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457 related items for PubMed ID: 15681821

  • 1. Modulation of prosurvival signaling in fibroblasts by a protein kinase inhibitor protects against fibrotic tissue injury.
    Vittal R, Horowitz JC, Moore BB, Zhang H, Martinez FJ, Toews GB, Standiford TJ, Thannickal VJ.
    Am J Pathol; 2005 Feb; 166(2):367-75. PubMed ID: 15681821
    [Abstract] [Full Text] [Related]

  • 2. Antifibrotic effects of focal adhesion kinase inhibitor in bleomycin-induced pulmonary fibrosis in mice.
    Kinoshita K, Aono Y, Azuma M, Kishi J, Takezaki A, Kishi M, Makino H, Okazaki H, Uehara H, Izumi K, Sone S, Nishioka Y.
    Am J Respir Cell Mol Biol; 2013 Oct; 49(4):536-43. PubMed ID: 23642017
    [Abstract] [Full Text] [Related]

  • 3. The inhibitory effect of ginsan on TGF-β mediated fibrotic process.
    Ahn JY, Kim MH, Lim MJ, Park S, Lee SL, Yun YS, Song JY.
    J Cell Physiol; 2011 May; 226(5):1241-7. PubMed ID: 20945375
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  • 4. Tubastatin ameliorates pulmonary fibrosis by targeting the TGFβ-PI3K-Akt pathway.
    Saito S, Zhuang Y, Shan B, Danchuk S, Luo F, Korfei M, Guenther A, Lasky JA.
    PLoS One; 2017 May; 12(10):e0186615. PubMed ID: 29045477
    [Abstract] [Full Text] [Related]

  • 5. Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis.
    Wollin L, Maillet I, Quesniaux V, Holweg A, Ryffel B.
    J Pharmacol Exp Ther; 2014 May; 349(2):209-20. PubMed ID: 24556663
    [Abstract] [Full Text] [Related]

  • 6. Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts.
    Horowitz JC, Rogers DS, Sharma V, Vittal R, White ES, Cui Z, Thannickal VJ.
    Cell Signal; 2007 Apr; 19(4):761-71. PubMed ID: 17113264
    [Abstract] [Full Text] [Related]

  • 7. Focal Adhesion Kinase Regulates Fibroblast Migration via Integrin beta-1 and Plays a Central Role in Fibrosis.
    Zhao XK, Cheng Y, Liang Cheng M, Yu L, Mu M, Li H, Liu Y, Zhang B, Yao Y, Guo H, Wang R, Zhang Q.
    Sci Rep; 2016 Jan 14; 6():19276. PubMed ID: 26763945
    [Abstract] [Full Text] [Related]

  • 8. Effects of the protein kinase inhibitor, imatinib mesylate, on epithelial/mesenchymal phenotypes: implications for treatment of fibrotic diseases.
    Vittal R, Zhang H, Han MK, Moore BB, Horowitz JC, Thannickal VJ.
    J Pharmacol Exp Ther; 2007 Apr 14; 321(1):35-44. PubMed ID: 17218487
    [Abstract] [Full Text] [Related]

  • 9. Therapeutic targeting of SRC kinase in myofibroblast differentiation and pulmonary fibrosis.
    Hu M, Che P, Han X, Cai GQ, Liu G, Antony V, Luckhardt T, Siegal GP, Zhou Y, Liu RM, Desai LP, O'Reilly PJ, Thannickal VJ, Ding Q.
    J Pharmacol Exp Ther; 2014 Oct 14; 351(1):87-95. PubMed ID: 25047515
    [Abstract] [Full Text] [Related]

  • 10. Neurotrophic tyrosine kinase receptor B/neurotrophin 4 signaling axis is perturbed in clinical and experimental pulmonary fibrosis.
    Avcuoglu S, Wygrecka M, Marsh LM, Günther A, Seeger W, Weissmann N, Fink L, Morty RE, Kwapiszewska G.
    Am J Respir Cell Mol Biol; 2011 Oct 14; 45(4):768-80. PubMed ID: 21330466
    [Abstract] [Full Text] [Related]

  • 11. Transforming growth factor-beta1 stimulated protein kinase B serine-473 and focal adhesion kinase tyrosine phosphorylation dependent on cell adhesion in human hepatocellular carcinoma SMMC-7721 cells.
    Xu Z, Ma DZ, Wang LY, Su JM, Zha XL.
    Biochem Biophys Res Commun; 2003 Dec 12; 312(2):388-96. PubMed ID: 14637150
    [Abstract] [Full Text] [Related]

  • 12. Dasatinib attenuated bleomycin-induced pulmonary fibrosis in mice.
    Yilmaz O, Oztay F, Kayalar O.
    Growth Factors; 2015 Dec 12; 33(5-6):366-75. PubMed ID: 26607773
    [Abstract] [Full Text] [Related]

  • 13. HGF reduces advancing lung fibrosis in mice: a potential role for MMP-dependent myofibroblast apoptosis.
    Mizuno S, Matsumoto K, Li MY, Nakamura T.
    FASEB J; 2005 Apr 12; 19(6):580-2. PubMed ID: 15665032
    [Abstract] [Full Text] [Related]

  • 14. Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase.
    Thannickal VJ, Lee DY, White ES, Cui Z, Larios JM, Chacon R, Horowitz JC, Day RM, Thomas PE.
    J Biol Chem; 2003 Apr 04; 278(14):12384-9. PubMed ID: 12531888
    [Abstract] [Full Text] [Related]

  • 15. Src inhibition blocks renal interstitial fibroblast activation and ameliorates renal fibrosis.
    Yan Y, Ma L, Zhou X, Ponnusamy M, Tang J, Zhuang MA, Tolbert E, Bayliss G, Bai J, Zhuang S.
    Kidney Int; 2016 Jan 04; 89(1):68-81. PubMed ID: 26444028
    [Abstract] [Full Text] [Related]

  • 16. Spleen tyrosine kinase (Syk) inhibitor fostamatinib limits tissue damage and fibrosis in a bleomycin-induced scleroderma mouse model.
    Pamuk ON, Can G, Ayvaz S, Karaca T, Pamuk GE, Demirtas S, Tsokos GC.
    Clin Exp Rheumatol; 2015 Jan 04; 33(4 Suppl 91):S15-22. PubMed ID: 26148346
    [Abstract] [Full Text] [Related]

  • 17. Peptide-mediated inhibition of mitogen-activated protein kinase-activated protein kinase-2 ameliorates bleomycin-induced pulmonary fibrosis.
    Vittal R, Fisher A, Gu H, Mickler EA, Panitch A, Lander C, Cummings OW, Sandusky GE, Wilkes DS.
    Am J Respir Cell Mol Biol; 2013 Jul 04; 49(1):47-57. PubMed ID: 23470623
    [Abstract] [Full Text] [Related]

  • 18. Imatinib mesylate inhibits the profibrogenic activity of TGF-beta and prevents bleomycin-mediated lung fibrosis.
    Daniels CE, Wilkes MC, Edens M, Kottom TJ, Murphy SJ, Limper AH, Leof EB.
    J Clin Invest; 2004 Nov 04; 114(9):1308-16. PubMed ID: 15520863
    [Abstract] [Full Text] [Related]

  • 19. Overcoming interferon (IFN)-γ resistance ameliorates transforming growth factor (TGF)-β-mediated lung fibroblast-to-myofibroblast transition and bleomycin-induced pulmonary fibrosis.
    Chang CJ, Lin CF, Lee CH, Chuang HC, Shih FC, Wan SW, Tai C, Chen CL.
    Biochem Pharmacol; 2021 Jan 04; 183():114356. PubMed ID: 33285108
    [Abstract] [Full Text] [Related]

  • 20. Constitutive phosphorylation of focal adhesion kinase is involved in the myofibroblast differentiation of scleroderma fibroblasts.
    Mimura Y, Ihn H, Jinnin M, Asano Y, Yamane K, Tamaki K.
    J Invest Dermatol; 2005 May 04; 124(5):886-92. PubMed ID: 15854026
    [Abstract] [Full Text] [Related]

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