offsets nitric-oxide synthase inhibition to restore acute cardiac modulation by sildenafil.
    Nagayama T, Zhang M, Hsu S, Takimoto E, Kass DA.
    J Pharmacol Exp Ther; 2008 Aug 07; 326(2):380-7. PubMed ID: 18456872
    [Abstract] [Full Text] [Related]

  • 13. Compartmentalization of cardiac beta-adrenergic inotropy modulation by phosphodiesterase type 5.
    Takimoto E, Belardi D, Tocchetti CG, Vahebi S, Cormaci G, Ketner EA, Moens AL, Champion HC, Kass DA.
    Circulation; 2007 Apr 24; 115(16):2159-67. PubMed ID: 17420342
    [Abstract] [Full Text] [Related]

  • 14. Nitric oxide signaling pathway in the anti-convulsant effect of adenosine against pentylenetetrazol-induced seizure threshold in mice.
    Akula KK, Dhir A, Kulkarni SK.
    Eur J Pharmacol; 2008 Jun 10; 587(1-3):129-34. PubMed ID: 18457833
    [Abstract] [Full Text] [Related]

  • 15. Ginsenoside Rd attenuates myocardial ischemia/reperfusion injury via Akt/GSK-3β signaling and inhibition of the mitochondria-dependent apoptotic pathway.
    Wang Y, Li X, Wang X, Lau W, Wang Y, Xing Y, Zhang X, Ma X, Gao F.
    PLoS One; 2013 Jun 10; 8(8):e70956. PubMed ID: 23976968
    [Abstract] [Full Text] [Related]

  • 16. Sildenafil is a pulmonary vasodilator in awake lambs with acute pulmonary hypertension.
    Weimann J, Ullrich R, Hromi J, Fujino Y, Clark MW, Bloch KD, Zapol WM.
    Anesthesiology; 2000 Jun 10; 92(6):1702-12. PubMed ID: 10839922
    [Abstract] [Full Text] [Related]

  • 17. Sildenafil attenuates renal injury in an experimental model of rat cisplatin-induced nephrotoxicity.
    Lee KW, Jeong JY, Lim BJ, Chang YK, Lee SJ, Na KR, Shin YT, Choi DE.
    Toxicology; 2009 Mar 29; 257(3):137-43. PubMed ID: 19152827
    [Abstract] [Full Text] [Related]

  • 18. Relaxant effect of sildenafil in the rabbit basilar artery.
    Salom JB, Burguete MC, Pérez-Asensio FJ, Castelló-Ruiz M, Torregrosa G, Alborch E.
    Vascul Pharmacol; 2006 Jan 29; 44(1):10-6. PubMed ID: 16325476
    [Abstract] [Full Text] [Related]

  • 19. Chronic inhibition of nitric-oxide synthase induces hypertension and erectile dysfunction in the rat that is not reversed by sildenafil.
    Gur S, Kadowitz PJ, Gurkan L, Chandra S, Dewitt SY, Harbin A, Sikka SC, Agrawal KC, Hellstrom WJ.
    BJU Int; 2010 Jul 29; 106(1):78-83. PubMed ID: 20002674
    [Abstract] [Full Text] [Related]

  • 20. Sildenafil and T-1032, phosphodiesterase type 5 inhibitors, showed a different vasorelaxant property in the isolated rat aorta.
    Mochida H, Inoue H, Takagi M, Noto T, Yano K, Kikkawa K.
    Eur J Pharmacol; 2002 Apr 05; 440(1):45-52. PubMed ID: 11959087
    [Abstract] [Full Text] [Related]

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