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119 related items for PubMed ID: 15686498

  • 1. Mutational studies using a cation-conducting GABAA receptor reveal the selectivity determinants of the Cys-loop family of ligand-gated ion channels.
    Jensen ML, Pedersen LN, Timmermann DB, Schousboe A, Ahring PK.
    J Neurochem; 2005 Feb; 92(4):962-72. PubMed ID: 15686498
    [Abstract] [Full Text] [Related]

  • 2. Charge selectivity of the Cys-loop family of ligand-gated ion channels.
    Jensen ML, Schousboe A, Ahring PK.
    J Neurochem; 2005 Jan; 92(2):217-25. PubMed ID: 15663470
    [Abstract] [Full Text] [Related]

  • 3. Ligand-gated ion channels: mechanisms underlying ion selectivity.
    Keramidas A, Moorhouse AJ, Schofield PR, Barry PH.
    Prog Biophys Mol Biol; 2004 Oct; 86(2):161-204. PubMed ID: 15288758
    [Abstract] [Full Text] [Related]

  • 4. The Cys-loop superfamily of ligand-gated ion channels: the impact of receptor structure on function.
    Connolly CN, Wafford KA.
    Biochem Soc Trans; 2004 Jun; 32(Pt3):529-34. PubMed ID: 15157178
    [Abstract] [Full Text] [Related]

  • 5. Mutations in the channel domain of a neuronal nicotinic receptor convert ion selectivity from cationic to anionic.
    Galzi JL, Devillers-Thiéry A, Hussy N, Bertrand S, Changeux JP, Bertrand D.
    Nature; 1992 Oct 08; 359(6395):500-5. PubMed ID: 1383829
    [Abstract] [Full Text] [Related]

  • 6. Contribution of the beta subunit M2 segment to the ion-conducting pathway of the acetylcholine receptor.
    Zhang H, Karlin A.
    Biochemistry; 1998 Jun 02; 37(22):7952-64. PubMed ID: 9609688
    [Abstract] [Full Text] [Related]

  • 7. Evaluation of a proposed mechanism of ligand-gated ion channel activation in the GABAA and glycine receptors.
    Kash TL, Kim T, Trudell JR, Harrison NL.
    Neurosci Lett; 2004 Nov 23; 371(2-3):230-4. PubMed ID: 15519763
    [Abstract] [Full Text] [Related]

  • 8. Molecular determinants of single-channel conductance and ion selectivity in the Cys-loop family: insights from the 5-HT3 receptor.
    Peters JA, Hales TG, Lambert JJ.
    Trends Pharmacol Sci; 2005 Nov 23; 26(11):587-94. PubMed ID: 16194573
    [Abstract] [Full Text] [Related]

  • 9. EXP-1 is an excitatory GABA-gated cation channel.
    Beg AA, Jorgensen EM.
    Nat Neurosci; 2003 Nov 23; 6(11):1145-52. PubMed ID: 14555952
    [Abstract] [Full Text] [Related]

  • 10. Coupling of agonist binding to channel gating in the GABA(A) receptor.
    Kash TL, Jenkins A, Kelley JC, Trudell JR, Harrison NL.
    Nature; 2003 Jan 16; 421(6920):272-5. PubMed ID: 12529644
    [Abstract] [Full Text] [Related]

  • 11. A single P-loop glutamate point mutation to either lysine or arginine switches the cation-anion selectivity of the CNGA2 channel.
    Qu W, Moorhouse AJ, Chandra M, Pierce KD, Lewis TM, Barry PH.
    J Gen Physiol; 2006 Apr 16; 127(4):375-89. PubMed ID: 16533895
    [Abstract] [Full Text] [Related]

  • 12. Identification of two critical residues within the Cys-loop sequence that determine fast-gating kinetics in a pentameric ligand-gated ion channel.
    Grutter T, de Carvalho LP, Dufresne V, Taly A, Changeux JP.
    J Mol Neurosci; 2006 Apr 16; 30(1-2):63-4. PubMed ID: 17192629
    [Abstract] [Full Text] [Related]

  • 13. The transmembrane domain of the 5-HT3 receptor: its role in selectivity and gating.
    Lummis SC.
    Biochem Soc Trans; 2004 Jun 16; 32(Pt3):535-9. PubMed ID: 15157179
    [Abstract] [Full Text] [Related]

  • 14. A cytoplasmic region determines single-channel conductance in 5-HT3 receptors.
    Kelley SP, Dunlop JI, Kirkness EF, Lambert JJ, Peters JA.
    Nature; 2003 Jul 17; 424(6946):321-4. PubMed ID: 12867984
    [Abstract] [Full Text] [Related]

  • 15. Ion channels of N-terminally linked alamethicin dimers: enhancement of cation-selectivity by substitution of Glu for Gln at position 7.
    Okazaki T, Nagaoka Y, Asami K.
    Bioelectrochemistry; 2007 May 17; 70(2):380-6. PubMed ID: 16814617
    [Abstract] [Full Text] [Related]

  • 16. Identification of channel-lining residues in the M2 membrane-spanning segment of the GABA(A) receptor alpha1 subunit.
    Xu M, Akabas MH.
    J Gen Physiol; 1996 Feb 17; 107(2):195-205. PubMed ID: 8833341
    [Abstract] [Full Text] [Related]

  • 17. Tryptophan-scanning mutagenesis in the S1 domain of mammalian HCN channel reveals residues critical for voltage-gated activation.
    Ishii TM, Nakashima N, Ohmori H.
    J Physiol; 2007 Mar 01; 579(Pt 2):291-301. PubMed ID: 17185333
    [Abstract] [Full Text] [Related]

  • 18. Effects of a mutation in the TM2-TM3 linker region of the glycine receptor alpha1 subunit on gating and allosteric modulation.
    Dupre ML, Broyles JM, Mihic SJ.
    Brain Res; 2007 Jun 04; 1152():1-9. PubMed ID: 17434460
    [Abstract] [Full Text] [Related]

  • 19. Barriers to ion translocation in cationic and anionic receptors from the Cys-loop family.
    Ivanov I, Cheng X, Sine SM, McCammon JA.
    J Am Chem Soc; 2007 Jul 04; 129(26):8217-24. PubMed ID: 17552523
    [Abstract] [Full Text] [Related]

  • 20. A prokaryotic perspective on pentameric ligand-gated ion channel structure.
    Hilf RJ, Dutzler R.
    Curr Opin Struct Biol; 2009 Aug 04; 19(4):418-24. PubMed ID: 19646860
    [Abstract] [Full Text] [Related]

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