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283 related items for PubMed ID: 15681813

  • 1. Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death.
    Anantharam V, Kitazawa M, Latchoumycandane C, Kanthasamy A, Kanthasamy AG.
    Ann N Y Acad Sci; 2004 Dec; 1035():271-89. PubMed ID: 15681813
    [Abstract] [Full Text] [Related]

  • 2. Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.
    Anantharam V, Kitazawa M, Wagner J, Kaul S, Kanthasamy AG.
    J Neurosci; 2002 Mar 01; 22(5):1738-51. PubMed ID: 11880503
    [Abstract] [Full Text] [Related]

  • 3. Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.
    Latchoumycandane C, Anantharam V, Kitazawa M, Yang Y, Kanthasamy A, Kanthasamy AG.
    J Pharmacol Exp Ther; 2005 Apr 01; 313(1):46-55. PubMed ID: 15608081
    [Abstract] [Full Text] [Related]

  • 4. Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration.
    Kitazawa M, Anantharam V, Kanthasamy AG.
    Neuroscience; 2003 Apr 01; 119(4):945-64. PubMed ID: 12831855
    [Abstract] [Full Text] [Related]

  • 5. Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.
    Kaul S, Kanthasamy A, Kitazawa M, Anantharam V, Kanthasamy AG.
    Eur J Neurosci; 2003 Sep 01; 18(6):1387-401. PubMed ID: 14511319
    [Abstract] [Full Text] [Related]

  • 6. Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease.
    Afeseh Ngwa H, Kanthasamy A, Anantharam V, Song C, Witte T, Houk R, Kanthasamy AG.
    Toxicol Appl Pharmacol; 2009 Oct 15; 240(2):273-85. PubMed ID: 19646462
    [Abstract] [Full Text] [Related]

  • 7. Activation of protein kinase C delta by proteolytic cleavage contributes to manganese-induced apoptosis in dopaminergic cells: protective role of Bcl-2.
    Kitazawa M, Anantharam V, Yang Y, Hirata Y, Kanthasamy A, Kanthasamy AG.
    Biochem Pharmacol; 2005 Jan 01; 69(1):133-46. PubMed ID: 15588722
    [Abstract] [Full Text] [Related]

  • 8. A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models.
    Kanthasamy AG, Anantharam V, Zhang D, Latchoumycandane C, Jin H, Kaul S, Kanthasamy A.
    Free Radic Biol Med; 2006 Nov 15; 41(10):1578-89. PubMed ID: 17045926
    [Abstract] [Full Text] [Related]

  • 9. Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease.
    Kanthasamy AG, Kitazawa M, Yang Y, Anantharam V, Kanthasamy A.
    Mol Brain; 2008 Oct 22; 1():12. PubMed ID: 18945348
    [Abstract] [Full Text] [Related]

  • 10. Wild-type alpha-synuclein interacts with pro-apoptotic proteins PKCdelta and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death.
    Kaul S, Anantharam V, Kanthasamy A, Kanthasamy AG.
    Brain Res Mol Brain Res; 2005 Sep 13; 139(1):137-52. PubMed ID: 15978696
    [Abstract] [Full Text] [Related]

  • 11. Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease.
    Latchoumycandane C, Anantharam V, Jin H, Kanthasamy A, Kanthasamy A.
    Toxicol Appl Pharmacol; 2011 Nov 01; 256(3):314-23. PubMed ID: 21846476
    [Abstract] [Full Text] [Related]

  • 12. Oxidative stress and mitochondrial-mediated apoptosis in dopaminergic cells exposed to methylcyclopentadienyl manganese tricarbonyl.
    Kitazawa M, Wagner JR, Kirby ML, Anantharam V, Kanthasamy AG.
    J Pharmacol Exp Ther; 2002 Jul 01; 302(1):26-35. PubMed ID: 12065696
    [Abstract] [Full Text] [Related]

  • 13. Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells.
    Kaul S, Anantharam V, Yang Y, Choi CJ, Kanthasamy A, Kanthasamy AG.
    J Biol Chem; 2005 Aug 05; 280(31):28721-30. PubMed ID: 15961393
    [Abstract] [Full Text] [Related]

  • 14. α-Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinson's disease.
    Harischandra DS, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG.
    Toxicol Sci; 2015 Feb 05; 143(2):454-68. PubMed ID: 25416158
    [Abstract] [Full Text] [Related]

  • 15. Chronic low-dose oxidative stress induces caspase-3-dependent PKCdelta proteolytic activation and apoptosis in a cell culture model of dopaminergic neurodegeneration.
    Carvour M, Song C, Kaul S, Anantharam V, Kanthasamy A, Kanthasamy A.
    Ann N Y Acad Sci; 2008 Oct 05; 1139():197-205. PubMed ID: 18991865
    [Abstract] [Full Text] [Related]

  • 16. Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration.
    Yang Y, Kaul S, Zhang D, Anantharam V, Kanthasamy AG.
    Mol Cell Neurosci; 2004 Mar 05; 25(3):406-21. PubMed ID: 15033169
    [Abstract] [Full Text] [Related]

  • 17. Opposing roles of prion protein in oxidative stress- and ER stress-induced apoptotic signaling.
    Anantharam V, Kanthasamy A, Choi CJ, Martin DP, Latchoumycandane C, Richt JA, Kanthasamy AG.
    Free Radic Biol Med; 2008 Dec 01; 45(11):1530-41. PubMed ID: 18835352
    [Abstract] [Full Text] [Related]

  • 18. Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation.
    Sun F, Kanthasamy A, Song C, Yang Y, Anantharam V, Kanthasamy AG.
    J Cell Mol Med; 2008 Dec 01; 12(6A):2467-81. PubMed ID: 18298651
    [Abstract] [Full Text] [Related]

  • 19. Microarray analysis of oxidative stress regulated genes in mesencephalic dopaminergic neuronal cells: relevance to oxidative damage in Parkinson's disease.
    Anantharam V, Lehrmann E, Kanthasamy A, Yang Y, Banerjee P, Becker KG, Freed WJ, Kanthasamy AG.
    Neurochem Int; 2007 May 01; 50(6):834-47. PubMed ID: 17397968
    [Abstract] [Full Text] [Related]

  • 20. Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress signaling events.
    Singh N, Lawana V, Luo J, Phong P, Abdalla A, Palanisamy B, Rokad D, Sarkar S, Jin H, Anantharam V, Kanthasamy AG, Kanthasamy A.
    Neurobiol Dis; 2018 Sep 01; 117():82-113. PubMed ID: 29859868
    [Abstract] [Full Text] [Related]

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